A long and winding road

Critical Care Medicine

Volumn 32, Issue 4, 2004, Pages 1077-1079

  Wunderink, Richard G ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Antibiotic resistant microorganisms; Nonresponding pneumonia; Nosocomial infection

Indexed keywords

AMINOGLYCOSIDE ANTIBIOTIC AGENT; ANTIBIOTIC AGENT; BETA LACTAMASE INHIBITOR; LINEZOLID; PENICILLIN G; VANCOMYCIN;

ANTIBIOTIC THERAPY; DRUG RESPONSE; EDITORIAL; HOSPITAL INFECTION; HUMAN; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MORTALITY; OXYGEN TENSION; PNEUMONIA; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; TREATMENT FAILURE; VENTILATOR;

ANTI-BACTERIAL AGENTS; CROSS INFECTION; DIAGNOSIS, DIFFERENTIAL; DRUG RESISTANCE, MICROBIAL; HAEMOPHILUS INFECTIONS; HUMANS; INTENSIVE CARE UNITS; MICROBIAL SENSITIVITY TESTS; PNEUMONIA, BACTERIAL; PNEUMONIA, STAPHYLOCOCCAL; RESPIRATION, ARTIFICIAL; TREATMENT FAILURE;

EID: 1842738311     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.CCM.0000119925.86432.44     Document Type: Editorial

References (14)

1. Ibrahim EH, Sherman G, Ward S, et al: The influence of inadequate antimicrobial treatment of bloodstream infections on patient outcomes in the ICU setting. Chest 2000; 118:146-155
2. Moise PA, Forrest A, Bhavnani SM, et al: Area under the inhibitory curve and a pneumonia scoring system for predicting outcomes of vancomycin therapy for respiratory infections by Staphylococcus aureus. Am J Health Syst Pharm 2000; 57(Suppl 2):S4-S9
3. Ibrahim EH, Ward S, Sherman G, et al: Experience with a clinical guideline for the treatment of ventilator-associated pneumonia. Crit Care Med 2001; 29:1109-1115
4. Fagon JY, Chastre J, Wolff M, et al: Invasive and noninvasive strategies for management of suspected ventilator-associated pneumonia: A randomized trial. Ann Intern Med 2000; 132:621-630
5. Brun-Buisson C, Sollet JP, Schweich H, et al: Treatment of ventilator-associated pneumonia with piperacillin-tazobactam/amikacin versus ceftazidime/amikacin: A multicenter, randomized controlled trial. VAP Study Group. Clin Infect Dis 1998; 26:346-354
6. Fagon J, Patrick H, Haas DW, et al: Treatment of Gram-positive nosocomial pneumonia: Prospective randomized comparison of quinupristin/dalfopristin versus vancomycin. Nosocomial Pneumonia Group. Am J Respir Crit Care Med 2000; 161:753-762
7. Wunderink RG, Rello J, Cammarata SK, et al: Linezolid vs vancomycin: Analysis of two double-blind studies of patients with methicillin-resistant Staphylococcus aureus nosocomial pneumonia. Chest 2003; 124:1789-1797
8. Ioanas M, Ferrer M, Cavalcanti M, et al: Causes and predictors of nonresponse to treatment of intensive care unit-acquired pneumonia. Crit Care Med 2004; 32:938-945
9. Luna CM, Blanzaco D, Niederman MS et al: Resolution of ventilator-associated pneumonia: Prospective evaluation of the clinical pulmonary infection score as an early clinical predictor of outcome. Crit Care Med 2003; 31:676-682
10. Dennesen PJ, Van der Ven AJ, Kessels AG, et al: Resolution of infectious parameters after antimicrobial therapy in patients with ventilator-associated pneumonia. Am J Respir Crit Care Med 2001; 163:1371-1375
11. Singh N, Rogers P, Atwood CW, et al: Short-course empiric antibiotic therapy for patients with pulmonary infiltrates in the intensive care unit: A proposed solution for indiscriminate antibiotic prescription. Am J Respir Crit Care Med 2000; 162:505-511
12. Fowler RA, Flavin KE, Barr J, et al: Variability in antibiotic prescribing patterns and outcomes in patients with clinically suspected ventilator-associated pneumonia. Chest 2003; 123:835-844
13. Bernard GR, Vincent JL, Laterre PF, et al: Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med 2001; 344:699-709
14. Peters M, Petros A, Dixon G, et al: Acquired immunoparalysis in paediatric intensive care: Prospective observational study. BMJ 1999; 319:609-610