-
1
-
-
0034518116
-
Toxicogenomics-based discrimination of toxic mechanism in HepG2 human hepatoma cells
-
Burczynski M.E., McMillian M., Ciervo J., Li L., Parker J.B., Dunn R.T., Hicken S., Farr S., Johnson M.D. Toxicogenomics-based discrimination of toxic mechanism in HepG2 human hepatoma cells. Toxicol. Sci. 58:2000;399-415.
-
(2000)
Toxicol. Sci.
, vol.58
, pp. 399-415
-
-
Burczynski, M.E.1
McMillian, M.2
Ciervo, J.3
Li, L.4
Parker, J.B.5
Dunn, R.T.6
Hicken, S.7
Farr, S.8
Johnson, M.D.9
-
2
-
-
0034671424
-
Morphologic analysis correlates with gene expression changes in cultured F344 rat mesothelial cells
-
Crosby L.M., Hyder K.S., DeAngelo A.B., Kepler T.B., Gaskill B., Benavides G.R., Yoon L., Morgan K.T. Morphologic analysis correlates with gene expression changes in cultured F344 rat mesothelial cells. Toxicol. Appl. Pharmacol. 169:2000;205-221.
-
(2000)
Toxicol. Appl. Pharmacol.
, vol.169
, pp. 205-221
-
-
Crosby, L.M.1
Hyder, K.S.2
Deangelo, A.B.3
Kepler, T.B.4
Gaskill, B.5
Benavides, G.R.6
Yoon, L.7
Morgan, K.T.8
-
3
-
-
0032808416
-
Gene expression applied to toxicology
-
Farr S., Dunn R.T. Gene expression applied to toxicology. Toxicol. Sci. 50:1999;1-9.
-
(1999)
Toxicol. Sci.
, vol.50
, pp. 1-9
-
-
Farr, S.1
Dunn, R.T.2
-
4
-
-
0035092715
-
Challenges and limitations of gene expression profiling in mechanistic and predictive toxicology
-
Fielden M.R., Zacharewski T.R. Challenges and limitations of gene expression profiling in mechanistic and predictive toxicology. Toxicol. Sci. 60:2001;6-10.
-
(2001)
Toxicol. Sci.
, vol.60
, pp. 6-10
-
-
Fielden, M.R.1
Zacharewski, T.R.2
-
5
-
-
0030952485
-
Expression of growth factor receptors and their mRNAs in livers of mice and rats following administration of non-genotoxic carcinogens
-
Garcia-Allan C., Loughlin J., Orton T.C., Lord P.G. Expression of growth factor receptors and their mRNAs in livers of mice and rats following administration of non-genotoxic carcinogens. Arch. Toxicol. 71:1997;409-415.
-
(1997)
Arch. Toxicol.
, vol.71
, pp. 409-415
-
-
Garcia-Allan, C.1
Loughlin, J.2
Orton, T.C.3
Lord, P.G.4
-
6
-
-
0142128826
-
Gene expression analysis reveals chemical-specific profiles
-
Hamadeh H.K., Bushel P.R., Jayadev S., Martin K., DiSorbo O., Sieber S., Bennett L., Tennant R., Stoll R., Barrett J.C., Blanchard K., Paules R.S., Afshari C.A. Gene expression analysis reveals chemical-specific profiles. Toxicol. Sci. 67:2002;219-231.
-
(2002)
Toxicol. Sci.
, vol.67
, pp. 219-231
-
-
Hamadeh, H.K.1
Bushel, P.R.2
Jayadev, S.3
Martin, K.4
Disorbo, O.5
Sieber, S.6
Bennett, L.7
Tennant, R.8
Stoll, R.9
Barrett, J.C.10
Blanchard, K.11
Paules, R.S.12
Afshari, C.A.13
-
7
-
-
0034825987
-
The use of genomics technology to investigate gene expression changes in cultured human liver cells
-
Harries H.M., Fletcher S.T., Duggan C.M., Baker V.A. The use of genomics technology to investigate gene expression changes in cultured human liver cells. Toxicol. In Vitro. 15:2001;399-405.
-
(2001)
Toxicol. in Vitro
, vol.15
, pp. 399-405
-
-
Harries, H.M.1
Fletcher, S.T.2
Duggan, C.M.3
Baker, V.A.4
-
9
-
-
0037380651
-
Pharmacogenetics and pharmacogenomics in drug development and regulatory decision making: Report of the first FDA-PWG-PhRMA-DruSafe Workshop [Journal Article]
-
Lesko L.J., Salerno R.A., Spear B.B., Anderson D.C., Anderson T., Brazell C., Collins J., Dorner A., Essayan D., Gomez-Mancilla B., Hackett J., Huang S.M., Ide S., Killinger J., Leighton J., Mansfield E., Meyer R., Ryan S.G., Schmith V., Shaw P., Sistare F., Watson M., Worobec A. Pharmacogenetics and pharmacogenomics in drug development and regulatory decision making: report of the first FDA-PWG-PhRMA-DruSafe Workshop [Journal Article]. J. Clin. Pharmacol. 43:2003;342-358.
-
(2003)
J. Clin. Pharmacol.
, vol.43
, pp. 342-358
-
-
Lesko, L.J.1
Salerno, R.A.2
Spear, B.B.3
Anderson, D.C.4
Anderson, T.5
Brazell, C.6
Collins, J.7
Dorner, A.8
Essayan, D.9
Gomez-Mancilla, B.10
Hackett, J.11
Huang, S.M.12
Ide, S.13
Killinger, J.14
Leighton, J.15
Mansfield, E.16
Meyer, R.17
Ryan, S.G.18
Schmith, V.19
Shaw, P.20
Sistare, F.21
Watson, M.22
Worobec, A.23
more..
-
10
-
-
0035152959
-
CDNA microarrays in investigative toxicology: A study of differential gene expression in compound induced cardiac hypertrophy
-
Lord P.G., Barne K.A., Kramer K., Bacon E.J., Mooney J., O'Brien S., Bugelski P.J. cDNA microarrays in investigative toxicology: a study of differential gene expression in compound induced cardiac hypertrophy. Comments Toxicol. 7:2001;381-392.
-
(2001)
Comments Toxicol.
, vol.7
, pp. 381-392
-
-
Lord, P.G.1
Barne, K.A.2
Kramer, K.3
Bacon, E.J.4
Mooney, J.5
O'Brien, S.6
Bugelski, P.J.7
-
11
-
-
77957187478
-
New molecular endpoints and methods for routine toxicity testing
-
Macgregor J.T., Farr S., Tucker J.D., Heddle J.A., Tice R.R., Turteltaub K.W. New molecular endpoints and methods for routine toxicity testing. Fund. Appl. Toxicol. 26:1995;156-173.
-
(1995)
Fund. Appl. Toxicol.
, vol.26
, pp. 156-173
-
-
Macgregor, J.T.1
Farr, S.2
Tucker, J.D.3
Heddle, J.A.4
Tice, R.R.5
Turteltaub, K.W.6
-
12
-
-
0032901303
-
Microarrays and toxicology: The advent of toxicogenomics
-
Nuwaysir E.F., Bittner M., Trent J., Barrett J.C., Afshari C.A. Microarrays and toxicology: the advent of toxicogenomics. Mol. Carcinogenesis. 24:1999;153-159.
-
(1999)
Mol. Carcinogenesis.
, vol.24
, pp. 153-159
-
-
Nuwaysir, E.F.1
Bittner, M.2
Trent, J.3
Barrett, J.C.4
Afshari, C.A.5
-
13
-
-
0029941161
-
Expression of growth factors and growth factor receptors in the liver of C57BL/10J mice following administration of phenobarbitone
-
Orton T.C., Doughty S.E., Kalinowski A.E., Lord P.G., Wadsworth P.F. Expression of growth factors and growth factor receptors in the liver of C57BL/10J mice following administration of phenobarbitone. Carcinogenesis. 15:1996;973-981.
-
(1996)
Carcinogenesis
, vol.15
, pp. 973-981
-
-
Orton, T.C.1
Doughty, S.E.2
Kalinowski, A.E.3
Lord, P.G.4
Wadsworth, P.F.5
-
14
-
-
0036900945
-
Medical applications of microarray technologies: A regulatory science perspective
-
Petricoin E.F., Hackett J.L., Lesko L.J., Puri R.K., Gutman S.I., Chumakov K., Woodcock J., Feigal D.W., Zoon K.C., Sistare F.D. Medical applications of microarray technologies: a regulatory science perspective. Nature Genet. Suppl. 32:2002;474-479.
-
(2002)
Nature Genet. Suppl.
, vol.32
, pp. 474-479
-
-
Petricoin, E.F.1
Hackett, J.L.2
Lesko, L.J.3
Puri, R.K.4
Gutman, S.I.5
Chumakov, K.6
Woodcock, J.7
Feigal, D.W.8
Zoon, K.C.9
Sistare, F.D.10
-
15
-
-
0032779706
-
Differential gene expression in drug metabolism and toxicology: Practicalities
-
Rockett J.C., Esdaile D.J., Gibson G.G. Differential gene expression in drug metabolism and toxicology: practicalities. Xenobiotica. 29:1999;655-691.
-
(1999)
Xenobiotica
, vol.29
, pp. 655-691
-
-
Rockett, J.C.1
Esdaile, D.J.2
Gibson, G.G.3
-
16
-
-
0028041828
-
Effect of some peroxisome proliferators on transforming growth factor-b1 gene expression and insulin-like growth factor II/mannose-6-phosphate receptor gene expression in rat liver
-
Rumsby P.C., Davies M.J., Price R.J., Lake B.G. Effect of some peroxisome proliferators on transforming growth factor-b1 gene expression and insulin-like growth factor II/mannose-6-phosphate receptor gene expression in rat liver. Carcinogenesis. 15:1994;419-421.
-
(1994)
Carcinogenesis
, vol.15
, pp. 419-421
-
-
Rumsby, P.C.1
Davies, M.J.2
Price, R.J.3
Lake, B.G.4
-
17
-
-
0035369987
-
Key challenges for toxicologists in the 21st century
-
Smith L.L. Key challenges for toxicologists in the 21st century. Trends Pharmacol. Sci. 22:2001;281-285.
-
(2001)
Trends Pharmacol. Sci.
, vol.22
, pp. 281-285
-
-
Smith, L.L.1
-
18
-
-
0035213686
-
Identification of toxicologically predictive gene sets using cDNA microarrays
-
Thomas R.S., Rank D.R., Penn S.G., Zastrow G.M., Hayes K.R., Pande K., Glover E., Silander T., Craven M.W., Reddy J.K., Jovanovich S.B., Bradfield C.A. Identification of toxicologically predictive gene sets using cDNA microarrays. Mol. Pharmacol. 60:2001;1189-1194.
-
(2001)
Mol. Pharmacol.
, vol.60
, pp. 1189-1194
-
-
Thomas, R.S.1
Rank, D.R.2
Penn, S.G.3
Zastrow, G.M.4
Hayes, K.R.5
Pande, K.6
Glover, E.7
Silander, T.8
Craven, M.W.9
Reddy, J.K.10
Jovanovich, S.B.11
Bradfield, C.A.12
-
19
-
-
0036043671
-
Toxicogenomics and drug discovery: Will new technologies help us produce better drugs?
-
Ulrich R., Friend S.H. Toxicogenomics and drug discovery: will new technologies help us produce better drugs? Nature Rev. Drug Discovery. 1:2002;84-88.
-
(2002)
Nature Rev. Drug Discovery
, vol.1
, pp. 84-88
-
-
Ulrich, R.1
Friend, S.H.2
-
20
-
-
0021697881
-
The molecular genetics of cellular oncogenes
-
Varmus H.E. The molecular genetics of cellular oncogenes. Annu. Rev. Genet. 18:1985;553-612.
-
(1985)
Annu. Rev. Genet.
, vol.18
, pp. 553-612
-
-
Varmus, H.E.1
-
21
-
-
0035977845
-
Microarray analysis of hepatotoxins in vitro reveals a correlation between gene expression profiles and mechanisms of toxicity
-
Waring J.F., Ciurlionis R., Jolly R.A., Heindel M., Ulrich R.G. Microarray analysis of hepatotoxins in vitro reveals a correlation between gene expression profiles and mechanisms of toxicity. Toxicol. Lett. 120:2001;359-368.
-
(2001)
Toxicol. Lett.
, vol.120
, pp. 359-368
-
-
Waring, J.F.1
Ciurlionis, R.2
Jolly, R.A.3
Heindel, M.4
Ulrich, R.G.5
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