Effects of TAK-802, a novel acetylcholinesterase inhibitor, and tamsulosin, an α1-adrenoceptor antagonist, and their synergistic effects on the urodynamic characteristics in a guinea-pig model of functional bladder outlet obstruction

BJU International

Volumn 95, Issue 7, 2005, Pages 1071-1076

  Nagabukuro, Hiroshi ^a   Hashimoto, Tadatoshi ^a   Iwata, Masashi ^a   Doi, Takayuki ^a  

^a TAKEDA PHARMACEUTICAL COMPANY LIMITED   (Japan)

Author keywords

1 adrenoceptor antagonist; Acetylcholinesterase inhibitor; Guinea pig; TAK 802; Tamsulosin; Urodynamics

Indexed keywords

8 [3 [1 [(3 FLUOROPHENYL)METHYL] 4 PIPERIDINYL] 1 OXOPROPYL] 1,2,5,6 TETRAHYDRO 4H PYRROLO[3,2,1 I]QUINOLIN 4 ONE; ALPHA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; ALPHA 1 ADRENERGIC RECEPTOR STIMULATING AGENT; CHOLINESTERASE INHIBITOR; PHENYLEPHRINE; TAK 802; TAMSULOSIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLADDER NECK STENOSIS; BLADDER PRESSURE; CONTINUOUS INFUSION; CONTROLLED STUDY; CYSTOMETRY; DOSE RESPONSE; DRUG EFFECT; DRUG POTENCY; DRUG POTENTIATION; GUINEA PIG; MALE; MICTURITION; MICTURITION DISORDER; MONOTHERAPY; NONHUMAN; PRIORITY JOURNAL; PROSTATE HYPERTROPHY; URETHRA; URINARY TRACT DISEASE; URINE FLOW RATE; URODYNAMICS;

ACETYLCHOLINESTERASE; ADRENERGIC ALPHA-ANTAGONISTS; ANIMALS; CHOLINESTERASE INHIBITORS; DRUG SYNERGISM; DRUG THERAPY, COMBINATION; GUINEA PIGS; INFUSIONS, INTRAVENOUS; MALE; PROSTATIC HYPERPLASIA; PYRROLES; QUINOLONES; RECEPTORS, ADRENERGIC, BETA-1; SULFONAMIDES; URINARY BLADDER NECK OBSTRUCTION; URINARY RETENTION; URODYNAMICS;

EID: 18544389341     PISSN: 14644096     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1464-410X.2005.05469.x     Document Type: Article

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