Nuclear translocation of extracellular superoxide dismutase

Biochemical and Biophysical Research Communications

Volumn 296, Issue 1, 2002, Pages 54-61

  Ookawara, Tomomi ^a   Kizaki, Takako ^b   Takayama, Eiji ^c   Imazeki, Nobuo ^c   Matsubara, Osamu ^c   Ikeda, Yoshitaka ^d   Suzuki, Keiichiro ^a   Li Ji, Li ^e   Tadakuma, Takushi ^c   Taniguchi, Naoyuki ^d   Ohno, Hideki ^b  

^a HYOGO COLLEGE OF MEDICINE   (Japan)

^b KYORIN UNIVERSITY   (Japan)

^c NATIONAL DEFENSE MEDICAL COLLEGE   (Japan)

^d OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

^e UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Extracellular superoxide dismutase; Heparin binding domain; Nuclear localization signal; ROS; Secretion

Indexed keywords

GENOMIC DNA; HEPARIN BINDING PROTEIN; SIGNAL PEPTIDE; SUPEROXIDE DISMUTASE;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL TISSUE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL CULTURE; CELL STRAIN 3T3; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME LOCALIZATION; ENZYME RELEASE; GENE LOCATION; GENETIC TRANSFECTION; IMMUNOHISTOCHEMISTRY; INTRACELLULAR TRANSPORT; NONHUMAN; NUCLEOCYTOPLASMIC TRANSPORT; PRIORITY JOURNAL; PROTEIN DOMAIN; SITE DIRECTED MUTAGENESIS; WESTERN BLOTTING;

3T3 CELLS; ANIMALS; BLOTTING, WESTERN; CELL NUCLEUS; COS CELLS; HEPARIN; IMMUNOHISTOCHEMISTRY; MICE; NUCLEAR LOCALIZATION SIGNALS; PLASMIDS; PROTEIN TRANSPORT; SUPEROXIDE DISMUTASE;

EID: 18544372770     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-291X(02)00804-5     Document Type: Article

References (34)

1. Superoxide radical and superoxide dismutases
2. Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein)
3. Human copper-containing superoxide dismutase of high molecular weight
4. Extracellular superoxide dismutase: A regulator of nitric oxide bioavailability
5. Extracellular superoxide dismutase and other superoxide dismutase isoenzymes in tissues from nine mammalian species
6. Extracellular superoxide dismutase in human tissues and human cell lines
7. Heparin-affinity patterns and composition of extracellular superoxide dismutase in human plasma and tissues
8. Immunocytochemical localization of extracellular superoxide dismutase in human lung
9. Clinical significances of superoxide dismutases: Changes in aging diabetes, ischemia, and cancer
10. Phorbol ester induces manganese-superoxide dismutase in tumor necrosis factor-resistant cells
11. Increased glycated Cu,Zn-superoxide dismutase levels in erythrocytes of patients with insulin-dependent diabetes mellitus
12. Site-specific and random fragmentation of Cu,Zn-superoxide dismutase by glycation reaction. Implication of reactive oxygen species
13. Mouse extracellular superoxide dismutase: Primary structure tissue-specific gene expression chromosomal localization, and lung in situ hybridization
14. Binding of human extracellular superoxide dismutase C to sulphated glycosaminoglycans
15. The heparin-binding domain of extracellular superoxide dismutase C and formation of variants with reduced heparin affinity
16. The heparin binding site of human extracellular-superoxide dismutase
17. Tenfold increase in human plasma extracellular superoxide dismutase content caused by a mutation in heparin-binding domain
18. Tissue distribution of immunoreactive mouse extracellular superoxide dismutase
19. DNA cleavage induced by glycation of Cu,Zn-superoxide dismutase
20. Transcriptional activation of early-response genes by hydrogen peroxide in a mouse osteoblastic cell line
21. 2 and antioxidants have opposite effects on activation of NF-κB and AP-1 in intact cells: AP-1 as secondary antioxidant-responsive factor
22. Purification and subunit structure of extracellular superoxide dismutase from mouse lung tissue
23. Putative nuclear localization signals (NLS) in protein transcription factors
24. Transport of proteins and RNAs in and out of the nucleus
25. Translocation of bFGF to the nucleus is G1 phase cell cycle specific in bovine aortic endothelial cells
26. Retention of fibroblast growth factor 3 in the Golgi complex may regulate its export from cells
27. Competition between nuclear localization and secretory signals determines the subcellular fate of a single CUG-initiated form of FGF3
28. Cell cycle-dependent nuclear localization of exogenously added fibroblast growth factor-1 in BALB/c 3T3 and human vascular endothelial cells
29. Cupric ion/ascorbate/hydrogen peroxide-induced DNA damage: DNA-bound copper ion primarily induces base modifications
30. The antioxidant responsive element. Activation by oxidative stress and identification of the DNA consensus sequence required for functional activity
31. Functional antioxidant responsive elements
32. 2 and tumor necrosis factor-alpha activate intercellular adhesion molecule 1 (ICAM-1) gene transcription through distinct cis-regulatory elements within the ICAM-1 promoter
33. Oxygen and the control of gene expression
34. Role of oxidants and antioxidants in the induction of AP-1, NF-κB, and glutathione S-transferase gene expression