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Volumn 5, Issue 2, 1998, Pages 136-143

New findings and treatment strategies for hypoglycemia and hypoglycemia unawareness

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDIABETIC AGENT; INSULIN;

EID: 0031776183     PISSN: 10683097     EISSN: None     Source Type: Journal    
DOI: 10.1097/00060793-199804000-00009     Document Type: Review
Times cited : (4)

References (73)
  • 1
    • 0003010451 scopus 로고    scopus 로고
    • Hypoglycemia in insulin-dependent diabetes mellitus: Interplay of insulin excess and compromised glucose counter-regulation
    • Edited by Porte D Jr, Sherwin RS. Stamford: Appleton & Lange
    • Cryer PE, Gerich JE: Hypoglycemia in insulin-dependent diabetes mellitus: interplay of insulin excess and compromised glucose counter-regulation. In Diabetes Mellitus, edn 5. Edited by Porte D Jr, Sherwin RS. Stamford: Appleton & Lange; 1997:745-760.
    • (1997) Diabetes Mellitus, Edn 5. , pp. 745-760
    • Cryer, P.E.1    Gerich, J.E.2
  • 2
    • 0030913976 scopus 로고    scopus 로고
    • Hierarchy of physiological responses to hypoglycemia: Relevance to clinical hypoglycemia in type 1 (insulin dependent) diabetes mellitus
    • Cryer PE: Hierarchy of physiological responses to hypoglycemia: relevance to clinical hypoglycemia in type 1 (insulin dependent) diabetes mellitus. Horm Metab Res 1997, 29:92-96. Excellent review of hypoglycemia in diabetes.
    • (1997) Horm Metab Res , vol.29 , pp. 92-96
    • Cryer, P.E.1
  • 3
    • 0027370108 scopus 로고
    • The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus
    • The Diabetes Control and Complications Trial Research Group: The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med 1993, 329:977-986.
    • (1993) N Engl J Med , vol.329 , pp. 977-986
  • 4
    • 0031006603 scopus 로고    scopus 로고
    • Hypoglycemia in the Diabetes Control and Complications Trial: The Diabetes Control and Complications Trial Research Group
    • The Diabetes Control and Complications Trial Research Group: Hypoglycemia in the Diabetes Control and Complications Trial: the Diabetes Control and Complications Trial Research Group. Diabetes 1997, 46:271-286. The most detailed analysis of hypoglycemia in the largest study of diabetes control and complications.
    • (1997) Diabetes , vol.46 , pp. 271-286
  • 5
    • 0027275397 scopus 로고
    • The effect of long-term intensified insulin treatment on the development of microvascular complications of diabetes mellitus
    • Reichard P, Nilsson BY, Rosenqvist U: The effect of long-term intensified insulin treatment on the development of microvascular complications of diabetes mellitus. N Engl J Med 1993, 329:304-309.
    • (1993) N Engl J Med , vol.329 , pp. 304-309
    • Reichard, P.1    Nilsson, B.Y.2    Rosenqvist, U.3
  • 6
    • 0027952951 scopus 로고
    • Mortality and treatment side-effects during long-term intensified conventional insulin treatment in the Stockholm Diabetes Intervention Study
    • Reichard P, Pihl M: Mortality and treatment side-effects during long-term intensified conventional insulin treatment in the Stockholm Diabetes Intervention Study. Diabetes 1994, 43:313-317.
    • (1994) Diabetes , vol.43 , pp. 313-317
    • Reichard, P.1    Pihl, M.2
  • 7
    • 1842404206 scopus 로고    scopus 로고
    • Brain abnormalities demonstrated by magnetic resonance imaging in adult IDDM patients with and without a history of recurrent severe hypoglycemia
    • Perros P, Deary IJ, Sellar RJ, Best JJ, Frier BM: Brain abnormalities demonstrated by magnetic resonance imaging in adult IDDM patients with and without a history of recurrent severe hypoglycemia. Diabetes Care 1997, 20:1013-1018.
    • (1997) Diabetes Care , vol.20 , pp. 1013-1018
    • Perros, P.1    Deary, I.J.2    Sellar, R.J.3    Best, J.J.4    Frier, B.M.5
  • 8
    • 0029162104 scopus 로고
    • Hypoglycemia-induced cognitive dysfunction in diabetes mellitus: Effect of hypoglycemia unawareness
    • Gold AE, MacLeod KM, Deary IJ, Frier BM: Hypoglycemia-induced cognitive dysfunction in diabetes mellitus: effect of hypoglycemia unawareness. Physiol Behav 1995, 58:501-511.
    • (1995) Physiol Behav , vol.58 , pp. 501-511
    • Gold, A.E.1    MacLeod, K.M.2    Deary, I.J.3    Frier, B.M.4
  • 10
    • 0030035394 scopus 로고    scopus 로고
    • Quantitative EEG in type 1 diabetic children with and without episodes of severe hypoglycemia: A controlled, blind study
    • Bjorgaas M, Sand T, Grimse R: Quantitative EEG in type 1 diabetic children with and without episodes of severe hypoglycemia: a controlled, blind study. Acta Neurol Scand 1996, 93:398-402.
    • (1996) Acta Neurol Scand , vol.93 , pp. 398-402
    • Bjorgaas, M.1    Sand, T.2    Grimse, R.3
  • 13
    • 0029147687 scopus 로고
    • Intensive insulin therapy prevents the progression of diabetic microvascular complications in Japanese patients with non-insulin-dependent diabetes mellitus: A randomized prospective 6-year study
    • Ohkubo Y, Kishikawa H, Araki E, Miyata T, Isammi S, Motoyoshi S, Kojima Y, Furuyoshi N, Shichiri M: Intensive insulin therapy prevents the progression of diabetic microvascular complications in Japanese patients with non-insulin-dependent diabetes mellitus: a randomized prospective 6-year study. Diabetes Res Clin Pract 1995, 28:103-117.
    • (1995) Diabetes Res Clin Pract , vol.28 , pp. 103-117
    • Ohkubo, Y.1    Kishikawa, H.2    Araki, E.3    Miyata, T.4    Isammi, S.5    Motoyoshi, S.6    Kojima, Y.7    Furuyoshi, N.8    Shichiri, M.9
  • 14
    • 0031024007 scopus 로고    scopus 로고
    • Altered hierarchy of protective responses against severe hypoglycemia in normal aging in healthy men
    • Matyka K, Evans M, Lomas J, Cranston I, Macdonald I, Amiel SA: Altered hierarchy of protective responses against severe hypoglycemia in normal aging in healthy men. Diabetes Care 1997, 20:135-141.
    • (1997) Diabetes Care , vol.20 , pp. 135-141
    • Matyka, K.1    Evans, M.2    Lomas, J.3    Cranston, I.4    Macdonald, I.5    Amiel, S.A.6
  • 15
    • 0030758711 scopus 로고    scopus 로고
    • Rates of hypoglycemic in users of sulfonylureas
    • Van Staa T, Abenhaim L, Monette J: Rates of hypoglycemic in users of sulfonylureas. J Clin Epidemiol 1997, 50:735-741.
    • (1997) J Clin Epidemiol , vol.50 , pp. 735-741
    • Van Staa, T.1    Abenhaim, L.2    Monette, J.3
  • 16
    • 0030852089 scopus 로고    scopus 로고
    • Incidence and risk factors for serious hypoglycemic in older persons using insulin or sulfonylureas
    • Shorr RI, Ray WA, Daugherty JR, Griffin MR: Incidence and risk factors for serious hypoglycemic in older persons using insulin or sulfonylureas. Arch Intern Med 1997, 157:1681-1686.
    • (1997) Arch Intern Med , vol.157 , pp. 1681-1686
    • Shorr, R.I.1    Ray, W.A.2    Daugherty, J.R.3    Griffin, M.R.4
  • 17
    • 0031157125 scopus 로고    scopus 로고
    • Clinical review: Hypoglycemia unawareness in noninsulin-dependent diabetes mellitus
    • Veneman TF, Erkelens DW: Clinical review: hypoglycemia unawareness in noninsulin-dependent diabetes mellitus. J Clin Endocrinol Metab 1997, 82:1682-1684.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 1682-1684
    • Veneman, T.F.1    Erkelens, D.W.2
  • 18
    • 0021263283 scopus 로고
    • Defective glucose counterregulation after subcutaneous insulin in noninsulin-dependent diabetes mellitus: Paradoxical suppression of glucose utilization and lack of compensatory increase in glucose production, roles of insulin resistance, abnormal neuroendocrine responses, and islet paracrine interactions
    • Bolli GB, Tsalikian E, Haymond MW, Cryer PE, Gerich JE: Defective glucose counterregulation after subcutaneous insulin in noninsulin-dependent diabetes mellitus: paradoxical suppression of glucose utilization and lack of compensatory increase in glucose production, roles of insulin resistance, abnormal neuroendocrine responses, and islet paracrine interactions. J Clin Invest 1984, 73:1532-1541.
    • (1984) J Clin Invest , vol.73 , pp. 1532-1541
    • Bolli, G.B.1    Tsalikian, E.2    Haymond, M.W.3    Cryer, P.E.4    Gerich, J.E.5
  • 19
    • 0028363238 scopus 로고
    • Increased epinephrine and skeletal muscle responses to hypoglycemia in non-insulin-dependent diabetes mellitus
    • Shamoon H, Friedman S, Canton C, Zacharowicz L, Hu M, Rossetti L: Increased epinephrine and skeletal muscle responses to hypoglycemia in non-insulin-dependent diabetes mellitus. J Clin Invest 1994, 93:2562-2571.
    • (1994) J Clin Invest , vol.93 , pp. 2562-2571
    • Shamoon, H.1    Friedman, S.2    Canton, C.3    Zacharowicz, L.4    Hu, M.5    Rossetti, L.6
  • 20
    • 0029972617 scopus 로고    scopus 로고
    • Evaluation of cardiac sympathetic nervous function by 123I-metaiodobenzylguanidine scintigraphy in insulin-treated non-insulin dependent diabetics with hypoglycemia unawareness
    • Ohno T, Toyama T, Hoshizaki H, Okamoto E, Naito S, Nogami A, Kamiyama H, Ohshima S, Yuasa K, Taniguchi K, et al.: Evaluation of cardiac sympathetic nervous function by 123I-metaiodobenzylguanidine scintigraphy in insulin-treated non-insulin dependent diabetics with hypoglycemia unawareness. Intern Med 1996, 35:94-99.
    • (1996) Intern Med , vol.35 , pp. 94-99
    • Ohno, T.1    Toyama, T.2    Hoshizaki, H.3    Okamoto, E.4    Naito, S.5    Nogami, A.6    Kamiyama, H.7    Ohshima, S.8    Yuasa, K.9    Taniguchi, K.10
  • 21
    • 0030799479 scopus 로고    scopus 로고
    • Prevention of an increase in plasma cortisol during hypoglycemia preserves subsequent counter-regulatory responses
    • Davis SN, Shavers C, Davis B, Costa F: Prevention of an increase in plasma cortisol during hypoglycemia preserves subsequent counter-regulatory responses. J Clin Invest 1997, 100:429-438.
    • (1997) J Clin Invest , vol.100 , pp. 429-438
    • Davis, S.N.1    Shavers, C.2    Davis, B.3    Costa, F.4
  • 22
    • 0029999961 scopus 로고    scopus 로고
    • Role of cortisol in the pathogenesis of deficient counterregulation after antecedent hypoglycemia in normal humans
    • Davis SN, Shavers C, Costa F, Mosqueda-Garcia R: Role of cortisol in the pathogenesis of deficient counterregulation after antecedent hypoglycemia in normal humans. J Clin Invest 1996, 98:680-691. Perhaps the most important new insight in the genesis of defective hypoglycemia counterregulation in recent years.
    • (1996) J Clin Invest , vol.98 , pp. 680-691
    • Davis, S.N.1    Shavers, C.2    Costa, F.3    Mosqueda-Garcia, R.4
  • 25
    • 0022870296 scopus 로고
    • Corticotropin-releasing factor receptor antagonist: Effects on the autonomic nervous system and cardiovascular function
    • Brown MR, Gray TS, Fisher LA: Corticotropin-releasing factor receptor antagonist: effects on the autonomic nervous system and cardiovascular function. Regul Pept 1986, 16:321-329.
    • (1986) Regul Pept , vol.16 , pp. 321-329
    • Brown, M.R.1    Gray, T.S.2    Fisher, L.A.3
  • 26
    • 0031895015 scopus 로고    scopus 로고
    • Effects of dexamethasone in vivo and in vitro on glucose transport in brain microvasculature
    • Chipkin SR, Van Bueren A, Bercel E, McCall AL: Effects of dexamethasone in vivo and in vitro on glucose transport in brain microvasculature. Neurochem Res 1998, 23:649-656.
    • (1998) Neurochem Res , vol.23 , pp. 649-656
    • Chipkin, S.R.1    Van Bueren, A.2    Bercel, E.3    McCall, A.L.4
  • 27
    • 0025132115 scopus 로고
    • Brain glucose utilization and transport and cortical function in chronic vs. acute hypoglycemia
    • Pelligrino DA, Segil LJ, Albrecht RF: Brain glucose utilization and transport and cortical function in chronic vs. acute hypoglycemia. Am J Physiol 1990, 259:E729-E735.
    • (1990) Am J Physiol , vol.259
    • Pelligrino, D.A.1    Segil, L.J.2    Albrecht, R.F.3
  • 29
    • 0029558465 scopus 로고
    • Brain glucose uptake and unawareness of hypoglycemia in patients with insulin-dependent diabetes mellitus
    • Boyle PJ, Kempers SF, O'Connor AM, Nagy RJ: Brain glucose uptake and unawareness of hypoglycemia in patients with insulin-dependent diabetes mellitus. N Engl J Med 1995, 333:1726-1731.
    • (1995) N Engl J Med , vol.333 , pp. 1726-1731
    • Boyle, P.J.1    Kempers, S.F.2    O'Connor, A.M.3    Nagy, R.J.4
  • 31
    • 0030583628 scopus 로고    scopus 로고
    • Differential gene regulation of CNS noradrenergic and dopaminergic neurons by diabetes
    • Figlewicz DP, Brot MD, McCall AL, Szot P: Differential gene regulation of CNS noradrenergic and dopaminergic neurons by diabetes. Brain Res 1996, 736:54-60.
    • (1996) Brain Res , vol.736 , pp. 54-60
    • Figlewicz, D.P.1    Brot, M.D.2    McCall, A.L.3    Szot, P.4
  • 32
    • 0027329082 scopus 로고
    • The effect of insulin on norepinephrine uptake by PC12 cells
    • Figlewicz DP, Bentson K, Ocrant I: The effect of insulin on norepinephrine uptake by PC12 cells. Brain Res Bull 1993, 32:425-431.
    • (1993) Brain Res Bull , vol.32 , pp. 425-431
    • Figlewicz, D.P.1    Bentson, K.2    Ocrant, I.3
  • 33
    • 0027400795 scopus 로고
    • Insulin reduces norepinephrine transporter mRNA in vivo in rat locus coeruleus
    • Figlewicz DP, Szot P, Israel PA, Payne C, Dorsa DM: Insulin reduces norepinephrine transporter mRNA in vivo in rat locus coeruleus. Brain Res 1993, 602:161-164.
    • (1993) Brain Res , vol.602 , pp. 161-164
    • Figlewicz, D.P.1    Szot, P.2    Israel, P.A.3    Payne, C.4    Dorsa, D.M.5
  • 34
    • 0030069591 scopus 로고    scopus 로고
    • Insulin transport from plasma into the central nervous system is inhibited by dexamethasone in dogs
    • Baura GD, Foster DM, Kaiyala K, Porte D Jr, Kahn SE, Schwartz MW: Insulin transport from plasma into the central nervous system is inhibited by dexamethasone in dogs. Diabetes 1996, 45:86-90.
    • (1996) Diabetes , vol.45 , pp. 86-90
    • Baura, G.D.1    Foster, D.M.2    Kaiyala, K.3    Porte Jr., D.4    Kahn, S.E.5    Schwartz, M.W.6
  • 35
    • 0029916579 scopus 로고    scopus 로고
    • Insulin-associated modulation of neuroendocrine counterregulation, hypoglycemia perception, and cerebral function in insulin-dependent diabetes mellitus: Evidence for an intrinsic effect of insulin on the central nervous system
    • Lingenfelser T, Overkamp D, Renn W, Buettner U, Kimmerle K, Schmalfuss A, Jakober B: Insulin-associated modulation of neuroendocrine counterregulation, hypoglycemia perception, and cerebral function in insulin-dependent diabetes mellitus: evidence for an intrinsic effect of insulin on the central nervous system. J Clin Endocrinol Metab 1996, 81:1197-1205.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 1197-1205
    • Lingenfelser, T.1    Overkamp, D.2    Renn, W.3    Buettner, U.4    Kimmerle, K.5    Schmalfuss, A.6    Jakober, B.7
  • 38
    • 2642593026 scopus 로고    scopus 로고
    • Autonomic mediation of glucagon secretion during hypoglycemia: Implications for impaired A-cell responses in type 1 diabetes
    • in press
    • Taborsky GJ Jr, Ahren B, Havel PJ: Autonomic mediation of glucagon secretion during hypoglycemia: implications for impaired A-cell responses in type 1 diabetes. Diabetes 1998, in press. An excellent review of the regulation of glucagon secretion and the role of the autonomic nervous system in hypoglycemia.
    • (1998) Diabetes
    • Taborsky Jr., G.J.1    Ahren, B.2    Havel, P.J.3
  • 39
    • 0030936890 scopus 로고    scopus 로고
    • Activation of autonomic nerves and the adrenal medulla contributes to increased glucagon secretion during moderate insulin-induced hypoglycemia in women
    • Havel PJ, Ahren B: Activation of autonomic nerves and the adrenal medulla contributes to increased glucagon secretion during moderate insulin-induced hypoglycemia in women. Diabetes 1997, 46:801-807.
    • (1997) Diabetes , vol.46 , pp. 801-807
    • Havel, P.J.1    Ahren, B.2
  • 40
    • 0029956210 scopus 로고    scopus 로고
    • Autonomic mediation of glucagon secretion during insulin-induced hypoglycemia in rhesus monkeys
    • Havel PJ, Valverde C: Autonomic mediation of glucagon secretion during insulin-induced hypoglycemia in rhesus monkeys. Diabetes 1996, 45:960-966.
    • (1996) Diabetes , vol.45 , pp. 960-966
    • Havel, P.J.1    Valverde, C.2
  • 41
    • 0030041974 scopus 로고    scopus 로고
    • Pancreatic sympathetic nerves contribute to increased glucagon secretion during severe hypoglycemia in dogs
    • Havel PJ, Mundinger TO, Taborsky GJ Jr: Pancreatic sympathetic nerves contribute to increased glucagon secretion during severe hypoglycemia in dogs. Am J Physiol 1996, 270:E20-E26.
    • (1996) Am J Physiol , vol.270
    • Havel, P.J.1    Mundinger, T.O.2    Taborsky Jr., G.J.3
  • 42
    • 0028337286 scopus 로고
    • Redundant parasympathetic and sympathoadrenal mediation of increased glucagon secretion during insulin-induced hypoglycemia in conscious rats
    • Havel PJ, Parry SJ, Stern JS, Akpan JO, Gingerich RL, Taborsky GJ Jr, Curry DL: Redundant parasympathetic and sympathoadrenal mediation of increased glucagon secretion during insulin-induced hypoglycemia in conscious rats. Metab Clin Exp 1994, 43:860-866.
    • (1994) Metab Clin Exp , vol.43 , pp. 860-866
    • Havel, P.J.1    Parry, S.J.2    Stern, J.S.3    Akpan, J.O.4    Gingerich, R.L.5    Taborsky Jr., G.J.6    Curry, D.L.7
  • 43
    • 0031036141 scopus 로고    scopus 로고
    • Defective glucagon secretion during sustained hypoglycemia following successful islet allo- and autotransplantation in humans
    • Kendall DM, Teuscher AU, Robertson RP: Defective glucagon secretion during sustained hypoglycemia following successful islet allo- and autotransplantation in humans. Diabetes 1997, 46:23-27.
    • (1997) Diabetes , vol.46 , pp. 23-27
    • Kendall, D.M.1    Teuscher, A.U.2    Robertson, R.P.3
  • 44
    • 0030904145 scopus 로고    scopus 로고
    • Pancreas transplantation restores epinephrine response and symptom recognition during hypoglycemia in patients with long-standing type I diabetes and autonomic neuropathy
    • Kendall DM, Rooney DP, Smets YFG, Salazar BL, Robertson RP: Pancreas transplantation restores epinephrine response and symptom recognition during hypoglycemia in patients with long-standing type I diabetes and autonomic neuropathy. Diabetes 1997, 46:249-257.
    • (1997) Diabetes , vol.46 , pp. 249-257
    • Kendall, D.M.1    Rooney, D.P.2    Smets, Y.F.G.3    Salazar, B.L.4    Robertson, R.P.5
  • 46
    • 0031038124 scopus 로고    scopus 로고
    • Local ventromedial hypothalamus glucose perfusion blocks counterregulation during systemic hypoglycemia in awake rats
    • Borg MA, Sherwin RS, Borg WP, Tamborlane WV, Shulman GI: Local ventromedial hypothalamus glucose perfusion blocks counterregulation during systemic hypoglycemia in awake rats. J Clin Invest 1997, 99:361-365. One of three papers from this group that nicely demonstrate the crucial role of the hypothalamus in counterregulatory hormone responses to hypoglycemia.
    • (1997) J Clin Invest , vol.99 , pp. 361-365
    • Borg, M.A.1    Sherwin, R.S.2    Borg, W.P.3    Tamborlane, W.V.4    Shulman, G.I.5
  • 47
    • 0028931891 scopus 로고
    • Local ventromedial hypothalamus glucopenia triggers counterregulatory hormone release
    • Borg WP, Sherwin RS, During MJ, Borg MA, Shulman GI: Local ventromedial hypothalamus glucopenia triggers counterregulatory hormone release. Diabetes 1995, 44:180-184.
    • (1995) Diabetes , vol.44 , pp. 180-184
    • Borg, W.P.1    Sherwin, R.S.2    During, M.J.3    Borg, M.A.4    Shulman, G.I.5
  • 48
    • 0028296222 scopus 로고
    • Ventromedial hypothalamic lesions in rats suppress counterregulatory responses to hypoglycemia
    • Borg WP, During MJ, Sherwin RS, Borg MA, Brines ML, Shulman GI: Ventromedial hypothalamic lesions in rats suppress counterregulatory responses to hypoglycemia. J Clin Invest 1994, 93:1677-1682.
    • (1994) J Clin Invest , vol.93 , pp. 1677-1682
    • Borg, W.P.1    During, M.J.2    Sherwin, R.S.3    Borg, M.A.4    Brines, M.L.5    Shulman, G.I.6
  • 49
    • 0028809505 scopus 로고
    • Upregulation of blood-brain barrier GLUT1 glucose transporter protein and mRNA in experimental chronic hypoglycemia
    • Kumagai AK, Kang YS, Boado RJ, Pardridge WM: Upregulation of blood-brain barrier GLUT1 glucose transporter protein and mRNA in experimental chronic hypoglycemia. Diabetes 1995, 44:1399-1404.
    • (1995) Diabetes , vol.44 , pp. 1399-1404
    • Kumagai, A.K.1    Kang, Y.S.2    Boado, R.J.3    Pardridge, W.M.4
  • 50
    • 0000814639 scopus 로고
    • Glucose transporter gene expression in rat brain: Pretranslational changes associated with chronic insulin-induced hypoglycemia, fasting, and diabetes
    • Koranyi L, Bourey RE, James D, Mueckler M, Fiedorek GT Jr, Permutt MA: Glucose transporter gene expression in rat brain: pretranslational changes associated with chronic insulin-induced hypoglycemia, fasting, and diabetes. Mol Cell Neurosc 1991, 2:244-252.
    • (1991) Mol Cell Neurosc , vol.2 , pp. 244-252
    • Koranyi, L.1    Bourey, R.E.2    James, D.3    Mueckler, M.4    Fiedorek Jr., G.T.5    Permutt, M.A.6
  • 51
    • 0030972576 scopus 로고    scopus 로고
    • Chronic insulin hypoglycemia induces GLUT-3 protein in rat brain neurons
    • Uehara Y, Nipper V, McCall AL: Chronic insulin hypoglycemia induces GLUT-3 protein in rat brain neurons. Am J Physiol 1997, 272:E716-E719. First demonstration that neurons specifically adapt their glucose transporters in response to hypoglycemia.
    • (1997) Am J Physiol , vol.272
    • Uehara, Y.1    Nipper, V.2    McCall, A.L.3
  • 53
    • 0030035377 scopus 로고    scopus 로고
    • The measurement of cognitive function during acute hypoglycaemia: Experimental limitations and their effect on the study of hypoglycaemia unawareness
    • Heller SR, Macdonald IA: The measurement of cognitive function during acute hypoglycaemia: experimental limitations and their effect on the study of hypoglycaemia unawareness. Diabet Med 1996, 13:607-615.
    • (1996) Diabet Med , vol.13 , pp. 607-615
    • Heller, S.R.1    Macdonald, I.A.2
  • 54
    • 0030741922 scopus 로고    scopus 로고
    • Preservation of physiological responses to hypoglycemia 2 days after antecedent hypoglycemia in patients with IDDM
    • George E, Marques JL, Harris ND, Macdonald IA, Hardisty CA, Heller SR: Preservation of physiological responses to hypoglycemia 2 days after antecedent hypoglycemia in patients with IDDM. Diabetes Care 1997, 20:1228-1230.
    • (1997) Diabetes Care , vol.20 , pp. 1228-1230
    • George, E.1    Marques, J.L.2    Harris, N.D.3    Macdonald, I.A.4    Hardisty, C.A.5    Heller, S.R.6
  • 55
    • 0029079768 scopus 로고
    • Prolonged but partial impairment of the hypoglycaemic physiological response following short-term hypoglycaemia in normal subjects
    • George E, Harris N, Bedford C, Macdonald IA, Hardisty CA, Heller SR: Prolonged but partial impairment of the hypoglycaemic physiological response following short-term hypoglycaemia in normal subjects. Diabetologia 1995, 38:1183-1190.
    • (1995) Diabetologia , vol.38 , pp. 1183-1190
    • George, E.1    Harris, N.2    Bedford, C.3    Macdonald, I.A.4    Hardisty, C.A.5    Heller, S.R.6
  • 56
    • 0031204959 scopus 로고    scopus 로고
    • IDDM, counterregulation, and the brain
    • McCall AL: IDDM, counterregulation, and the brain. Diabetes Care 1997, 20:1228-1230.
    • (1997) Diabetes Care , vol.20 , pp. 1228-1230
    • McCall, A.L.1
  • 57
    • 13344249781 scopus 로고    scopus 로고
    • Effect of caffeine on recognition of and physiological responses to hypoglycaemia in insulin-dependent diabetes
    • Debrah K, Sherwin RS, Murphy J, Kerr D: Effect of caffeine on recognition of and physiological responses to hypoglycaemia in insulin-dependent diabetes. Lancet 1996, 347:19-24.
    • (1996) Lancet , vol.347 , pp. 19-24
    • Debrah, K.1    Sherwin, R.S.2    Murphy, J.3    Kerr, D.4
  • 59
  • 60
    • 0027444659 scopus 로고
    • Meticulous prevention of hypoglycemia normalizes the glycemic thresholds and magnitude of most of neuroendocrine responses to, symptoms of, and cognitive function during hypoglycemia in intensively treated patients with short-term IDDM
    • Fanelli CG, Epifano L, Rambotti AM, Pampanelli S, Di Vincenzo A, Modarelli F, Lepore M, Annibale B, Ciofetta M, Bottini P, et al.: Meticulous prevention of hypoglycemia normalizes the glycemic thresholds and magnitude of most of neuroendocrine responses to, symptoms of, and cognitive function during hypoglycemia in intensively treated patients with short-term IDDM. Diabetes 1993, 42:1683-1689.
    • (1993) Diabetes , vol.42 , pp. 1683-1689
    • Fanelli, C.G.1    Epifano, L.2    Rambotti, A.M.3    Pampanelli, S.4    Di Vincenzo, A.5    Modarelli, F.6    Lepore, M.7    Annibale, B.8    Ciofetta, M.9    Bottini, P.10
  • 61
    • 0028608981 scopus 로고
    • Reversal of hypoglycemia unawareness, but not defective glucose counterregulation, in IDDM
    • Dagogo-Jack S, Rattarasarn C, Cryer PE: Reversal of hypoglycemia unawareness, but not defective glucose counterregulation, in IDDM. Diabetes 1994, 43:1426-1434.
    • (1994) Diabetes , vol.43 , pp. 1426-1434
    • Dagogo-Jack, S.1    Rattarasarn, C.2    Cryer, P.E.3
  • 62
    • 0028954779 scopus 로고
    • Improvement of impaired counterregulatory hormone response and symptom perception by short-term avoidance of hypoglycemia in IDDM
    • Lingenfelser T, Buettner U, Martin J, Tobis M, Renn W, Kaschel R, Jakober B: Improvement of impaired counterregulatory hormone response and symptom perception by short-term avoidance of hypoglycemia in IDDM. Diabetes Care 1995, 18:321-325.
    • (1995) Diabetes Care , vol.18 , pp. 321-325
    • Lingenfelser, T.1    Buettner, U.2    Martin, J.3    Tobis, M.4    Renn, W.5    Kaschel, R.6    Jakober, B.7
  • 64
    • 0030915548 scopus 로고    scopus 로고
    • Reduction of postprandial hyperglycemic and frequency of hypoglycemia in IDDM patients on insulin-analog treatment: Multicenter Insulin Lispro Study Group
    • Anderson JH Jr, Brunelle RL, Koivisto VA, Pfutzner A, Trautmann ME, Vignati L, Dimarchi R: Reduction of postprandial hyperglycemic and frequency of hypoglycemia in IDDM patients on insulin-analog treatment: Multicenter Insulin Lispro Study Group. Diabetes 1997, 46:265-270.
    • (1997) Diabetes , vol.46 , pp. 265-270
    • Anderson Jr., J.H.1    Brunelle, R.L.2    Koivisto, V.A.3    Pfutzner, A.4    Trautmann, M.E.5    Vignati, L.6    Dimarchi, R.7
  • 67
    • 0028864006 scopus 로고
    • Improved postprandial metabolic control after subcutaneous injection of a short-acting insulin analog in IDDM of short duration with residual pancreatic beta-cell function
    • Pampanelli S, Torlone E, Lalli C, Del Sindaco P, Ciofetta M, Lepre M, Bartocci L, Brunetti P, Bolli GB: Improved postprandial metabolic control after subcutaneous injection of a short-acting insulin analog in IDDM of short duration with residual pancreatic beta-cell function. Diabetes Care 1995, 18:1452-1459.
    • (1995) Diabetes Care , vol.18 , pp. 1452-1459
    • Pampanelli, S.1    Torlone, E.2    Lalli, C.3    Del Sindaco, P.4    Ciofetta, M.5    Lepre, M.6    Bartocci, L.7    Brunetti, P.8    Bolli, G.B.9
  • 68
    • 0028607457 scopus 로고
    • Banting Lecture. Hypoglycaemia: The limiting factor in the management of IDDM
    • Cryer PE: Banting Lecture. Hypoglycaemia: the limiting factor in the management of IDDM. Diabetes 1994, 43:1378-1389.
    • (1994) Diabetes , vol.43 , pp. 1378-1389
    • Cryer, P.E.1
  • 69
    • 0030799514 scopus 로고    scopus 로고
    • Further evidence for a high incidence of nocturnal hypoglycaemia in IDDM: No effect of dose for dose transfer between human and porcine insulins
    • George E, Bedford C, Peacey SR, Hardisty CA, Heller SR: Further evidence for a high incidence of nocturnal hypoglycaemia in IDDM: no effect of dose for dose transfer between human and porcine insulins. Diabet Med 1997, 14:442-448.
    • (1997) Diabet Med , vol.14 , pp. 442-448
    • George, E.1    Bedford, C.2    Peacey, S.R.3    Hardisty, C.A.4    Heller, S.R.5
  • 70
    • 0029883144 scopus 로고    scopus 로고
    • Use of uncooked cornstarch to avert nocturnal hypoglycemia in children and adolescents with type I diabetes
    • Kaufman FR, Devgan S: Use of uncooked cornstarch to avert nocturnal hypoglycemia in children and adolescents with type I diabetes. J Diabetes Complications 1996, 10:84-87.
    • (1996) J Diabetes Complications , vol.10 , pp. 84-87
    • Kaufman, F.R.1    Devgan, S.2
  • 71
    • 0030762452 scopus 로고    scopus 로고
    • Alanine and terbutaline in the prevention of nocturnal hypoglycemia in IDDM
    • Saleh TV, Cryer PE: Alanine and terbutaline in the prevention of nocturnal hypoglycemia in IDDM. Diabetes Care 1997, 20:1231-1236.
    • (1997) Diabetes Care , vol.20 , pp. 1231-1236
    • Saleh, T.V.1    Cryer, P.E.2
  • 72
    • 0031048013 scopus 로고    scopus 로고
    • Glycemic control and sliding scale insulin use in medical inpatients with diabetes mellitus
    • Queale WS, Seidler AJ, Brancati FL: Glycemic control and sliding scale insulin use in medical inpatients with diabetes mellitus. Arch Intern Med 1997, 157:545-552.
    • (1997) Arch Intern Med , vol.157 , pp. 545-552
    • Queale, W.S.1    Seidler, A.J.2    Brancati, F.L.3
  • 73
    • 0030837024 scopus 로고    scopus 로고
    • Effects of differing antecedent hypoglycemia on subsequent counterregulation in normal humans
    • Davis SN, Shavers C, Mosqueda-Garcia R, Costa F: Effects of differing antecedent hypoglycemia on subsequent counterregulation in normal humans. Diabetes 1997, 48:1328-1335.
    • (1997) Diabetes , vol.48 , pp. 1328-1335
    • Davis, S.N.1    Shavers, C.2    Mosqueda-Garcia, R.3    Costa, F.4


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