Changing the efficiency and specificity of the esterase activity of human carbonic anhydrase II by site-specific mutagenesis

European Journal of Biochemistry

Volumn 262, Issue 2, 1999, Pages 516-521

  Elleby, Björn ^b   Sjöblom, Björn ^b   Lindskog, Sven ^a  

^a UMEÅ UNIVERSITY   (Sweden)

^b NONE

Author keywords

Carbonic anhydrase; Esterase activity; Mutagenesis; Substrate specificity

Indexed keywords

ACETIC ACID DERIVATIVE; CARBONATE DEHYDRATASE II; ESTERASE;

ARTICLE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME KINETICS; ENZYME SPECIFICITY; HYDROLYSIS; MOLECULAR MODEL; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; STRUCTURE ANALYSIS;

CARBONIC ANHYDRASES; ESTERASES; HUMANS; MODELS, CHEMICAL; MUTAGENESIS, SITE-DIRECTED; SUBSTRATE SPECIFICITY;

EID: 1842871152     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.1999.00400.x     Document Type: Article

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