Adjuvant therapy in stage II colon cancer: Current approaches

Oncologist

Volumn 10, Issue 5, 2005, Pages 325-331

  Baddi, Lisa ^a   Benson III, A L ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Adjuvant chemotherapy; Colon cancer; Stage II

Indexed keywords

ANTINEOPLASTIC AGENT; FLUOROURACIL; FOLINIC ACID; LEVAMISOLE; OXALIPLATIN; SEMUSTINE; VINCRISTINE;

ADJUVANT CHEMOTHERAPY; CANCER STAGING; CANCER SURGERY; CANCER SURVIVAL; CLINICAL TRIAL; COLON CANCER; HIGH RISK PATIENT; HUMAN; PRIORITY JOURNAL; REVIEW;

ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CHEMOTHERAPY, ADJUVANT; COLONIC NEOPLASMS; HUMANS; NEOPLASM STAGING; RANDOMIZED CONTROLLED TRIALS;

EID: 18444408133     PISSN: 10837159     EISSN: None     Source Type: Journal    
DOI: 10.1634/theoncologist.10-5-325     Document Type: Review

References (28)

1. Jemal A, Tiwari RC, Murray T et al. Cancer statistics, 2004. CA Cancer J Clin 2004;54:8-29.
2. Nauta R, Stablein DM, Holyoke ED. Survival of patients with stage B2 colon carcinoma. The Gastrointestinal Tumor Study Group experience. Arch Surg 1989;124:180-182.
3. Moertel CG, Fleming TR, Macdonald JS et al. Levamisole and fluorouracil for adjuvant therapy of resected colon carcinoma. N Engl J Med 1990;322:352-358.
4. Andre T, Boni C, Mounedji-Boudiaf L et al. Oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment for colon cancer. N Engl J Med 2004;350:2343-2351.
5. Moertel CG, Fleming TR, Macdonald JS et al. Fluorouracil plus levamisole as effective adjuvant therapy after resection of stage III colon carcinoma: a final report. Ann Intern Med 1995;122:321-326.
6. Benson AB 3rd, Schrag D, Somerfield MR et al. American Society of Clinical Oncology recommendations on adjuvant chemotherapy for stage II colon cancer. J Clin Oncol 2004;22:3408-3419.
7. National Comprehensive Cancer Network. Available at http://www.nccn.org. Accessed March 16, 2005.
8. Engstrom PF, Benson AB 3rd, Saltz L, Colon Cancer Clinical Practice Guidelines in Oncology. JNCCN 2003;1:40-53.
9. Greene F, Page D, Fleming I et al., eds. Colon and Rectum. In: The AJCC Cancer Staging Handbook, Sixth Edition. New York: Springer, 2002:127-138.
10. Gill S, Loprinzi CL, Sargent DJ et al. Pooled analysis of fluorouracil-based adjuvant therapy for stage II and III colon cancer: who benefits and by how much? J Clin Oncol 2004;22:1797-1806.
11. Le Voyer TE, Sigurdson ER, Hanlon AL et al. Colon cancer survival is associated with increasing number of lymph nodes analyzed: a secondary survey of intergroup trial INT-0089. J Clin Oncol 2003;21:2912-2919.
12. Compton CC, Fielding LP, Burgart LJ et al. Prognostic factors in colorectal cancer. College of American Pathologists Consensus Statement 1999. Arch Pathol Lab Med 2000;124:979-994.
13. Haller DG, Catalano JS, Macdonald JS et al. Fluorouracil (FU), leucovorin and levamisole adjuvant therapy for colon cancer: five-year final report of INT-0089. Proc Am Soc Clin Oncol 1998;17:256a.
14. Wolmark N, Rockette H, Wickerham DL et al. Adjuvant therapy of Dukes' A, B, and C adenocarcinoma of the colon with portal-vein fluorouracil hepatic infusion: preliminary results of National Surgical Adjuvant Breast and Bowel Project Protocol C-02. J Clin Oncol 1990;8:1466-1475.
15. Wolmark N, Rockette H, Fisher B et al. The benefit of leucovorin-modulated fluorouracil as postoperative adjuvant therapy for primary colon cancer: results from National Surgical Adjuvant Breast and Bowel Project protocol C-03. J Clin Oncol 1993;11:1879-1887.
16. Wolmark N, Rockette H, Mamounas E et al. Clinical trial to assess the relative efficacy of fluorouracil and leucovorin, fluorouracil and levamisole, and fluorouracil, leucovorin, and levamisole in patients with Dukes' B and C carcinoma of the colon: results from National Surgical Adjuvant Breast and Bowel Project C-04. J Clin Oncol 1999;17:3553-3559.
17. Mamounas E, Wieand S, Wolmark N et al. Comparative efficacy of adjuvant chemotherapy in patients with Dukes' B versus Dukes' C colon cancer: results from four National Surgical Adjuvant Breast and Bowel Project adjuvant studies (C-01, C-02, C-03, and C-04). J Clin Oncol 1999;17:1349-1355.
18. International Multicentre Pooled Analysis of B2 Colon Cancer Trials (IMPACT B2) Investigators. Efficacy of adjuvant fluorouracil and folinic acid in B2 colon cancer. J Clin Oncol 1999;17:1356-1363.
19. Marsoni S. Efficacy of adjuvant fluorouracil and leucovorin in stage B2 and C colon cancer. International Multicenter Pooled Analysis of Colon Cancer Trials Investigators. Semin Oncol 2001;28(suppl 1):14-19.
20. Schrag D, Rifas-Shiman S, Saltz L et al. Adjuvant chemotherapy use for Medicare beneficiaries with stage II colon cancer. J Clin Oncol 2002;20:3999-4005.
21. Figueredo A, Charette ML, Maroun J et al. Adjuvant therapy for stage II colon cancer: a systematic review from the Cancer Care Ontario Program in Evidence-Based Care's Gastrointestinal Cancer Disease Site Group. J Clin Oncol 2004;22:3395-3407.
22. Hickish T, Boni C, Navarro M et al. FOLFOX4 as adjuvant treatment for stage II colon cancer: subpopulation data from the MOSAIC trial. Proc Am Soc Clin Oncol 2004;22:274s.
23. Gray RG, Barnwell J, Hills R et al. QUASAR: a randomized study of adjuvant chemotherapy vs observation including 3238 colorectal cancer patients. Proc Am Soc Clin Oncol 2004;22:245.
24. Horn A, Dahl O, Morild I. Venous and neural invasion as predictors of recurrence in rectal adenocarcinoma. Dis Colon Rectum 1991;34:798-804.
25. Knudsen JB, Nilsson T, Sprechler M et al. Venous and nerve invasion as prognostic factors in postoperative survival of patients with resectable cancer of the rectum. Dis Colon Rectum 1983;26:613-617.
26. Jen J, Kim H, Piantadosi S et al. Allelic loss of chromosome 18q and prognosis in colorectal cancer. N Engl J Med 1994;331:213-221.
27. Ribic CM, Sargent DJ, Moore MJ et al. Tumor microsatellite-instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancer. N Engl J Med 2003;349:247-257.
28. Mayo Clinic. Adjuvant Systemic Therapy Tools. http://www.mayoclinic.com/ calcs. Accessed March 9, 2005.