A proximal tissue-specific module and a distal negative regulatory module control apolipoprotein(a) gene transcription

Biochemical Journal

Volumn 379, Issue 1, 2004, Pages 151-159

  Negi, Sarita ^a   Singh, Saurabh K ^a,b   Pati, Nirupma ^a,c   Handa, Vikas ^a,d   Chauhan, Ruchi ^a   Pati, Uttam ^a  

^a JAWAHARLAL NEHRU UNIVERSITY   (India)

^b INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY ICGEB   (India)

^c JUSTUS LIEBIG UNIVERSITY   (Germany)

^d NATIONAL INSTITUTE OF IMMUNOLOGY   (India)

Author keywords

Apolipoprotein(a); GATA binding protein 4 (GATA4); Hepatocyte nuclear factor (HNF3); Negative regulatory module; Tissue specific regulatory element; Transcriptional regulation

Indexed keywords

CELLS; GENES; LIPIDS; PLASMA STABILITY; PROTEINS; RISK MANAGEMENT; TISSUE;

HELA CELL; LIPOPROTEINS; MYOCARDIAL INFARCTION;

BIOCHEMISTRY;

APOLIPOPROTEIN A; HEPATOCYTE NUCLEAR FACTOR 3; NUCLEOTIDE; TRANSCRIPTION FACTOR GATA 4;

ARTICLE; CELL STRAIN HEPG2; GENE ACTIVATION; GENE CONTROL; GENE REPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; TISSUE SPECIFICITY; TRANSCRIPTION INITIATION;

APOLIPOPROTEINS A; CARCINOMA, HEPATOCELLULAR; CARDIOVASCULAR DISEASES; CELL LINE, TUMOR; GENE EXPRESSION REGULATION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, REPORTER; GENETIC PREDISPOSITION TO DISEASE; HELA CELLS; HUMANS; LIVER NEOPLASMS; NEOPLASM PROTEINS; ORGAN SPECIFICITY; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; REGULATORY SEQUENCES, NUCLEIC ACID; REPETITIVE SEQUENCES, NUCLEIC ACID; REPRESSOR PROTEINS; RISK FACTORS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSFECTION;

EID: 1842866204     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20030985     Document Type: Article

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