Severe amitriptyline overdose with hypocalcemia;Schwere amitriptylinvergiftung mit hypocalcämie

Intensivmedizin und Notfallmedizin

Volumn 41, Issue 2, 2004, Pages 99-104

  Hermanns Clausen, M ^a   Rauch, F ^b  

^a Vergiftungs Informations Zentrale   (Germany)

^b Hospital of Rheinfelden   (Germany)

Author keywords

Amitriptyline overdose; Cyclic antidepressants; Hypocalcemia

Indexed keywords

AMITRIPTYLINE; CALCIUM; MIDAZOLAM; POTASSIUM CHANNEL; TRICYCLIC ANTIDEPRESSANT AGENT;

ADULT; ARTICLE; ARTIFICIAL VENTILATION; ASPIRATION PNEUMONIA; CALCIUM BLOOD LEVEL; CASE REPORT; COMA; DEPRESSION; DISEASE ASSOCIATION; DISEASE SEVERITY; DRUG BLOOD LEVEL; DRUG EFFECT; DRUG OVERDOSE; ELECTROCARDIOGRAM; ENDOTRACHEAL INTUBATION; FEMALE; FOCAL EPILEPSY; HUMAN; HYPOCALCEMIA; HYPOTHERMIA; QRS COMPLEX; QT INTERVAL; QT PROLONGATION; SUICIDE ATTEMPT; TABLET;

EID: 1842714450     PISSN: 01753851     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00390-004-0436-1     Document Type: Article

References (11)

1. Amerson AB, Wanke LA, Editorial Staff (2003) Amitriptyline - Drug Evaluation (Most recent revision 12/2002). In: Hutchison TA, Shahan DR (eds) DRUGDEX® System. MICROMEDEX, Greenwood Village, Colorado
2. Burkhardt KK, Hurlbut KM, Vicas I, Kulig K, Howland MA (2003) Antidepressants, tricyclic (Most recent revision 05/02). In: Toll LL, Hurlbut KM (eds) POISINDEX® System. MICROMEDEX, Greenwood Village, Colorado
3. Jo SH, Youm JB, Lee CO, Earm YE, Ho WK (2000) Blockade of the HERG human cardiac K(+) channel by the antidepressant drug amitriptyline. Br J Pharmacol 129:1474-1480
4. Pentel PR, Benowitz NL (1997) Cyclic antidepressants: 624-650. In: Ellenhorn, MJ Schonwald Snordog G Wasserberger J (eds) Ellenhorn's Medical Toxicology: Diagnosis and Treatment of Human Poisoning. Williams and Wilkins, Baltimore Philadelphia London Paris
5. Pentel PR, Keyler DE (2001) Cyclic Antidepressants. In: Ford MD, Delaney KA, Ling LJ, Erickson T (eds) Clinical Toxicology. WB Saunders Company, Philadelphia London New York St. Louis Sydney Toronto, pp 522-531
6. Schulz A, Schmoldt M (1997) Therapeutic and toxic blood concentration of more than 500 drugs. Pharmazie 52:895-911
7. Schwabe U, Paffrath D (2003) Arzneiverordnungsreport 2002. Springer, Berlin
8. Seger DL, Hantsch C, Zavoral T, Wrenn K (2003) Variability of Recommendations for Serum Alkalinization in Tricyclic Antidepressant Overdose: A Survey of US Poison Center Medical Directors. J Toxicol Clin Toxicol 41:331-338
9. Shah R, Uren Z, Baker A, Majeed A (2001) Deaths from antidepressants in England and Wales 1993-1997: analysis of a new national database. Psychol Med 31:1203-1210
10. Thomas L (2003) Albumin. In: Thomas L (Hrsg) Labor und Diagnose. TH-Books Verlagsgesellschaft mbH, Frankfurt/Main
11. Vale JA (1997) Position Statement: Gastric Lavage. American Academy of Clinical Toxicology; European Association of Poisons Centres and Clinical Toxicologists. J Toxicol Clin Toxicol 35:711-719