In vitro and in vivo degradation of bioabsorbable PLLA spinal fusion cages

Journal of Biomedical Materials Research

Volumn 63, Issue 6, 2002, Pages 752-759

  Van Dijk, M ^a   Tunc, D C ^b   Smit, T H ^a   Higham, P ^b   Burger, E H ^c   Wuisman, P I J M ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b STRYKER ORTHOPAEDICS   (United States)

^c VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

High load bearing; In vitro and in vivo degradation; Lumbar interbody fusion; Poly L lactic acid; Spinal fusion cage

Indexed keywords

ABSORPTION; BONE; DEGRADATION; GRAFTS; IMPLANTS (SURGICAL); STRENGTH OF MATERIALS; VISCOSITY;

SPINAL MOTION;

BIOMATERIALS;

POLYLACTIC ACID; BIOMATERIAL; LACTIC ACID; POLYMER;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTHRODESIS; ARTICLE; BIOMECHANICS; BONE GRAFT; CONTROLLED STUDY; CRYSTALLIZATION; DEGRADATION; ENANTIOMER; FEMALE; GEOMETRY; GOAT; IMPLANT; LUMBAR SPINE; MECHANICAL STRESS; NONHUMAN; SPINE FUSION; SPINE SURGERY; TISSUE REACTION; VISCOSITY; WEIGHT BEARING; ABSORPTION; ANIMAL; BIOREMEDIATION; DIFFUSION CHAMBER; IN VITRO STUDY; INSTRUMENTATION; LUMBAR VERTEBRA; MATERIALS TESTING; METABOLISM; TIME;

ABSORPTION; ANIMALS; BIOCOMPATIBLE MATERIALS; BIODEGRADATION, ENVIRONMENTAL; DIFFUSION CHAMBERS, CULTURE; FEMALE; GOATS; LACTIC ACID; LUMBAR VERTEBRAE; MATERIALS TESTING; MODELS, ANIMAL; POLYMERS; SPINAL FUSION; TIME FACTORS;

EID: 1842836455     PISSN: 00219304     EISSN: None     Source Type: Journal    
DOI: 10.1002/jbm.10466     Document Type: Article

References (45)

1. Bagby GW. Arthrodesis by the distraction-compression method using a stainless steel implant. Orthopedics 1988;11:931-934.
2. Ray CD. Threaded titanium cages for lumbar interbody fusions. Spine 1997;22:667-679.
3. Agazzi S, Reverdin A, May D. Posterior lumbar interbody fusion with cages: An independent review of 71 cases. J Neurosurg 1999;91:186-192.
4. Brantigan JW, Steffee AD. A carbon fiber implant to aid interbody lumbar fusion. Two-year clinical results in the first 26 patients. Spine 1993;18:2106-2107.
5. McAfee PC, Regan JJ, Geis WP, Fedder IL. Minimally invasive anterior retroperitoneal approach to the lumbar spine. Emphasis on the lateral BAK. Spine 1998;23:1476-1484.
6. Kuslich SD, Ulstrom CL, Griffith SL, Ahern JW, Dowdle JD. The Bagby and Kuslich method of lumbar interbody fusion. History, techniques, and 2-year follow-up results of a United States prospective, multicenter trial. Spine 1998;23:1267-1278.
7. Brantigan JW. Pseudarthrosis rate after allograft posterior lumbar interbody fusion with pedicle screw and plate fixation. Spine 1994;19:271-1279.
8. Brantigan JW, Cunningham BW, Warden K, McAfee PC, Steffee AD. Compression strength of donor bone for posterior lumbar interbody fusion. Spine 1993;18:1213-1221.
9. Weiner BK, Fraser RD. Spine update. Lumbar interbody cages. Spine 1998;23:634-640.
10. McAfee PC. Interbody fusion cages in reconstructive operations on the spine. J Bone Joint Surg Am 1999;81:859-880.
11. McAfee PC, Cunningham BW, Lee GA, Orbegoso CM, Haggerty CJ, Fedder IL, Griffith SL. Revision strategies for salvaging or improving failed cylindrical cages. Spine 1999;24:2147-2153.
12. Togawa D, Bauer TW. The histology of human retrieved intervertebral body fusion cages: Good bone graft incorporation and few particles. Trans ORS 2001;655.
13. Kanayama M, et al. In vitro biomechanical investigation of the stability and stress-shielding effect of lumbar interbody fusion devices. J Neurosurg 2000;93(2 Suppl):259-265.
14. Regan JJ, Aronoff RJ, Ohnmeiss DD, Sengupta DK. Laparoscopic approach to L4-L5 for interbody fusion using BAK cages: Experience in the first 58 cases. Spine 1999;24:2171-2174.
15. Tullberg T. Failure of a carbon fiber implant. A case report. Spine 1998;23:1804-1806.
16. Regan JJ, Yuan H, McAfee PC. Laparoscopic fusion of the lumbar spine: Minimally invasive spine surgery. A prospective multicenter study evaluating open and laparoscopic lumbar fusion. Spine 1999;24:402-411.
17. Cunningham BW, Haggerty CJ, and McAfee PC. A quantitative densitometric study investigating the stress-shielding effects of interbody spinal fusion devicesEmphasis on long-term fusions in thoroughbred racehorses. Presented at the Annual Meeting of the Orthopaedic Research Society, New Orleans, LA, 1998.
18. Smit TH, van Dijk M, Arnoe MF, Wuisman PI. Mechanics of absorbable spinal cages perforating the endplates; an in vitro study. Trans ORS 2000;349.
19. van Dijk M, Smit TH, Sugihara S, Burger EH, Wuisman PIJM. The effect of cage stiffness on the rate of lumbar interbody fusion. An in vivo model using poly(L-lactic acid) and titanium cages. Spine 2002;27(7):682-688.
20. van der Elst M, Patka P, van der Werken C. Biodegradable implants in fracture fixation: state of the art. Unfallchirurg 2000;103:178-82.
21. Amecke B, Bendix D, Entenmann G. Resorbable polyesters: Composition, properties, applications. Clin Mater 1992;10:47-50.
22. Edwards, RC. The fate of resorbable poly-L-lactic/polyglycolic acid (LactoSorb) bone fixation devices in orthognathic surgery. J Oral Maxillofac Surg 2001;59:19-25.
23. Cordewener FW. The future of biodegradable osteosyntheses. Tissue Eng 2000;6:413-424.
24. Haers PE, Suuronen R, Lindqvist C, Sailer H. Biodegradable polylactide plates and screws in orthognathic surgery: Technical note [see comments]. J Craniomaxillofac Surg 1998;26:87-91.
25. Peltoniemi HH, Hallikainen D, Toivonen T, Helevirta P, Waris T. SR-PLLA and SR-PGA miniscrews: Biodegradation and tissue reactions in the calvarium and dura mater. J Craniomaxillofac Surg 1999;27:42-50.
26. Rokkanen PU. Bioabsorbable fixation in orthopaedic surgery and traumatology. Biomaterials 2000;21:2607-2613.
27. Tunc DC. In vivo degradation and biocompatability study of in vitro pre-degraded as-polymerized polylactide particles. Biomaterials 1996;17:2109-2112.
28. Bergsma JE, de Bruijn WC, Rozema FR, Bos RR, Boering G. Late degradation tissue response to poly(L-lactide) bone plates and screws. Biomaterials 1995;16:25-31.
29. Matsusue Y, Hanafusa S, Yamamuro T, Shikinami Y, Ikada Y. Tissue reaction of bioabsorbable ultra high strength poly (L-lactide) rod. A long-term study in rabbits. Clin Orthop 1995; 317:246-253.
30. Pihlajamaki H, Bostman O, Hirvensalo E, Tormala P, Rokkanen P. Absorbable pins of self-reinforced poly-L-lactic acid for fixation of fractures and osteotomies. J Bone Joint Surg Br 1992;74:853-857.
31. Brantigan JW et al. Interbody lumbar fusion using a carbon fiber cage implant versus allograft bone. An investigational study in the Spanish goat. Spine 1994;19(13):1436-1444.
32. Sandhu HS et al. Distractive properties of a threaded interbody fusion device. An in vivo model. Spine 1996;21(10):1201-1210.
33. Cunningham BW et al. Osteogenic protein versus autologous interbody arthrodesis in the sheep thoracic spine. A comparative endoscopic study using the Bagby and Kuslich interbody fusion device. Spine 1999;24(6):509-518.
34. Smit TH. The use of a quadruped as an in vivo model for the study of the spine - Biomechanical considerations. Eur Spine J 2002;11(2):137-144.
35. Ledet EH, Sachs BL, Brunski JB, Gatto CE, Donzelli PS. Real-time in vivo loading in the lumbar spine: Part 1. Interbody implant: Load cell design and preliminary results. Spine 2000; 25:2595-2600.
36. Evans JH. Biomechanics of lumbar fusion. Clin Orthop 1985; 193:38-46.
37. Steffen T, Marchesi D, Aebi M. Posterolateral and anterior interbody spinal fusion models in the sheep. Clin Orthop 2000; 371:28-37.
38. Ali SA, Doherty PJ, Williams DF. Mechanisms of polymer degradation in implantable devices. 2. Poly(DL-lactic acid). J Biomed Mater Res 1993;27:1409-1418.
39. Williams DF. Mechanisms of biodegradation of implantable polymers. Clin Mater 1992;10:9-12.
40. Mainil-Varlet P, Curtis R, Gogolewski S. Effect of in vivo and in vitro degradation on molecular and mechanical properties of various low-molecular-weight polylactides. J Biomed Mater Res 1997;36:360-380.
41. Pistner H, Bendix DR, Muhling J, Reuther JF. Poly(L-lactide): A long-term degradation study in vivo. Part III. Analytical characterization. Biomaterials 1993;14:291-298.
42. Chegini N, Hay DL, von Fraunhofer JA, Masterson BJ. A comparative scanning electron microscopic study on degradation of absorbable ligating clips in vivo and in vitro. J Biomed Mater Res 1988;22:71-79.
43. Matsusue Y, Yamamuro T, Oka M, Shikinami Y, Hyon SH, Ikada Y. In vitro and in vivo studies on bioabsorbable ultra high-strength poly(L-lactide) rods. J Biomed Mater Res 1992; 26:1553-1567.
44. Quereshy FA, Goldstein JA, Goldberg JS, Beg Z. The efficacy of bioresorbable fixation in the repair of mandibular fractures: An animal study. J Oral Maxillofac Surg 2000;58:1263-1269.
45. Jukkala-Partio K, Partio EK, Helevirta P, Pohjonen T, Törmälä P, Rokkanen P. Treatment of subcapital femoral neck fractures with bioabsorbable or metallic screw fixation. A preliminary report. Ann Chir Gynaecol 2000;89:45-52.