Development of a quality control method for the characterization of oligonucleotides by capillary zone electrophoresis-electrospray ionization-quadrupole time of flight-mass spectrometry

Electrophoresis

Volumn 26, Issue 7-8, 2005, Pages 1412-1423

  Willems, An V ^a   Deforce, Dieter L ^a   Van Peteghem, Carlos H ^a   Van Bocxlaer, Jan F ^a  

^a GHENT UNIVERSITY   (Belgium)

Author keywords

Capillary zone electrophoresis; Electrospray ionization mass spectrometry; Oligonucleotides; Quadrupole time of flight; Quality control

Indexed keywords

CAPILLARY ELECTROPHORESIS; ELECTROSPRAY IONIZATION; MASS SPECTROMETRY; METAL IONS; NITROGEN COMPOUNDS; OLIGONUCLEOTIDES; POSITIVE IONS; QUALITY ASSURANCE;

% REDUCTIONS; CAPILLARY-ZONE ELECTROPHORESIS; CONTROL METHODS; ELECTROSPRAY IONIZATION MASS SPECTROMETRY; ELECTROSPRAY IONIZATION-QUADRUPOLE TIME-OF-FLIGHT MASS SPECTROMETRY; MODEL COMPOUND; NEGATIVE ELECTROSPRAY IONIZATIONS; QUADRUPOLE/TIME OF FLIGHTS; SPECTRA'S; SPECTROMETRIC METHODS;

QUALITY CONTROL;

AMMONIA; CARBONIC ACID; CATION; CYCLOHEXANEDIAMINETETRAACETIC ACID; IMIDAZOLE; METAL ION; OLIGONUCLEOTIDE; PIPERIDINE;

ANALYTICAL ERROR; ARTICLE; CAPILLARY ZONE ELECTROPHORESIS; CHEMICAL BINDING; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ELECTROPHORESIS; ELECTROSPRAY MASS SPECTROMETRY; IONIZATION; MOLECULAR WEIGHT; ONLINE ANALYSIS; PH; PROTEIN ANALYSIS; PROTEIN SYNTHESIS; QUALITY CONTROL; SAMPLING; SENSITIVITY ANALYSIS; SEPARATION TECHNIQUE; SIGNAL DETECTION; TIME OF FLIGHT MASS SPECTROMETRY;

EID: 18444383397     PISSN: 01730835     EISSN: None     Source Type: Journal    
DOI: 10.1002/elps.200406201     Document Type: Article

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