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Volumn 111, Issue 6, 1998, Pages 759-767

Psoralen photoactivation promotes morphological and functional changes in fibroblasts in vitro reminiscent of cellular senescence

Author keywords

Aging; Fibroblast; Matrix metalloprotease; Psoralen; Reactive oxygen species; Ultraviolet A

Indexed keywords

BETA GALACTOSIDASE; COLLAGENASE; HYDROGEN PEROXIDE; METHOXSALEN; STROMELYSIN; SUPEROXIDE; TISSUE INHIBITOR OF METALLOPROTEINASE;

EID: 18544395710     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (59)

References (75)
  • 1
    • 0022352231 scopus 로고
    • 12-0-Tetradecanoylphorbol-13-acetate (TPA)-induced gene sequences in human primary diploid fibroblasts and their expression in SV40-transformed fibroblasts
    • Angel, P., Rahmsdorf, H. J., Pöting, A., Lücke-Huhle, C. and Herrlich, P. (1985). 12-0-Tetradecanoylphorbol-13-acetate (TPA)-induced gene sequences in human primary diploid fibroblasts and their expression in SV40-transformed fibroblasts. J. Cell. Biochem. 29, 351-360.
    • (1985) J. Cell. Biochem. , vol.29 , pp. 351-360
    • Angel, P.1    Rahmsdorf, H.J.2    Pöting, A.3    Lücke-Huhle, C.4    Herrlich, P.5
  • 2
    • 0023625090 scopus 로고
    • Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated transacting factor
    • Angel, P., Imagawa, M., Chiu, R., Stein, B., Imbra, R. J., Rahmsdorf, H. J., Jonat, C., Herrlich, P. and Karin, M. (1987). Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated transacting factor. Cell 49, 729-739.
    • (1987) Cell , vol.49 , pp. 729-739
    • Angel, P.1    Imagawa, M.2    Chiu, R.3    Stein, B.4    Imbra, R.J.5    Rahmsdorf, H.J.6    Jonat, C.7    Herrlich, P.8    Karin, M.9
  • 4
    • 0026699714 scopus 로고
    • Fibroblasts in normal and pathological terminal differentiation, aging, apoptosis and transformation
    • Bayreuther, K., Francz, P. I. and Rodemann, H. P. (1992). Fibroblasts in normal and pathological terminal differentiation, aging, apoptosis and transformation. Arch. Geront. Geriatr: Suppl. 3, 47-74.
    • (1992) Arch. Geront. Geriatr: Suppl. 3 , pp. 47-74
    • Bayreuther, K.1    Francz, P.I.2    Rodemann, H.P.3
  • 7
    • 0030025660 scopus 로고    scopus 로고
    • Replicative senescence: An old lives tale?
    • Campisi, J. (1996). Replicative senescence: An old lives tale? Cell 84, 497-500.
    • (1996) Cell , vol.84 , pp. 497-500
    • Campisi, J.1
  • 8
    • 0000962421 scopus 로고    scopus 로고
    • Control of replicative senescence
    • ed. E. L. Schneider and J. W. Rowe, Academic Press. San Diego
    • Campisi, J., Dimri, G. and Hara, E. (1996). Control of replicative senescence. In Handbook of the Biology of Aging. 4th edn (ed. E. L. Schneider and J. W. Rowe), pp. 121-149, Academic Press. San Diego.
    • (1996) Handbook of the Biology of Aging. 4th Edn , pp. 121-149
    • Campisi, J.1    Dimri, G.2    Hara, E.3
  • 10
    • 0028797399 scopus 로고
    • The cellular responses to DNA damage
    • Carr, A. M. and Hoekstra, M. F. (1995). The cellular responses to DNA damage. Trends Cell Bid. 5, 32-40
    • (1995) Trends Cell Bid. , vol.5 , pp. 32-40
    • Carr, A.M.1    Hoekstra, M.F.2
  • 12
    • 0027792335 scopus 로고
    • Transgenic mice overexpressing copper-zinic superoxide dismutuse: A model for the studs of radical machanisms and aging
    • Ceballos-Picot, J. (1993). Transgenic mice overexpressing copper-zinic superoxide dismutuse: A model for the studs of radical machanisms and aging. CR Sciences Soc. Biol. Fil. 187, 308-323.
    • (1993) CR Sciences Soc. Biol. Fil. , vol.187 , pp. 308-323
    • Ceballos-Picot, J.1
  • 14
    • 0027163464 scopus 로고
    • Replicative senescence of human fibroblast-like cells in culture
    • Cristofalo, V. J. and Pignolo. R. J. (1993). Replicative senescence of human fibroblast-like cells in culture. Physiol. Rev. 73, 617-638.
    • (1993) Physiol. Rev. , vol.73 , pp. 617-638
    • Cristofalo, V.J.1    Pignolo, R.J.2
  • 15
    • 0029921312 scopus 로고    scopus 로고
    • Molecular markers of senescence in fibroblast-like cultures
    • Cristofalo, V. J. and Pignolo, R. J. (1996). Molecular markers of senescence in fibroblast-like cultures. Exp. Gerontol. 31, 111-123.
    • (1996) Exp. Gerontol. , vol.31 , pp. 111-123
    • Cristofalo, V.J.1    Pignolo, R.J.2
  • 16
    • 0026514680 scopus 로고
    • Cu/Zn superoxide dismutase mRNA and enzyme activity, and susceptibility to lipid peroxidation, increases with aging in murine brains
    • de Haan, J. B., Newman, J. D. and Kola, I. (1992). Cu/Zn superoxide dismutase mRNA and enzyme activity, and susceptibility to lipid peroxidation, increases with aging in murine brains. Mol. Brain Res. 13. 179-186.
    • (1992) Mol. Brain Res. , vol.13 , pp. 179-186
    • De Haan, J.B.1    Newman, J.D.2    Kola, I.3
  • 17
    • 0030068056 scopus 로고    scopus 로고
    • Elevation in the ratio of Cu/Zn - Superoxide dismutase to glutathione peroxidase activity induces features of cellular senescence and this effect is mediated by hydrogen peroxide
    • de Haan, J. B., Christiane, F., Iannello, R. C., Bladier, C., Kelner, M. J. and Kola, I. (1996). Elevation in the ratio of Cu/Zn - superoxide dismutase to glutathione peroxidase activity induces features of cellular senescence and this effect is mediated by hydrogen peroxide. Hum. Mol Genet. 5, 283-292
    • (1996) Hum. Mol Genet. , vol.5 , pp. 283-292
    • De Haan, J.B.1    Christiane, F.2    Iannello, R.C.3    Bladier, C.4    Kelner, M.J.5    Kola, I.6
  • 19
    • 0019841405 scopus 로고
    • Variability in collagen and fibroncctin synthesis by scleroderma fibroblasts in primary culture
    • Fleischmajer. R., Perlish, J. S., Krieg, T. and Timpl, R. (1981). Variability in collagen and fibroncctin synthesis by scleroderma fibroblasts in primary culture. J. Invest. Dermatol. 76, 400-403.
    • (1981) J. Invest. Dermatol. , vol.76 , pp. 400-403
    • Fleischmajer, R.1    Perlish, J.S.2    Krieg, T.3    Timpl, R.4
  • 20
    • 0025145238 scopus 로고
    • The human fibroblast comes of age
    • Goldstein, S. (1990). The human fibroblast comes of age. Science 249, 1129-1133.
    • (1990) Science , vol.249 , pp. 1129-1133
    • Goldstein, S.1
  • 21
    • 0021287698 scopus 로고
    • Rapid colorimetric assay for cell viability: Application to the quantitation of cytotoxic and growth inhibitory kines
    • Green, L. M., Reade, J. L. and Ware, C. F. (1984). Rapid colorimetric assay for cell viability: application to the quantitation of cytotoxic and growth inhibitory kines. J. Immnnol. Meth. 70, 257-268.
    • (1984) J. Immnnol. Meth. , vol.70 , pp. 257-268
    • Green, L.M.1    Reade, J.L.2    Ware, C.F.3
  • 22
    • 0020444895 scopus 로고
    • Mechanism of action, metabolism and toxicity of buthionine sulfoximine and its higher analogs, potent inhibitors of glutathione synthesis
    • Griffith, O. W. (1982). Mechanism of action, metabolism and toxicity of buthionine sulfoximine and its higher analogs, potent inhibitors of glutathione synthesis. J. Biol. Chem. 257, 2704-3712.
    • (1982) J. Biol. Chem. , vol.257 , pp. 2704-3712
    • Griffith, O.W.1
  • 23
    • 77049308856 scopus 로고
    • Aging: A theory based on free radical and radiation chemistry
    • Harman, D. (1956). Aging: a theory based on free radical and radiation chemistry. J. Gerontol. 11, 298-300.
    • (1956) J. Gerontol. , vol.11 , pp. 298-300
    • Harman, D.1
  • 24
    • 0026775958 scopus 로고
    • Free radical theory of aging
    • Harman, D. (1992). Free radical theory of aging. Mutat. Res. 275, 257-266.
    • (1992) Mutat. Res. , vol.275 , pp. 257-266
    • Harman, D.1
  • 25
    • 50549218525 scopus 로고
    • The limited in vitro lifetime of human diploid cell strains
    • Hayflick, L. (1964). The limited in vitro lifetime of human diploid cell strains. Exp. Cell. Res. 37, 614-636.
    • (1964) Exp. Cell. Res. , vol.37 , pp. 614-636
    • Hayflick, L.1
  • 26
    • 0017294656 scopus 로고
    • In vivo inhibition of superoxide dismutase in mice by diethyldithiocarbamate
    • Heikkila, R. E., Cabbat, F. S. and Cohen, G. (1976). In vivo inhibition of superoxide dismutase in mice by diethyldithiocarbamate. J. Biol. Chem. 251, 2182-2185.
    • (1976) J. Biol. Chem. , vol.251 , pp. 2182-2185
    • Heikkila, R.E.1    Cabbat, F.S.2    Cohen, G.3
  • 27
    • 0027283837 scopus 로고
    • UVA irradiation stimulates the synthesis of various matrix-metalloproteinases (MMPs) in cultured human fibroblasts
    • Herrmann, G., Wlaschek, M., Lange, T. S., Prenzel, K., Goerz, G. and Scharffetter-Kochanek, K. (1993). UVA irradiation stimulates the synthesis of various matrix-metalloproteinases (MMPs) in cultured human fibroblasts. Exp. Dermatol. 2, 92-97.
    • (1993) Exp. Dermatol. , vol.2 , pp. 92-97
    • Herrmann, G.1    Wlaschek, M.2    Lange, T.S.3    Prenzel, K.4    Goerz, G.5    Scharffetter-Kochanek, K.6
  • 28
    • 0029815199 scopus 로고    scopus 로고
    • Pathogenic implication of matrix-metalloproteinases (MMPs) and their counteracting inhibitor TIMP-1 in the photodamage of human porphyria cutanea tarda (PCT)
    • Herrmann, G., Wlaschek, M., Bolsen, K., Prenzel, K., Goerz, G. and Scharffetter-Kochanek, K. (1996). Pathogenic implication of matrix-metalloproteinases (MMPs) and their counteracting inhibitor TIMP-1 in the photodamage of human porphyria cutanea tarda (PCT). J. Invest. Dennatol. 107, 398-403.
    • (1996) J. Invest. Dennatol. , vol.107 , pp. 398-403
    • Herrmann, G.1    Wlaschek, M.2    Bolsen, K.3    Prenzel, K.4    Goerz, G.5    Scharffetter-Kochanek, K.6
  • 29
    • 0020425195 scopus 로고
    • Decreased in-vitro litespan of fibroblasts derived from skin exposed to photochemotherapy in vivo
    • Jacobson-Kram, D., Roe, J. L., Williams, J. R., Gange, R. W. and Parrish, J. A. (1982). Decreased in-vitro litespan of fibroblasts derived from skin exposed to photochemotherapy in vivo. Lancet 18, 1399-1400.
    • (1982) Lancet , vol.18 , pp. 1399-1400
    • Jacobson-Kram, D.1    Roe, J.L.2    Williams, J.R.3    Gange, R.W.4    Parrish, J.A.5
  • 30
    • 0020538948 scopus 로고
    • Production of singlet oxygen and superoxide radicals by psoralens and their biological significance
    • Joshi, P. C. and Pathak, M. A. (1983). Production of singlet oxygen and superoxide radicals by psoralens and their biological significance. Biochem. Biophys. Res. Commun. 29, 638-646.
    • (1983) Biochem. Biophys. Res. Commun. , vol.29 , pp. 638-646
    • Joshi, P.C.1    Pathak, M.A.2
  • 31
    • 7444249085 scopus 로고
    • The biochemistry of desferrioxamine and its relation to iron metabolism
    • Keberle, H. (1964). The biochemistry of desferrioxamine and its relation to iron metabolism. Ann. NY Acad. Sci. 119, 758-768.
    • (1964) Ann. NY Acad. Sci. , vol.119 , pp. 758-768
    • Keberle, H.1
  • 33
    • 0014695180 scopus 로고
    • Early destructive effect of sunlight on human skin
    • Kligman, A. M. (1969). Early destructive effect of sunlight on human skin. J. Am. Med. Assoc. 210, 2377-2380.
    • (1969) J. Am. Med. Assoc. , vol.210 , pp. 2377-2380
    • Kligman, A.M.1
  • 34
  • 35
    • 0026556492 scopus 로고
    • Endogenous glutathione levels modulate both constitutive and UVA radiation/hydrogen peroxide inducible expression of the human heme oxygenase gene
    • Lautier, D., Luscher, P. and Tyrell, R. M. (1992). Endogenous glutathione levels modulate both constitutive and UVA radiation/hydrogen peroxide inducible expression of the human heme oxygenase gene. Carcinogenesis 13, 227-232.
    • (1992) Carcinogenesis , vol.13 , pp. 227-232
    • Lautier, D.1    Luscher, P.2    Tyrell, R.M.3
  • 36
    • 0026541143 scopus 로고
    • Activation of extracallular signal-regulated kinase, ERK2, by p21ras oncoprotein
    • Leevers, S. J. and Marshall, C. J. (1992). Activation of extracallular signal-regulated kinase, ERK2, by p21ras oncoprotein. EMBO J. 11, 569-574.
    • (1992) EMBO J. , vol.11 , pp. 569-574
    • Leevers, S.J.1    Marshall, C.J.2
  • 37
    • 0000474831 scopus 로고
    • Irreversible reaction of 3-amino-1, 2, 4-triazole and related inhibitors with the protein of catalase
    • Margoliash, E., Novogrodsky, A. and Schejter, A. (1960). Irreversible reaction of 3-amino-1, 2, 4-triazole and related inhibitors with the protein of catalase. Biochem. J. 74, 339-348.
    • (1960) Biochem. J. , vol.74 , pp. 339-348
    • Margoliash, E.1    Novogrodsky, A.2    Schejter, A.3
  • 38
    • 0001454317 scopus 로고
    • Age related alterations in antioxidant defense
    • ed. B. P. Yu, CRC Press, Boca Raton, Ann Arbor, London, Tokyo
    • Matsuo, M. (1993). Age related alterations in antioxidant defense. In Free Radicals in Aging (ed. B. P. Yu), pp. 143-181. CRC Press, Boca Raton, Ann Arbor, London, Tokyo.
    • (1993) Free Radicals in Aging , pp. 143-181
    • Matsuo, M.1
  • 39
    • 85047689721 scopus 로고
    • Use of the inhibition of enzymatic antioxidant systems to evaluate their physiological importance
    • Michiels, C. and Remacle, J. (1988). Use of the inhibition of enzymatic antioxidant systems to evaluate their physiological importance. Eur. J. Biochem. 177, 435-441.
    • (1988) Eur. J. Biochem. , vol.177 , pp. 435-441
    • Michiels, C.1    Remacle, J.2
  • 40
    • 0002778395 scopus 로고
    • Chemical mechanisms of the bioeffects of furocumarines
    • ed. F. P. Gasparro, CRC press, Boca Raton, FL, USA
    • Midden, W. R. (1988). Chemical mechanisms of the bioeffects of furocumarines. In Psoralen DNA photobiology, vol. II (ed. F. P. Gasparro), pp. 1-51. CRC press, Boca Raton, FL, USA.
    • (1988) Psoralen DNA Photobiology , vol.2 , pp. 1-51
    • Midden, W.R.1
  • 41
    • 0026793281 scopus 로고
    • Differential expression of metalloproteinase and tissue inhibitor of metalloproteinase genes in aged human fibroblasts
    • Millis, A. J. T., Hoyle, M., McCue, H. M. and Martini, H. (1992). Differential expression of metalloproteinase and tissue inhibitor of metalloproteinase genes in aged human fibroblasts. Exp. Cell Res. 201, 373-379.
    • (1992) Exp. Cell Res. , vol.201 , pp. 373-379
    • Millis, A.J.T.1    Hoyle, M.2    McCue, H.M.3    Martini, H.4
  • 42
    • 1642268993 scopus 로고    scopus 로고
    • The effects of aging on the processing of UV-damaged DNA in human cells: Reduced DNA repair capacity and increased DNA mutability
    • Moriwaki, S. I., Ray, S., Tarone, R. E., Kraemer K. H. and Grossman, L. (1996). The effects of aging on the processing of UV-damaged DNA in human cells: reduced DNA repair capacity and increased DNA mutability. Mutat. Res. 364, 117-123.
    • (1996) Mutat. Res. , vol.364 , pp. 117-123
    • Moriwaki, S.I.1    Ray, S.2    Tarone, R.E.3    Kraemer, K.H.4    Grossman, L.5
  • 43
    • 0019370333 scopus 로고
    • A new apparatus with high radiation energy between 320-460 nm: Physical description and dermatological applications
    • Mutzhas, M. F., Hölzle, E., Hofmann, C. and Plewig, G. (1981). A new apparatus with high radiation energy between 320-460 nm: physical description and dermatological applications. J. Invest. Dermatol. 76, 42-47.
    • (1981) J. Invest. Dermatol. , vol.76 , pp. 42-47
    • Mutzhas, M.F.1    Hölzle, E.2    Hofmann, C.3    Plewig, G.4
  • 44
    • 0028342664 scopus 로고
    • Cloning of senescent cells derived inhibitors of DNA synthesis using an expression screen
    • Noda, A., Ning, Y., Venable, S. F., Pereira-Smith, O. M and Smith, J. R. (1994). Cloning of senescent cells derived inhibitors of DNA synthesis using an expression screen. Exp Cell Res. 211, 90-98.
    • (1994) Exp Cell Res. , vol.211 , pp. 90-98
    • Noda, A.1    Ning, Y.2    Venable, S.F.3    Pereira-Smith, O.M.4    Smith, J.R.5
  • 45
    • 0021932266 scopus 로고
    • Connective tissue alterations in skin exposed to natural and therapeutic UV-radiation
    • Oikarinen, A., Karvonen, J., Uitto, J. and Hannuksela, M. (1985). Connective tissue alterations in skin exposed to natural and therapeutic UV-radiation. Photodermatology 2, 15-26.
    • (1985) Photodermatology , vol.2 , pp. 15-26
    • Oikarinen, A.1    Karvonen, J.2    Uitto, J.3    Hannuksela, M.4
  • 47
    • 0027620470 scopus 로고
    • Improved HPLC analysis of 8-methoxypsoralen monoadducts and crosslinks in polynucleotide, DNA and cellular systems: Analysis of split dose protocols
    • Olack, G. A., Gattolin, P. and Gasparro, F. P. (1993). Improved HPLC analysis of 8-methoxypsoralen monoadducts and crosslinks in polynucleotide, DNA and cellular systems: analysis of split dose protocols. Photochem. Photobiol. 57, 941-949.
    • (1993) Photochem. Photobiol. , vol.57 , pp. 941-949
    • Olack, G.A.1    Gattolin, P.2    Gasparro, F.P.3
  • 48
    • 0028220114 scopus 로고
    • Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster
    • Orr, W. C. and Sohal, R. S. (1994). Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster. Science 263, 1128-1130.
    • (1994) Science , vol.263 , pp. 1128-1130
    • Orr, W.C.1    Sohal, R.S.2
  • 49
    • 0019980501 scopus 로고
    • Molecular aspects of drug photosensitivity with special emphasis on psoralen photosensitization reaction
    • Pathak, M. A. (1982). Molecular aspects of drug photosensitivity with special emphasis on psoralen photosensitization reaction. J. Nat. Cancer lust. 69, 163-170.
    • (1982) J. Nat. Cancer Lust. , vol.69 , pp. 163-170
    • Pathak, M.A.1
  • 50
    • 0020560843 scopus 로고
    • The nature and molecular basis of cutaneous photosensitivity reactions to psoralens and coal tar
    • Pathak, M. A. and Joshi, P. C. (1983). The nature and molecular basis of cutaneous photosensitivity reactions to psoralens and coal tar. J. Invest. Dermaiol 80, 66(s)-74(s).
    • (1983) J. Invest. Dermaiol , vol.80
    • Pathak, M.A.1    Joshi, P.C.2
  • 51
    • 0026661226 scopus 로고
    • Ultraviolet A irradiation stimulates collagenase production in cultured human fibroblasts
    • Petersen, M. J., Hansen, C. and Craig, S. (1992). Ultraviolet A irradiation stimulates collagenase production in cultured human fibroblasts. J. Invest. Dermatol. 99, 440-444.
    • (1992) J. Invest. Dermatol. , vol.99 , pp. 440-444
    • Petersen, M.J.1    Hansen, C.2    Craig, S.3
  • 52
    • 0004717610 scopus 로고
    • Genomic and mitochondrial DNA alterations with aging
    • ed. E. L. Schneider and J. W. Rowe, Academic Press, Inc., San Diego, London
    • Randerath, K., Randerath, E., Filburn, C. (1995). Genomic and mitochondrial DNA alterations with aging. In Handbook of the Biology of Aging (ed. E. L. Schneider and J. W. Rowe), pp. 198-213. Academic Press, Inc., San Diego, London.
    • (1995) Handbook of the Biology of Aging , pp. 198-213
    • Randerath, K.1    Randerath, E.2    Filburn, C.3
  • 53
    • 0024343128 scopus 로고
    • DNA damage and repair during cellular aging
    • Rattan, S. J. (1989). DNA damage and repair during cellular aging. Int. Rev. Cytol. 116, 47-88.
    • (1989) Int. Rev. Cytol. , vol.116 , pp. 47-88
    • Rattan, S.J.1
  • 54
    • 0028894557 scopus 로고
    • Low levels of reactive oxygen species as modulators of cell function
    • Remacle, J., Raes, M., Toussaint, O., Renard, P. and Rao, G. (1995). Low levels of reactive oxygen species as modulators of cell function. Mutat. Res. 316, 103-122.
    • (1995) Mutat. Res. , vol.316 , pp. 103-122
    • Remacle, J.1    Raes, M.2    Toussaint, O.3    Renard, P.4    Rao, G.5
  • 55
    • 0029116061 scopus 로고
    • Oxidative damage to mitochondrial DNA and its relationship to aging
    • Richter, C. (1995). Oxidative damage to mitochondrial DNA and its relationship to aging. Int. J. Biochem. Cell Biol. 27, 647-653.
    • (1995) Int. J. Biochem. Cell Biol. , vol.27 , pp. 647-653
    • Richter, C.1
  • 61
    • 0030636565 scopus 로고    scopus 로고
    • Antioxidants in disease - Mechanisms and therapeutic strategies
    • Scharffetter-Kochanek, K. (1997). Antioxidants in disease - mechanisms and therapeutic strategies. Advan. Pharmacol. , 639-655.
    • (1997) Advan. Pharmacol. , pp. 639-655
    • Scharffetter-Kochanek, K.1
  • 64
    • 0020332294 scopus 로고
    • DNA repair, aging, and cancer
    • Setlow, R. B. (1982). DNA repair, aging, and cancer. Nat. Cancer Inst. Monogr. 60, 249-255.
    • (1982) Nat. Cancer Inst. Monogr. , vol.60 , pp. 249-255
    • Setlow, R.B.1
  • 65
    • 0024457611 scopus 로고
    • Cloning the genes for human stromelysin and stromelysin 2: Differential expression in rheumatoid synovial fibroblasts
    • Sirum, K. L. and Brinckerhoff, C. E. (1989). Cloning the genes for human stromelysin and stromelysin 2: differential expression in rheumatoid synovial fibroblasts. Biochemistry 28, 8691-8698.
    • (1989) Biochemistry , vol.28 , pp. 8691-8698
    • Sirum, K.L.1    Brinckerhoff, C.E.2
  • 66
    • 0030038104 scopus 로고    scopus 로고
    • Replicative senescence: Implications for in vivo aging and tumor suppression
    • Smith, J. R. and Pereira-Smith, O. M. (1996). Replicative senescence: implications for in vivo aging and tumor suppression. Science 273, 63-67.
    • (1996) Science , vol.273 , pp. 63-67
    • Smith, J.R.1    Pereira-Smith, O.M.2
  • 67
    • 0029313915 scopus 로고    scopus 로고
    • Memmalian DNA damage-inducible genes associated with growth arrest and apoptosis
    • Smith, L. M. and Fornace, Jr, A. J. (1996). Memmalian DNA damage-inducible genes associated with growth arrest and apoptosis. Mutat. Res. 340, 109-124.
    • (1996) Mutat. Res. , vol.340 , pp. 109-124
    • Smith, L.M.1    Fornace Jr., A.J.2
  • 68
    • 0023276258 scopus 로고
    • Cellular senescence revisited: A review
    • Stanulis-Praeger, B. M. (1987). Cellular senescence revisited: A review. Mech. Aging Dev. 38, 1-48.
    • (1987) Mech. Aging Dev. , vol.38 , pp. 1-48
    • Stanulis-Praeger, B.M.1
  • 69
    • 0002613038 scopus 로고
    • DNA repair and replication in aging organs and cells
    • ed. E. L. Schneider and C. E. Finch, New York: Van Nostrand Reinhold
    • Tice, R. R. and Setlow, R. B. (1985). DNA repair and replication in aging organs and cells. In Handbook of the Biology of Aging (ed. E. L. Schneider and C. E. Finch), pp. 173-224. New York: Van Nostrand Reinhold.
    • (1985) Handbook of the Biology of Aging , pp. 173-224
    • Tice, R.R.1    Setlow, R.B.2
  • 70
    • 0022628290 scopus 로고
    • Connective tissue biochemistry of the aging dermis. Age related alterations in collagen and elastin
    • Uitto, J. (1986). Connective tissue biochemistry of the aging dermis. Age related alterations in collagen and elastin. Dermatol. Clin. 4, 433-446.
    • (1986) Dermatol. Clin. , vol.4 , pp. 433-446
    • Uitto, J.1
  • 71
    • 0024445960 scopus 로고
    • Replicative senescence of human skin fibroblasts correlates with a loss of regulation and overexpression of collagenase activity
    • West, M. D., Pereira-Smith, O. M. and Smith, J. R. (1989). Replicative senescence of human skin fibroblasts correlates with a loss of regulation and overexpression of collagenase activity. Exp. Cell. Res. 184, 138-147.
    • (1989) Exp. Cell. Res. , vol.184 , pp. 138-147
    • West, M.D.1    Pereira-Smith, O.M.2    Smith, J.R.3
  • 72
    • 0024504721 scopus 로고
    • Regional localization of the TIMP gene on the human X chromosome. Extension of a conserved syntey and linkage group on proximal Xp
    • Willard, H. F., Durfy, S. J., Mahtani, M. M., Dorkins, H., Davies, K. E. and Williams, B. R. G. (1989). Regional localization of the TIMP gene on the human X chromosome. Extension of a conserved syntey and linkage group on proximal Xp. Hum. Genet. 81, 234-238.
    • (1989) Hum. Genet. , vol.81 , pp. 234-238
    • Willard, H.F.1    Durfy, S.J.2    Mahtani, M.M.3    Dorkins, H.4    Davies, K.E.5    Williams, B.R.G.6
  • 74
    • 0028427904 scopus 로고
    • UVA-induced autocrine stimulation of fibroblast derived collagenase/MMP-1 by interrelated loops of interleukin-1 and interleukin-6
    • Wlaschek, M., Heinen, G., Poswig, A., Schwarz, A., Krieg, T. and Scharffetter-Kochanek, K. (1994). UVA-induced autocrine stimulation of fibroblast derived collagenase/MMP-1 by interrelated loops of interleukin-1 and interleukin-6. Photochem. Photobiol. 59, 550-556.
    • (1994) Photochem. Photobiol. , vol.59 , pp. 550-556
    • Wlaschek, M.1    Heinen, G.2    Poswig, A.3    Schwarz, A.4    Krieg, T.5    Scharffetter-Kochanek, K.6


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