Durhamycin A, a potent inhibitor of HIV Tat transactivation

Journal of Natural Products

Volumn 65, Issue 8, 2002, Pages 1091-1095

  Jayasuriya, Hiranthi ^a   Lingham, Russell B ^a   Graham, Pia ^a   Quamina, Donette ^a   Herranz, Lucia ^b   Genilloud, Olga ^b   Gagliardi, Magda ^a   Danzeisen, Renee ^a   Tomassini, Joanne E ^a   Zink, Deborah L ^a   Guan, Ziqiang ^a   Singh, Sheo B ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b Medical affairs Merck sharp and Dohme ltd   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

DURHAMYCIN A; DURHAMYCIN B; MITHRAMYCIN; PROTEIN INHIBITOR; TRANSACTIVATOR PROTEIN; TRANSACTIVATOR PROTEIN INHIBITOR; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; DRUG ISOLATION; DRUG POTENCY; DRUG STRUCTURE; FERMENTATION; HUMAN; HUMAN CELL; IC 50; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE; STRUCTURE ANALYSIS; TRANSACTIVATION; VIRUS REPLICATION;

ANTI-HIV AGENTS; COSTA RICA; DRUG DESIGN; GENE EXPRESSION REGULATION, VIRAL; GENE PRODUCTS, TAT; HIV-1; HYDROLYSIS; INHIBITORY CONCENTRATION 50; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MOLECULAR STRUCTURE; PLICAMYCIN; PROTEIN BINDING; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 18544372619     PISSN: 01633864     EISSN: None     Source Type: Journal    
DOI: 10.1021/np010642f     Document Type: Article

References (12)