Binding of [99mTc]chondroitin sulfate to scavenger receptors on human chondrocytes as compared to binding of oxidized [125I]LDL on human macrophages

Journal of Receptors and Signal Transduction

Volumn 22, Issue 1-4, 2002, Pages 459-470

  Sobal, G ^a   Sinzinger, H ^a  

^a UNIVERSITY OF VIENNA   (Austria)

Author keywords

Atherosclerosis; Chondroitin sulfate; LDL; LDL modification; Scavenger receptor CD36

Indexed keywords

CALCIUM DERIVATIVE; CD36 ANTIGEN; CHONDROITIN SULFATE; IODINE 125; LIPOPOLYSACCHARIDE; LIPOPROTEIN; OXIDIZED LOW DENSITY LIPOPROTEIN; PROTEOGLYCAN; SCAVENGER RECEPTOR; TECHNETIUM 99M; IMMUNOGLOBULIN RECEPTOR; LIPOPROTEIN RECEPTOR; LOW DENSITY LIPOPROTEIN; MEMBRANE PROTEIN; RADIOPHARMACEUTICAL AGENT; SCARB1 PROTEIN, MOUSE; SCAVENGER RECEPTOR B; TECHNETIUM COMPLEX; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

ATHEROSCLEROSIS; BINDING AFFINITY; BINDING SITE; CARTILAGE CELL; CELL ACTIVATION; CONFERENCE PAPER; DIALYSIS; HUMAN; HUMAN CELL; MACROPHAGE; MONOCYTE; OSTEOARTHRITIS; ADULT; ARTICLE; CELL CULTURE; CELL MEMBRANE; COMPARATIVE STUDY; FEMALE; IN VITRO STUDY; MALE; METABOLISM; MIDDLE AGED; OXIDATION REDUCTION REACTION;

ADULT; ANTIGENS, CD36; CELL MEMBRANE; CELLS, CULTURED; CHONDROCYTES; CHONDROITIN SULFATES; FEMALE; HUMANS; LIPOPROTEINS, LDL; MACROPHAGES; MALE; MEMBRANE PROTEINS; MIDDLE AGED; ORGANOTECHNETIUM COMPOUNDS; OXIDATION-REDUCTION; PROTEOGLYCANS; RADIOPHARMACEUTICALS; RECEPTORS, IMMUNOLOGIC; RECEPTORS, LIPOPROTEIN; RECEPTORS, SCAVENGER; SCAVENGER RECEPTORS, CLASS B; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

EID: 1842866806     PISSN: 10799893     EISSN: 15324281     Source Type: Journal    
DOI: 10.1081/RRS-120014614     Document Type: Conference Paper

References (33)

1. Endemann, G.; Stanton, L.; Madden, K.; Bryant, K.; White, R.T.; Protter, A. CD36 is a Receptor for Oxidized Low Density Lipoprotein. J. Biol. Chem. 1993, 268, 4569-4572.
2. Nicholson, A.S.; Pearce, F.A.; Silverstein, R. Oxidized LDL Binds to CD36 on Human Monocyte-Derived Macrophages and Transfected Cell Lines. Evidence Implicated the Lipid Moiety of the Lipoprotein as the Binding Site. Atheroscler. Thromb. Vasc. Biol. 1995, 15, 269-275.
3. Witztum, J.L.; Steinberg, D. Role of Oxidized Low Density Lipoprotein in Atherogenesis. J. Clin. Invest. 1991, 88, 1785-1792.
4. Ross, R. The Pathogenesis of Atherosclerosis: A Perspective for the 1990s. Nature 1993, 362, 801-808.
5. Brown, M.S.; Goldstein, J.L. A Receptor-Mediated Pathway for Cholesterol Homeostasis. Science 1986, 232, 34-47.
6. Steinberg, D.; Parthasarathy, S.; Carew, T.E.; Ho, Y.K.; Witztum, J.L. Beyond Cholesterol: Modification that Increases its Atherogenicity. New Engl. J. Med. 1989, 320, 915-924.
7. Henriksen, T.; Mahony, E.M.; Steinberg, D. Enhanced Macrophage Degradation of Biologically Modified Low-Density Lipoprotein. Arteriosclerosis 1983, 3, 149-159.
8. Tontonoz, P.; Nagy, L. Regulation of Macrophage Gene Expression by Peroxisome-Proliferator-Activated Receptor Gamma: Implications for Cardiovascular Disease. Curr. Opin. Lipidol. 1999, 10, 485-490.
9. Tontonoz, P.; Nagy, L.; Alvarez, J.G.; Thomazy, V.A.; Evans, R.M. PPAR Gamma Promotes Monocyte-Macrophage Differentiation and Uptake of Oxidized LDL. Cell 1998, 93, 241-252.
10. Bassleer, C.T.; Combal, J.P.A.; Bougaret, S.; Malaise, M. Effects of Chondroitin Sulfate and Interleukin-1β on Human Articular Chondrocytes Cultivated in Clusters. Osteoarthr. Cartilage 1998, 6, 196-204.
11. Havel, R.J.; Eder, H.A.; Bragdon, J.H. The Distribution and Chemical Composition of Ultracentrifugally Separated Lipoproteins in Human Serum. J. Clin. Invest. 1985, 34, 1345-1353.
12. Esterbauer, H.; Striegl, G.; Puhl, H.; Rotheneder, M. Continuous Monitoring of In Vitro Oxidation of Human Low-Density Lipoproteins. Free Rad. Res Comm. 1981, 6, 67-75.
13. Buege, J.A.; Aust, S.D. Lactoperoxidase-Catalyzed Lipid Peroxidation of Microsomal and Artificial Membranes. Biochim. Biophys. Acta 1976, 444, 192-201.
14. Mc Conahey, P.J.; Dixon, F.J. A Method of Trace Iodination of Proteins for Immunologic Studies. Int. Arch. Allergy 1966, 29, 185-187.
15. Brown, M.S.; Goldstein, J.L. Lipoprotein Metabolism in the Macrophage: Implications for Cholesterol Deposition in Atherosclerosis. Annu. Rev. Biochem. 1983, 52, 223-261.
16. Freeman, M.; Ekkel, Y.; Rohrer, L.; Penman, M.; Freedman, N.J.; Chisolm, G.M.; Krieger, M. Expression of Type I and Type II Bovine Scavenger Receptors in Chinese Hamster Ovary Cells. Proc. Natl. Acad. Sci. USA 1991, 88, 4931-4935.
17. Krieger, M.; Hertz, J. Structures and Functions of Multiligand Lipoprotein Receptors: Macrophage Scavenger Receptors and LDL Receptor-Related Protein (LRP). Annu. Rev. Biochem. 1994, 63, 601-637.
18. Sparrow, C.P.; Parthasarathy, S.; Steinberg, D. A Macrophage Receptor that Recognizes Oxidized Low-Density Lipoprotein but not Acetylated Low-Density Lipoprotein. J. Biol. Chem. 1989, 264, 2599-2604.
19. Camejo, G.; Rosengren, B.; Olson, U.; Lopez, F.; Olofson, S.O.; Westerlund, C.; Bondjers, G. Molecular Basis of the Association of Arterial Proteoglycans with Low Density Lipoproteins: Its Effect on the Structure of the Lipoprotein Particle. Eur. Heart J. 1990, 11 (Suppl. E), 164-173.
20. Arai, H.; Kita, T.; Yokode, M.; Narumiya, S.; Kawai, C. Multiple Receptors for Modified Low-Density Lipoprotein in Mouse Peritoneal Macrophages: Different Uptake Mechanism for Acetylated and Oxidized Low-Density Lipoprotein. Biochem. Biophys. Res. Commun. 1989, 150, 1375-1382.
21. Van Berkel, T.J.C.; de Rijke, Y.B.; Kruijt, K. Different Fate In Vivo of Oxidatively Modified Low-Density Lipoprotein and Acetylated Low-Density Lipoprotein in Rats.: Recognition by Various Scavenger Receptors on Kupfer and Endothelial Liver Cells. J. Biol. Chem. 1991, 266, 2282-2289.
22. Goldstein, J.L.; Ho, Y.K.; Basu, S.K.; Brown, M.S. Binding Site on Macrophages that Mediates Uptake and Degradation of Acetylated Low Density Lipoprotein, Producing Massive Cholesterol Deposition. Proc. Natl. Acad. Sci. USA 1979, 76, 333-337.
23. Bordji, K.; Grillasca, J.P.; Gouze, J.N.; Magdalou, J.; Schohn, H.; Keller, J.M.; Bianchi, A.; Dauca, M.; Netter, P.; Terlain, B. Evidence for the Presence of Peroxisome Proliferator-Activated Receptor (PPAR) Alpha and Gamma and Retinoid Z Receptor in Cartilage. PPARgamma Activation Modulates the Effects of Interleukin-1Beta on Rat Chondrocytes. J. Biol. Chem. 2000, 275, 12243-12250.
24. Fahmi, H.; Di Battista, J.A.; Pelletier, J.P.; Mineau, E.; Ranger, P.; Martel-Pelletier, J. Peroxisome Proliferator-Activated Receptor Gamma Activators Inhibit Interleukin-1Beta-Induced Nitric Oxide and Matrix Metalloproteinase 13 Production in Human Chondrocytes. Arthritis Rheum. 2001, 44, 595-607.
25. Ishihara, M.; Fedarko, N.S.; Conrad, H.E. Involvement of Phosphatidylinositol and Insulin in the Coordinate Regulation of Proteoheparan Sulfate Metabolism and Hepatocyte Growth. J. Biol. Chem. 1987, 262, 4708-4716.
26. Palmieri, L.; Conte, A.; Giovannini, L.; Lualdi, P.; Ronca, G. Metabolic Fate of Exogenous Chondroitin Sulfate in the Experimental Animal. Arzneimittel Forsch. Drug Res. 1990, 40, 319-323.
27. Staprans, I.; Felts, J.M. Isolation and Characterization of Glycosaminoglycans in Human Plasma. J. Clin. Invest. 1985, 76, 1984-1991.
28. Kaplan, M.; Aviram, M. Macrophage Plasma Membrane Chondroitin Sulfate Proteoglycan Binds Oxidized Low-Density Lipoprotein. Atherosclerosis 2000, 149, 5-17.
29. Camejo, G.; Rosengren, B.; Olson, U.; Lopez, F.; Olofson, S.O.; Westerlund, C.; Bondjers, G. Molecular Basis of the Association of Arterial Proteoglycans with Low Density Lipoproteins. Its Effect on The Structure of the Lipoprotein Particle. Eur. Heart J. 1990, 11 (Suppl. E), 164-173.
30. Ronca, F.; Palmieri, L.; Pinicucci, P.; Ronca, G. Anti-Inflammatory Activity of Chondroitin Sulfate. Osteoarthr Cartilage 1998, 6S A, 14-21.
31. Pfander, D.; Cramer, T.; Deuerling, D.; Weseloh, G.; Swoboda, B. Expression of Thrombospondin-1 and its Receptor CD36 in Human Osteoarthritic Cartilage. Ann. Rheum. Dis. 2000, 59, 448-454.
32. Vijayagopal, P.; Srinivasan, S.R.; Radhakrishnamurthy, B.; Berenson, G.S. Human Monocyte-Derived Macrophages Bind Low-Density-Lipoprotein-Proteoglycan Complexes by a Receptor Different from the Low-Density-Lipoprotein Receptor. Biochem. J. 1993, 289, 837-844.
33. Kaplan, M.; Williams, K.J.; Mandel, H.; Aviram, M. Role of Macrophage Glycosaminoglycans in the Cellular Catabolism of Oxidized LDL by Macrophages. Arterioscler. Thromb. Vasc. Biol. 1998, 18, 542-553.