A sensitive and restricted enzyme-linked immunosorbent assay for detecting a heterogeneous antibody population in serum from people suffering from a new variant of endemic pemphigus

Archives of Dermatological Research

Volumn 295, Issue 10, 2004, Pages 434-441

  Abréu Vélez, Ana María ^a   Yepes, Maria Mercedes ^b   Patiño, Pablo Javier ^b   Bollag, Wendy B ^a   Montoya Sr , Fernando ^b  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

^b UNIVERSIDAD DE ANTIOQUIA   (Colombia)

Author keywords

Autoimmunity; ELISA; Pemphigus

Indexed keywords

ANTIGEN; AUTOANTIBODY; CONCANAVALIN A; DESMOGLEIN 1; DESMOGLEIN 1 ANTIBODY; EPITOPE; IMMUNOGLOBULIN G4; MONOCLONAL ANTIBODY; PLECTIN; UNCLASSIFIED DRUG;

ADULT; ANTIBODY DETECTION; ANTIBODY RESPONSE; ARTICLE; CATTLE; COLOMBIA; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; DIAGNOSTIC ACCURACY; DISEASE ACTIVITY; ENDEMIC DISEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; EPIDEMIOLOGICAL DATA; ERYTHEMATOUS PEMPHIGUS; HUMAN; IMMUNOBLOTTING; IMMUNOFLUORESCENCE TEST; INTERMETHOD COMPARISON; MAJOR CLINICAL STUDY; MAXIMUM ALLOWABLE CONCENTRATION; PEMPHIGUS FOLIACEUS; PEMPHIGUS VULGARIS; PRIORITY JOURNAL; REFERENCE VALUE; SENSITIVITY AND SPECIFICITY; SKIN;

ANIMALS; AUTOANTIBODIES; AUTOANTIGENS; CADHERINS; CATTLE; COST-BENEFIT ANALYSIS; DESMOGLEIN 1; ENDEMIC DISEASES; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITOPES; FLUORESCENT ANTIBODY TECHNIQUE, DIRECT; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HUMANS; PEMPHIGUS; PEPTIDE FRAGMENTS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SKIN; TISSUE EXTRACTS;

EID: 1842781097     PISSN: 03403696     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00403-003-0441-4     Document Type: Article

References (42)

1. Castro RM, Proenca NG (1983) Semelhancas e diferencas entre o fogo selvagem e o penfigo foliaceo de Cazanave (Similarities and differences between South American pemphigus foliaceus and Cazanave's pemphigus foliaceus). An Bras Dermatol 53:137-139
2. Morini JP, Jomaa B, Gorgi Y, Saguem MH, Nouira R, Roujeau JC, Revuz J (1993) An endemic pemphigus foliaceus focus in the Sousse area of Tunisia. Arch Dermatol 129:69-73
3. Koulu L, Kusumi A, Steinberg MS, Klaus-kovtun V, Stanley JR (1984) Human autoantibodies against a desmosomal core protein in pemphigus foliaceus. J Exp Med 160:1509-1518
4. Kazerounian S, Mahoney MG, Uitto J, Aho S (2000) Envoplakin and periplakin, the paraneoplastic pemphigus antigens, are also recognized by pemphigus foliaceus autoantibodies. J Invest Dermatol 115:505-507
5. Nguyen VT, Ndoye A, Shultz LD, Pittelkow MR, Grando SA (2000) Antibodies against keratinocyte antigens other than desmogleins 1 and 3 can induce pemphigus vulgaris-like lesions. J Clin Invest 106:1467-1479
6. Diaz LA, Sampaio SAP, Rivitti EA, Macca LL, Roscoer JT, Takashashi Y, Labib RS, Patel HT, Mutassim DF, Dugan AM, Anhalt GJ (1987) An autoantibody in pemphigus serum, restriction for the 59 kDa keratin, selectively binds the surface of the keratinocytes: evidence for an extracellular keratin domain. J Invest Dermatol 89:287-295
7. Dugan EM, Labib RS, Anhalt GJ, Diaz LA (1989) Selective surface radioiodination of keratinocytes in primary culture labels a 59 kD keratin and other surface proteins. Arch Dermatol Res 281:463-469
8. Liu Z, Diaz LA, Haas AL, Giudice GJ (1992) cDNA cloning of a novel human ubiquitin carrier protein. An antigenic domain restrictionally recognized by endemic pemphigus foliaceus autoantibodies is encoded in a secondary reading frame of this human epidermal transcript. J Biol Chem 267:15829-15835
9. Dmochowski M, Hashimoto T, Garrod DR, Nishikawa T (1993) Desmocollins I and II are recognized by certain sera from patients with various types of pemphigus, particularly Brazilian pemphigus foliaceus. J Invest Dermatol 100:380-384
10. Kim SC, Kwon YD, Lee IJ, Chang SN, Lee TG (1997) cDNA cloning of the 210-kDa paraneoplastic pemphigus antigen reveals that envoplakin is a component of the antigen complex. J Invest Dermatol 109:365-369
11. Vu TN, Lee TX, Ndoye A, Shultz LD, Pittelkow MR, Dahl MV, Lynch PJ, Grando SA (1998) The pathophysiological significance of non-desmoglein targets of pemphigus autoimmunity. Development of antibodies against keratinocyte cholinergic receptors in patients with pemphigus vulgaris and pemphigus foliaceus. Arch Dermatol 134:971-980
12. Joly P, Gilbert D, Thomine E, Zitouni M, Ghohestani R, Delpech A, Lauret P, Tron F (1997) Identification of a new antibody population directed against a desmosomal plaque antigen in pemphigus vulgaris and pemphigus foliaceus. J Invest Dermatol 108:469-475
13. Amagai M, Komai A, Hashimoto T, Shirakata Y, Hashimoto K, Yamada T, Kitajima Y, Ohya K, Iwanami H, Nishikawa T (1999) Usefulness of enzyme-linked immunosorbent assay using recombinant desmogleins 1 and 3 for serodiagnosis of pemphigus. Br J Dermatol 140:351-357
14. Ishii K, Amagai M, Hall RP, Hashimoto T, Takayanagi A, Gamou S, Shimizu N, Nishikawa T (1997) Characterization of autoantibodies in pemphigus using antigen-restriction enzyme-linked immunoadsorbent assays with baculovirus-expressed recombinant desmogleins. J Immunol 159:2010-2017
15. Lenz P, Amagai M, Volc-Platzer B, Stingl G, Kirnbauer R (1999) Desmoglein 3-ELISA: a pemphigus vulgaris-restriction diagnostic tool. Arch Dermatol 135:143-148
16. Sami N, Bhol KC, Ahmed AR (2001) Diagnostic features of pemphigus vulgaris in patients with pemphigus foliaceus: detection of both autoantibodies, long-term follow-up and treatment responses. Clin Exp Immunol 125:492-498
17. Harman KE, Gration MJ, Seed PT, Bhogal BS, Challacombe SJ, Black MM (2000) Diagnosis of pemphigus by ELISA: a critical evaluation of two ELISAs for the detection of antibodies to the major pemphigus antigens, desmoglein 1 and 3. Clin Exp Dermatol 25:236-240
18. Bystryn JC, Akman A, Jiao D (2002) Limitations in enzyme-linked immunosorbent assays for antibodies against desmogleins 1 and 3 in patients with pemphigus. Arch Dermatol 138:1252-1253
19. Kljuic A, Bazzi H, Sundberg JP, Martinez-Mir A, O'Shaughnessy R, Mahoney MG, Levy M, Montagutelli X, Ahmad W, Aita VM, Gordon D, Uitto J, Whiting D, Ott J, Fischer S, Gilliam TC, Jahoda CA, Morris RJ, Panteleyev AA, Nguyen VT, Christiano AM (2003) Desmoglein 4 in hair follicle differentiation and epidermal adhesion. Evidence from inherited hypotrichosis and acquired pemphigus vulgaris. Cell 113:249-260
20. Abreu-Velez AM, Maldonado JG, Jaramillo A, Patiño PJ, Prada S, Leon W, Montoya F (1998) Immunological characterization of a unique focus of endemic pemphigus foliaceus in the rural area of El Bagre, Colombia. J Invest Dermatol 110: 516a
21. Abreu-Velez AM, Hashimoto T, Bollag WB, Tobon Arroyave S, Abreu-Velez CE, Londono ML, Montoya F, Beutner EH (2003) A unique form of endemic pemphigus in northern Colombia. J Am Acad of Dermatol 49:599-608
22. Abreu AM, Olague-Marchan M, Lopez-Swiderski A, Mascaro JM, Giudice GJ, Diaz LA (1997) Characterization of a 45 kD epidermal tryptic peptide recognized by pemphigus foliaceus sera. J Invest Dermatol 108:541a
23. Abreu-Velez AM, Beutner EH, Montoya F, Bollag WB, Hashimoto T (2003) Analyses of autoantigens in a new form of endemic pemphigus foliaceus in Colombia. J Am Acad of Dermatol 49:609-614
24. Labib RS, Rock B, Robledo MA, Anhalt GJ (1991) The calcium-sensitive epitope of pemphigus foliaceus antigen is present on a murine tryptic fragment and constitutes a major antigenic region for human autoantibodies. J Invest Dermatol 96:144-147
25. Diaz LA, Sampaio SAP, Rivitti EA, Martins CR, Cunha PR, Lombardi C, Almeida FA, Castro RM, Macca ML, Lavarado C (1989) Endemic pemphigus foliaceus (fogo selvagem). Clinical features and immunopathology. J Am Acad Dermatol 20:657-669
26. Viera JP (1942) Penfigo foliaceo e syndrome de Senear-Usher (Pemphigus foliaceus and Senear-Usher Syndrome). Empresa Grafica da Revista dos Tribunas, Sao Paulo
27. Kransy SA, Beutner EH, Chorzelski TP (1978) Restrictionity and sensitivity of indirect and direct immunofluorescent findings in the diagnosis of pemphigus. In: Beutner EH, Chorzelsi TP, Kumar V (eds) Immunopathology of the skin, 32nd edn. Wiley, New York, pp 207-247
28. Curtis PA, Dabney RJ (1977) Burns. Including gold chemicals and electrical injuries. In: Sabiston DC Jr (ed) Textbook of surgery. Saunders, Philadelphia, pp 297-298
29. Zillikens D, Mascaro JM Jr, Rose PA, Liu Z, Erwing SM, Caux F, Hoffmann RG, Diaz LA, Giudice G (1997) A highly sensitive enzyme-linked immunosorbent assay for the detection of circulating anti-BP180 autoantibodies associated with bullous pemphigoid. J Invest Dermatol 109:679-683
30. Labib RS, Rock B, Martins CR, Diaz LA (1990) Pemphigus foliaceus antigen: characterization of an immunoreactive tryptic fragment from BALB/c mouse epidermis recognized by all patient sera and major autoantibody subclasses. Clin Immunol Immunopathol 57:317-329
31. McCullough KC, Bruckner L, Schaffner R, Fraefel W, Muller HK, Kihm U (1992) Relationship between the anti-FMD virus antibody reaction as measured by different assays, and protection in vivo against challenge infection. Vet Microbiol 30:99-112
32. Imamura S, Takigawa M, Ofuji S (1979) Binding restrictionity of rabbit anti-guinea pig epidermal cell sera: comparison of their receptors with those of concanavalin A and pemphigus sera. Acta Derm Venereol 59:113-119
33. Crowther JR (1995) ELISA theory and practice. In: Crowther JR (ed) Methods in molecular biology. Humana Press, Totowa, NJ
34. Dow BC, Munro H, Ferguson K, Buchanan I, Jarvis L, Jordan T, Franklin IM, McClelland M (2001) HTLV antibody screening using mini-pools. Transfus Med 11:419-422
35. Quak JJ, Balm AJ, van Dongen GA, Brakkee JG, Scheper RJ, Snow GB, Meijer CJ (1990) A 22-kd surface antigen detected by monoclonal antibody E 48 is exclusively expressed in stratified squamous and transitional epithelia. Am J Pathol 136:191-197
36. Cheng SW, Amagai M, Nishikawa T (2002) Monitoring disease activity in pemphigus with enzyme-linked immunosorbent assay using recombinant desmogleins 1 and 3. Br J Dermatol 147:261-265
37. Hisamatsu Y, Abreu-Velez AM, Amagai M, Ogawa MM, Kanzaki T, Hashimoto T (2003) Comparative study of autoantigen profile between Colombian and Brazilian types of endemic pemphigus by various biochemical and molecular techniques. J Dermatol Sci 32:33-41
38. Silva dos Reis VM, Cucé LC, Rivitti EA (1991) Anatomopatologia e immunofluorescencia direta e indireta das lesoes de pênfigo foliáceo endêmico resistentes á corticoretapia (Histopathological, direct and indirect immunofluorescence studies of skin biopsies from people affected by endemic pemphigus foliaceus resistant to corticotherapy). Rev Inst Med Trop Sao Paulo 33:97-103
39. Martins-Castro R, Chorzelsi TD, Jablonska S, Marquart F (1976) Antiepithelial antibodies in healthy people living in the endemic areas of South American pemphigus foliaceus. Castellania 4:111-112
40. Kricheli D, David M, Frusik-Zotlink M, Goldsmith D, Rabinov M, Sulkes J, Milner Y (1999) The distribution of pemphigus vulgaris IgG subclasses and their reactivity to desmoglein 1 and 3 in pemphigus patients and their relatives. J Invest Dermatol 112:614a
41. Zhu XJ, Bystryn JC (1983) Heterogenicity of pemphigoid antigens. J Invest Dermatol 80:16-20
42. Rock B, Martins C, Diaz LA (1989) The pathogenic effect of IgG4 autoantibodies in endemic pemphigus foliaceus (Fogo selvagem). New Engl J Med 320:1464-1469