Acute exposure of human lung cells to 1,3-butadiene diepoxide results in G1 and G2 cell cycle arrest

Environmental and Molecular Mutagenesis

Volumn 45, Issue 4, 2005, Pages 354-364

  Schmiederer, Michael ^a   Knutson, Eugene ^a   Muganda, Perpetua ^b   Albrecht, Thomas ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

^b SOUTHERN UNIVERSITY   (United States)

Author keywords

1,3 Butadiene; Cell cycle; DNA damage; Environmental toxins; Fibroblasts; Industrial carcinogens

Indexed keywords

1,3 BUTADIENE DERIVATIVE; 1,3 BUTADIENE DIEPOXIDE; CARCINOGEN; INDUSTRIAL CHEMICAL; PROTEIN P21; PROTEIN P53; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL CYCLE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL DIVISION; CELL PROLIFERATION; CONTROLLED STUDY; DNA DAMAGE; ECOTOXICITY; EMBRYO; FIBROBLAST; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LUNG ALVEOLUS CELL; MITOSIS INDEX; NUCLEAR LOCALIZATION SIGNAL; SERUM;

ACUTE TOXICITY TESTS; CELL CYCLE; CELL CYCLE PROTEINS; CELL NUCLEUS; CELL PROLIFERATION; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DOSE-RESPONSE RELATIONSHIP, DRUG; EPOXY COMPOUNDS; FIBROBLASTS; G1 PHASE; G2 PHASE; HUMANS; LUNG; MITOTIC INDEX; MUTAGENS; TUMOR SUPPRESSOR PROTEIN P53;

BOVINAE; RODENTIA;

EID: 18444386872     PISSN: 08936692     EISSN: None     Source Type: Journal    
DOI: 10.1002/em.20099     Document Type: Article

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