Reduction of Single-Neuron Firing Uncertainty by Cortical Ensembles during Motor Skill Learning

Journal of Neuroscience

Volumn 24, Issue 14, 2004, Pages 3574-3582

  Cohen, Dana ^a   Nicolelis, Miguel A L ^a,b,c  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b Duke University   (United States)

^c DUKE UNIVERSITY   (United States)

Author keywords

Chronic recording; Extracellular; Motion; Motor activity; Motor cortex; Movement; Neural variability; Skill learning

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BEHAVIOR; ELECTRODE; EXTRACELLULAR RECORDING; LEARNING; MOTION; MOTOR ACTIVITY; MOTOR CORTEX; MOTOR PERFORMANCE; MOVEMENT (PHYSIOLOGY); NONHUMAN; PRIORITY JOURNAL; PROCEDURES CONCERNING CELLS; RAT; RESPONSE TIME; SPIKE; STEREOTYPY; STOCHASTIC MODEL;

ACOUSTIC STIMULATION; ACTION POTENTIALS; ALGORITHMS; ANIMALS; CHOICE BEHAVIOR; CONDITIONING (PSYCHOLOGY); ELECTRODES, IMPLANTED; LEARNING; MODELS, NEUROLOGICAL; MOTOR CORTEX; MOTOR SKILLS; MOVEMENT; NEURONS; PREDICTIVE VALUE OF TESTS; RATS; REACTION TIME; STOCHASTIC PROCESSES;

EID: 1842732210     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5361-03.2004     Document Type: Article

References (33)

1. Averbeck BB, Lee D (2003) Neural noise and movement-related codes in the macaque supplementary motor area. J Neurosci 23:7630-7641.
2. Bonato C, Zanette G, Fiaschi A, Rossini PM (2002) Activity-dependent modulation of synaptic transmission in the intact human motor cortex revealed with transcranial magnetic stimulation. Cereb Cortex 12:1057-1062.
3. Dayan P, Abbott L (2001) Theoretical neuroscience: computational and mathematical modeling of neural systems. Cambridge, MA: MIT.
4. Dosher BA, Lu ZL (1998) Perceptual learning reflects external noise filtering and internal noise reduction through channel reweighting. Proc Natl Acad Sci USA 95:13988-13993.
5. Dubnov S, El-Yaniv R, Gdalyahu Y, Schneidman E, Tishby N, Yona G (2002) A new nonparametric clustering algorithm based on iterative estimation of distance profiles. Machine Learn 47:35-61.
6. Gandolfo F, Li C, Benda BJ, Schioppa CP, Bizzi E (2000) Cortical correlates of learning in monkeys adapting to a new dynamical environment. Proc Natl Acad Sci USA 97:2259-2263.
7. Georgopoulos AP, Schwartz AB, Kettner RE (1986) Neuronal population coding of movement direction. Science 233:1416-1419.
8. Germain L, Lamarre Y (1993) Neuronal activity in the motor and premotor cortices before and after learning the associations between auditory stimuli and motor responses. Brain Res 611:175-179.
9. Gold J, Bennett PJ, Sekuler AB (1999) Signal but not noise changes with perceptual learning. Nature 402:176-178.
10. Kleim JA, Barbay S, Nudo RJ (1998) Functional reorganization of the rat motor cortex following motor skill learning. J Neurophysiol 80:3321-3325.
11. Kleim JA, Barbay S, Cooper NR, Hogg TM, Reidel CN, Remple MS, Nudo RJ (2002) Motor learning-dependent synaptogenesis is localized to functionally reorganized motor cortex. Neurobiol Learn Mem 77:63-77.
12. Laubach M, Wessberg J, Nicolelis MA (2000) Cortical ensemble activity increasingly predicts behaviour outcomes during learning of a motor task. Nature 405:567-571.
13. Lee D, Port NL, Kruse W, Georgopoulos AP (1998) Variability and correlated noise in the discharge of neurons in motor and parietal areas of the primate cortex. J Neurosci 18:1161-1170.
14. Li CS, Padoa-Schioppa C, Bizzi E (2001) Neuronal correlates of motor performance and motor learning in the primary motor cortex of monkeys adapting to an external force field. Neuron 30:593-607.
15. Lotze M, Braun C, Birbaumer N, Anders S, Cohen LG (2003) Motor learning elicited by voluntary drive. Brain 126:866-872.
16. Mitz AR, Godschalk M, Wise SP (1991) Learning-dependent neuronal activity in the premotor cortex: activity during the acquisition of conditional motor associations. J Neurosci 11:1855-1872.
17. Muellbacher W, Ziemann U, Boroojerdi B, Cohen L, Hallett M (2001) Role of the human motor cortex in rapid motor learning. Exp Brain Res 136:431-438.
18. Muellbacher W, Ziemann U, Wissel J, Dang N, Kofler M, Facchini S, Boroojerdi B, Poewe W, Hallett M (2002) Early consolidation in human primary motor cortex. Nature 415:640-644.
19. Nicolelis MA, Ghazanfar AA, Faggin BM, Votaw S, Oliveira LM (1997) Reconstructing the engram: simultaneous, multisite, many single neuron recordings. Neuron 18:529-537.
20. Nicolelis MA, Dimitrov D, Carmena JM, Crist R, Lehew G, Kralik JD, Wise SP (2003) Chronic, multisite, multielectrode recordings in macaque monkeys. Proc Natl Acad Sci USA 100:11041-11046.
21. Pauluis Q, Baker SN (2000) An accurate measure of the instantaneous discharge probability, with application to unitary joint-even analysis. Neural Comput 12:647-669.
22. Paz R, Boraud T, Natan C, Bergman H, Vaadia E (2003) Preparatory activity in motor cortex reflects learning of local visuomotor skills. Nat Neurosci 6:882-890.
23. Poggio T, Fahle M, Edelman S (1992) Fast perceptual learning in visual hyperacuity. Science 256:1018-1021.
24. Reina GA, Moran DW, Schwartz AB (2001) On the relationship between joint angular velocity and motor cortical discharge during reaching. J Neurophysiol 85:2576-2589.
25. Remple MS, Bruneau RM, VandenBerg PM, Goertzen C, Kleim JA (2001) Sensitivity of cortical movement representations to motor experience: evidence that skill learning but not strength training induces cortical reorganization. Behav Brain Res 123:133-141.
26. Rioult-Pedotti MS, Friedman D, Donoghue JP (2000) Learning-induced LTP in neocortex. Science 290:533-536.
27. Shadlen MN, Newsome WT (1998) The variable discharge of cortical neurons: implications for connectivity, computation, and information coding. J Neurosci 18:3870-3896.
28. Shadmehr R, Holcomb HH (1997) Neural correlates of motor memory consolidation. Science 277:821-825.
29. Todorov E, Jordan MI (2002) Optimal feedback control as a theory of motor coordination. Nat Neurosci 5:1226-1235.
30. Ungerleider LG, Doyon J, Karni A (2002) Imaging brain plasticity during motor skill learning. Neurobiol Learn Mem 78:553-564.
31. van Vreeswijk C, Sompolinsky H (1996) Chaos in neuronal networks with balanced excitatory and inhibitory activity. Science 274:1724-1726.
32. Wise SP, Moody SL, Blomstrom KJ, Mitz AR (1998) Changes in motor cortical activity during visuomotor adaptation. Exp Brain Res 121:285-299.
33. Wolpert DM, Ghahramani Z, Flanagan JR (2001) Perspectives and problems in motor learning. Trends Cogn Sci 5:487-494.