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Volumn 18, Issue 2, 2004, Pages 113-118

Antisense therapy specific to mutated K-ras gene in hamster pancreatic cancer model. Can it inhibit the growth of 5-FU and MMC-resistant metastatic anb remetastic cell lines?

Author keywords

Antisense oligonucleotides; Drug resistance; K ras point mutation; Metastasis; Pancreatic cancer; Syrian golden hamsters

Indexed keywords

AGAROSE; ANTISENSE OLIGONUCLEOTIDE; FLUOROURACIL; MITOMYCIN C;

EID: 1842841750     PISSN: 0258851X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (9)

References (33)
  • 2
    • 0038650956 scopus 로고    scopus 로고
    • An introduction to pancreatic adenocarcinoma genetics, pathology, and therapy
    • Kern SE, Hruban RH, Hidalgo M and Yeo CJ: An introduction to pancreatic adenocarcinoma genetics, pathology, and therapy. Cancer Biol Ther 1: 607-613, 2002.
    • (2002) Cancer Biol. Ther. , vol.1 , pp. 607-613
    • Kern, S.E.1    Hruban, R.H.2    Hidalgo, M.3    Yeo, C.J.4
  • 3
    • 85069427865 scopus 로고    scopus 로고
    • US Mortality Public Use Date Tapes 1960-1996
    • US Mortality Volumes 1930-1959. National Center for Health Statistics. Centers for Disease Control and Prevention URL
    • US Mortality Public Use Date Tapes 1960-1996. US Mortality Volumes 1930-1959. National Center for Health Statistics. Centers for Disease Control and Prevention, 1999. URL:http://www.acrs.org
    • (1999)
  • 4
    • 0035405115 scopus 로고    scopus 로고
    • Advances in the surgical management of pancreatic cancer
    • Spanknebel K and Conlon KC: Advances in the surgical management of pancreatic cancer. Cancer J 7: 312-323, 2001.
    • (2001) Cancer J. , vol.7 , pp. 312-323
    • Spanknebel, K.1    Conlon, K.C.2
  • 5
    • 0029125820 scopus 로고
    • K-ras mutations and pancreatic adenocarcinoma
    • Caldas C and Kern SE: K-ras mutations and pancreatic adenocarcinoma. Int J Pancreatol 18: 1-6, 1995.
    • (1995) Int. J. Pancreatol. , vol.18 , pp. 1-6
    • Caldas, C.1    Kern, S.E.2
  • 6
    • 0029132150 scopus 로고
    • Molecular genetics of exocrine pancreatic neoplasms
    • Hahn SA and Kern SE: Molecular genetics of exocrine pancreatic neoplasms. Surg Clin North Am 75: 857-869, 1995.
    • (1995) Surg. Clin. North Am. , vol.75 , pp. 857-869
    • Hahn, S.A.1    Kern, S.E.2
  • 7
    • 0033953188 scopus 로고    scopus 로고
    • Molecular biology of pancreatic cancer: Oncogenes, tumor suppressor genes, growth factors and their receptors from a clinical perspective
    • Sakorafas GH, Tsiotou AG and Tsiotou GG: Molecular biology of pancreatic cancer: oncogenes, tumor suppressor genes, growth factors and their receptors from a clinical perspective. Cancer Treat Rev 26: 29-52, 2000.
    • (2000) Cancer Treat. Rev. , vol.26 , pp. 29-52
    • Sakorafas, G.H.1    Tsiotou, A.G.2    Tsiotou, G.G.3
  • 8
    • 0033872039 scopus 로고    scopus 로고
    • Genetic progression in the pancreatic ducts
    • Hruban RH, Wilentz Re and Kern SE: Genetic progression in the pancreatic ducts. Am J Pathol 156: 1821-1825, 2000.
    • (2000) Am. J. Pathol. , vol.156 , pp. 1821-1825
    • Hruban, R.H.1    Wilentz Re2    Kern, S.E.3
  • 9
    • 0033835421 scopus 로고    scopus 로고
    • The importance of being K-ras
    • Ellis CA and Clark G: The importance of being K-ras. Cell Sign 12:425-434, 2000.
    • (2000) Cell Sign. , vol.12 , pp. 425-434
    • Ellis, C.A.1    Clark, G.2
  • 11
    • 0026808451 scopus 로고
    • K-ras mutation is an early event in pancreatic duct carcinogenesis in the Syrian golden hamsters
    • Cerny WL, Mangold KA and Scarpelli DG: K-ras mutation is an early event in pancreatic duct carcinogenesis in the Syrian golden hamsters. Cancer Res 52: 4507-4513, 1992.
    • (1992) Cancer Res. , vol.52 , pp. 4507-4513
    • Cerny, W.L.1    Mangold, K.A.2    Scarpelli, D.G.3
  • 14
    • 0031944562 scopus 로고    scopus 로고
    • Mechanistic analysis of pancreatic ductal carcinogenesis in hamsters
    • Konishi Y, Tsutsumi M and Tsujiuchi T: Mechanistic analysis of pancreatic ductal carcinogenesis in hamsters. Pancreas 16: 300-306, 1998.
    • (1998) Pancreas , vol.16 , pp. 300-306
    • Konishi, Y.1    Tsutsumi, M.2    Tsujiuchi, T.3
  • 15
    • 0027978836 scopus 로고
    • In vitro carcinogenesis of hamster pancreatic duct cells: Cellular and molecular alterations
    • Mangold KA, Hubchak S, Mangino MM, Laconi S and Scarpelli DG: In vitro carcinogenesis of hamster pancreatic duct cells: cellular and molecular alterations. Carcinogenesis 15: 1979-1984, 1994.
    • (1994) Carcinogenesis , vol.15 , pp. 1979-1984
    • Mangold, K.A.1    Hubchak, S.2    Mangino, M.M.3    Laconi, S.4    Scarpelli, D.G.5
  • 16
    • 0029041373 scopus 로고
    • Multiple genetic alterations in hamster pancreatic ductal adenocarcinomas
    • Chang KW, Laconi S, Mangold KA, Hubchak S and Scarpelli DG: Multiple genetic alterations in hamster pancreatic ductal adenocarcinomas. Cancer Res 55: 2560-2568, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 2560-2568
    • Chang, K.W.1    Laconi, S.2    Mangold, K.A.3    Hubchak, S.4    Scarpelli, D.G.5
  • 17
    • 0033995159 scopus 로고    scopus 로고
    • Homologous orthotopic implantation models of pancreatic ductal cancer in Syrian golden hamsters: Which is better for metastasis research--cell implantation or tissue implantation?
    • Morioka CY, Saito S, Ohzawa K and Watanabe A: Homologous orthotopic implantation models of pancreatic ductal cancer in Syrian golden hamsters: which is better for metastasis research--cell implantation or tissue implantation? Pancreas 20: 152-157, 2000.
    • (2000) Pancreas , vol.20 , pp. 152-157
    • Morioka, C.Y.1    Saito, S.2    Ohzawa, K.3    Watanabe, A.4
  • 18
    • 0034445619 scopus 로고    scopus 로고
    • Curative resection of orthotopically implanted pancreatic cancer in Syrian golden hamsters
    • Morioka CY, Saito S, Kita K and Watanabe A: Curative resection of orthotopically implanted pancreatic cancer in Syrian golden hamsters. Int J Pancreatol 28: 207-213, 2000.
    • (2000) Int. J. Pancreatol. , vol.28 , pp. 207-213
    • Morioka, C.Y.1    Saito, S.2    Kita, K.3    Watanabe, A.4
  • 19
    • 3242675054 scopus 로고    scopus 로고
    • Subcutaneously inoculated cells and implanted pancreatic cancer tissue show different patterns of metastases in Syrian golden hamsters
    • Morioka CY, Saito S, Ohzawa K Asano S, Hibino Y, Nakada Y, Kita KI and Watanabe A: Subcutaneously inoculated cells and implanted pancreatic cancer tissue show different patterns of metastases in Syrian golden hamsters. JOP 1: 183-90, 2000.
    • (2000) JOP , vol.1 , pp. 183-190
    • Morioka, C.Y.1    Saito, S.2    Ohzawa, K.3    Asano, S.4    Hibino, Y.5    Nakada, Y.6    Kita, K.I.7    Watanabe, A.8
  • 20
    • 0028145748 scopus 로고
    • Intrinsic or acquired drug resistance and metastasis: Are they linked phenotypes?
    • Kerbel RS, Kobayashi H and Graham CH: Intrinsic or acquired drug resistance and metastasis: are they linked phenotypes? J Cell Biochem 56: 37-47, 1994.
    • (1994) J. Cell Biochem. , vol.56 , pp. 37-47
    • Kerbel, R.S.1    Kobayashi, H.2    Graham, C.H.3
  • 21
    • 0033052436 scopus 로고    scopus 로고
    • Critical determinants of cancer metastasis: Rationale for therapy
    • Fidler IJ: Critical determinants of cancer metastasis: rationale for therapy. Cancer Chemother Pharmacol 43: S3-10, 1999.
    • (1999) Cancer Chemother. Pharmacol. , vol.43
    • Fidler, I.J.1
  • 23
    • 0030710098 scopus 로고    scopus 로고
    • Supression of K-ras P21 levels leading to growth inhibition of pancreatic cancer cell lines with K-ras mutations but not those without K-ras mutation
    • Aoki K, Yoshida T, Matsumoto N, Ide H, Sugiyama T and Terada M: Supression of K-ras P21 levels leading to growth inhibition of pancreatic cancer cell lines with K-ras mutations but not those without K-ras mutation. Mol Carcinog 20: 251-258, 1997.
    • (1997) Mol. Carcinog. , vol.20 , pp. 251-258
    • Aoki, K.1    Yoshida, T.2    Matsumoto, N.3    Ide, H.4    Sugiyama, T.5    Terada, M.6
  • 24
    • 0029124127 scopus 로고
    • Liposome-mediated in vivo gene transfer of antisense K-ras construct inhibits pancreatic tumor dissemination in the murine peritoneal cavity
    • Aoki K, Yoshida T, Sugimura T and Terada M: Liposome-mediated in vivo gene transfer of antisense K-ras construct inhibits pancreatic tumor dissemination in the murine peritoneal cavity. Cancer Res 55: 3810-3816, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 3810-3816
    • Aoki, K.1    Yoshida, T.2    Sugimura, T.3    Terada, M.4
  • 25
    • 0033521860 scopus 로고    scopus 로고
    • Growth inhibition of human pancreatic cancer cell lines by anti-sense oligonucleotides specific to mutated K-ras genes
    • Kita K, Saito S, Morioka CY and Watanabe A: Growth inhibition of human pancreatic cancer cell lines by anti-sense oligonucleotides specific to mutated K-ras genes. Int J Cancer 80: 553-558, 1999.
    • (1999) Int. J. Cancer , vol.80 , pp. 553-558
    • Kita, K.1    Saito, S.2    Morioka, C.Y.3    Watanabe, A.4
  • 26
    • 0035553610 scopus 로고    scopus 로고
    • Antisense oligonucleotides specific to mutated K-ras genes inhibit invasiveness of human pancreatic cancer cell lines
    • Nakada Y, Saito S, Ohzawa & Morioka CY, Kita K. Minemura M, Takahara T and Watanabe A: Antisense oligonucleotides specific to mutated K-ras genes inhibit invasiveness of human pancreatic cancer cell lines. Pancreatology 1: 314-319, 2001.
    • (2001) Pancreatology , vol.1 , pp. 314-319
    • Nakada, Y.1    Saito, S.2    Ohzawa, A.3    Morioka, C.Y.4    Kita, K.5    Minemura, M.6    Takahara, T.7    Watanabe, A.8
  • 27
    • 0023915635 scopus 로고
    • Establishment and characterization of a cultured cell line derived from nitrosamine-induced pancreatic ductal adenocarcinoma in Syrian golden hamsters
    • Saito S, Nishimura N, Kubota Y, Yamazaki K, Shibuya T and Sasaki H: Establishment and characterization of a cultured cell line derived from nitrosamine-induced pancreatic ductal adenocarcinoma in Syrian golden hamsters. Gastroenterol Jpn 23: 183-194, 1988.
    • (1988) Gastroenterol. Jpn. , vol.23 , pp. 183-194
    • Saito, S.1    Nishimura, N.2    Kubota, Y.3    Yamazaki, K.4    Shibuya, T.5    Sasaki, H.6
  • 28
    • 0033917529 scopus 로고    scopus 로고
    • "Return trip" metastases from the liver to the pancreas in Syrian golden hamsters
    • Morioka CY, Saito S and Watanabe A: "Return trip" metastases from the liver to the pancreas in Syrian golden hamsters. In Vivo 14: 467-469, 2000.
    • (2000) In Vivo , vol.14 , pp. 467-469
    • Morioka, C.Y.1    Saito, S.2    Watanabe, A.3
  • 29
    • 0028000463 scopus 로고
    • Evaluation of MTT assay in agarose for chemosensitivity testing of human cancers: Comparison with MTT assay
    • Abe R, Ueo H and Akiyoshi T: Evaluation of MTT assay in agarose for chemosensitivity testing of human cancers: comparison with MTT assay. Oncology 51: 416-425, 1994.
    • (1994) Oncology , vol.51 , pp. 416-425
    • Abe, R.1    Ueo, H.2    Akiyoshi, T.3
  • 30
    • 0036972017 scopus 로고    scopus 로고
    • Resection for pancreatic cancer in the new millennium
    • Andren-Sandberg A and Neoptolemos JP: Resection for pancreatic cancer in the new millennium. Pancreatology 2: 431-439, 2002.
    • (2002) Pancreatology , vol.2 , pp. 431-439
    • Andren-Sandberg, A.1    Neoptolemos, J.P.2
  • 33
    • 0036991860 scopus 로고    scopus 로고
    • Future directions in the treatment of pancreatic cancer
    • Haller DG: Future directions in the treatment of pancreatic cancer. Semin Oncol 29: 31-39, 2002.
    • (2002) Semin. Oncol. , vol.29 , pp. 31-39
    • Haller, D.G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.