Polypharmacy and Inappropriate Medication Use in Singapore Nursing Homes

Annals of the Academy of Medicine Singapore

Volumn 33, Issue 1, 2004, Pages 49-52

  Mamun, K ^a   Lien, C T C ^a   Goh Tan, C Y E ^b   Ang, W S T ^a  

^a CHANGI GENERAL HOSPITAL   (Singapore)

^b SINGAPORE GENERAL HOSPITAL   (Singapore)

Author keywords

Elderly; Long term care; Quality indicator

Indexed keywords

ANTACID AGENT; ANTIDEPRESSANT AGENT; ANTIHISTAMINIC AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; CODEINE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; HISTAMINE H2 RECEPTOR ANTAGONIST; IRON; LAXATIVE; NEUROLEPTIC AGENT; NONSTEROID ANTIINFLAMMATORY AGENT; PARACETAMOL; SEDATIVE AGENT; SEROTONIN UPTAKE INHIBITOR; VITAMIN;

ANAMNESIS; ARTICLE; CONFIDENCE INTERVAL; DEMOGRAPHY; DRUG CONTRAINDICATION; DRUG DOSE REGIMEN; DRUG INDICATION; DRUG MISUSE; DRUG OVERDOSE; DRUG SAFETY; DRUG USE; HUMAN; MEDICAL PRACTICE; NURSING HOME; POLYPHARMACY; RANDOMIZATION; SINGAPORE;

EID: 1842812555     PISSN: 03044602     EISSN: 29724066     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. th ed. USA: Blackwell, 2002:37.
2. Population Planning Unit, Ministry of Health (Series V-February 1997) (for 2000-2030). Singapore: Ministry of Health, 1997.
3. National Center for Health Statistics: Health statistics on older persons - United States, 1986. DHHS Publication No. (PHS) 87-1409, June 1987. Washington, DC: DHHS Publication, 1987.
4. Jones D, Poole C. Medicine taking by elderly people: An overview. In: George CF, Woodhouse KW, Denham MJ, MacLennan WJ. editors. Drug Therapy in Old Age. Chichester, UK: Wiley and Sons, 1998:1-22.
5. Ostrom JR, Hammarlund ER, Christensen DB, Plein JB, Kethley AJ. Medication usage in an elderly population. Med Care 1985;23:157-64.
6. Chrischilles EA, Foley DJ, Wallace RB, Lemke JH, Semla TP, Hanlon JT, et al. Use of medications by persons 65 and over: data from the established populations for epidemiological studies of the elderly. J Gerontol 1992;47:M137-M144.
7. Beers MH, Ouslander JG, Fingold SF, Morgenstern H, Reuben DB, Rogers W, et al. Inappropriate medication prescribing in skilled-nursing facilities. Ann Intern Med 1992;117:684-9.
8. Bernabei R, Gambassi G, Lapane K, Sgadari A, Landi F, Gatsonis C, et al. Characteristics of SAGE database: a new resource for research on outcomes in long-term care. J Gerontol A Biol Sci Med Sci 1999;54:M25-M33.
9. Beers M, Avorn J, Soumerai S, Everitt OE, Sherman DS, Salem S. Psychoactive medication use in intermediate-care facility residents. JAMA 1988;260:3016-24.
10. Ray WA, Federspiel CF, Schaffner W. A study of antipsychotic drug use in nursing homes: epidemiological evidence suggesting misuse. Am J Public Health 1980;70:485-91.
11. Nolan L, O'Malley K. The need for a more rational approach to drug prescribing for elderly people in nursing homes. Age Ageing 1989;18:52-66.
12. Lindley CM, Tully MP, Paramsothy V, Tallis RC. Inappropriate medication is a major cause of adverse drug reaction in elderly patients. Age Ageing 1992;21:294-300.
13. Gray LS, Sager M, Lestico MR, Jalaluddin M. Adverse drug events in hospitalized elderly. J Gerontol A Biol Sci Med Sci 1998;53:M59-M63.
14. Hanlon JT, Schmader KE, Koronkowski MJ, Weinberger M, Landsman PB, Samsa GP, et al. Adverse drug reactions in high risk older outpatients. J Am Geriatr Soc 1997;45:945-8.
15. th ed. USA: Blackwell, 2002:40.
16. Lazarou J Pomernaz BH, Corey PN. Incidence of adverse drug reaction in hospitalized patients: a meta-analysis of prospective studies. JAMA 1998;279:1200-5.
17. th ed. USA: Blackwell, 2002:41.
18. Beers MH, Ouslander JG, Rollingher I, Brooks J, Reuben D, Beck JC. Explicit criteria for determining inappropriate medication use in nursing homes. Arch Intern Med 1991;151:1825-32.
19. Nolan L, O'Malley K. Prescribing for the elderly: Part 1. Sensitivity of the elderly to adverse drug reactions. J Am Geriatr Soc 1988;36:142-9.
20. Lamy PP. Adverse drug effects. Clin Geriatr Med 1990;6:293-307.
21. Omnibus Budget Regulation Act (OBRA) of 1987. PL100-203, December 22, 1987.
22. nd ed. USA: McGraw-Hill, 1997:372.
23. Beers MH. Explicit criteria for determining potentially inappropriate medication use by the elderly. Arch Intern Med 1997;157:1531-6.
24. Strand LM, Cipolle R, Morley PC. Drug-related problems: their structure and function. Drug Intell Clin Pharm 1990;24:1093-7.
25. th ed. USA: Lexi-comp Publications, 2001.
26. Leipzig RM, Cumming RG, Tinetti ME. Drugs and falls in older people: a systemic review and meta-analysis: II. Cardiac and analgesic drugs. J Am Geriatr Soc 1999;47:40-50.
27. Ray WA, Griffin MR, Schaffner W, Baugh DK, Melton LJ. Psychotropic drug use and the risk of hip fracture. N Engl J Med 1987;316:363-9.
28. Cumming RG, Klineberg RJ. Psychotropics, thiazide diuretics and hip fractures in the elderly. Med J Aust 1993;158:414-7.
29. Avorn J, Soumerai SB, Everitt DE, Ross-Degnan D, Beers MH, Sherman D, et al. A randomized trial of a program to reduce the use of psychoactive drugs in nursing homes. N Engl J Med 1992;327: 168-73.
30. Ray WA, Taylor JA, Meador KG, Lichtenstein MJ, Griffin MR, Fought R, et al. Reducing antipsychotic drug use in nursing homes. A controlled trial of provider education. Arch Intern Med 1993;153:713-21.
31. Gurwitz JH, Rochon P. Improving the quality of medication use in elderly patients: a not-so-simple prescription. Arch Intern Med 2002;162:1670-2.
32. Sloane PD, Zimmerman S, Brown LC, Ives TJ, Walsh JF. Inappropriate medication prescribing in residential care/assisted living facilities. J Am Geriatr Soc 2002;50:1001-11.
33. Gurwitz JH, Soumerai SB, Avorn J. Improving medication prescribing and utilization in the nursing home. J Am Geriatr Soc 1990;38:542-52.