Less inhibition of interferon-γ to organism growth in host cells may contribute to the high susceptibility of C3H mice to Chlamydia trachomatis lung infection

Immunology

Volumn 111, Issue 4, 2004, Pages 453-461

  Qiu, Hongyu ^a   Yang, Jie ^a   Bai, Hong ^a   Fan, Yijun ^a   Wang, Shuhe ^a   Han, Xiaobing ^a   Chen, Lijun ^a   Yang, Xi ^a,b  

^a UNIVERSITY OF MANITOBA   (Canada)

^b UNIVERSITY OF MANITOBA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 4; NITRIC OXIDE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY RESPONSE; ARTICLE; BACTERIAL GROWTH; BACTERIAL VIRULENCE; CELL CULTURE; CELLULAR IMMUNITY; CHLAMYDIA TRACHOMATIS; CHLAMYDIASIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE SEVERITY; FEMALE; HOST SUSCEPTIBILITY; HYPERSENSITIVITY; IMMUNE RESPONSE; INFECTION SENSITIVITY; LUNG INFECTION; LYMPH NODE CELL; MACROPHAGE; MORTALITY; MOUSE; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; SPLEEN; SPLEEN CELL;

ANIMALS; ANTIBODIES, BACTERIAL; CELLS, CULTURED; CHLAMYDIA INFECTIONS; CHLAMYDIA TRACHOMATIS; CYTOKINES; DISEASE SUSCEPTIBILITY; FEMALE; HYPERSENSITIVITY, DELAYED; INTERFERON TYPE II; LUNG; MACROPHAGES; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; PNEUMONIA, BACTERIAL; SPECIES SPECIFICITY; SURVIVAL RATE; TH1 CELLS;

EID: 1842684208     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0019-2805.2004.01835.x     Document Type: Article

References (38)

1. Grayston JT, Wang S-P. New knowledge of chlamydia and the diseases they cause. J Infect Dis 1975; 132:87.
2. Schatcher J. Chlamydia infections. N Engl J Med 1978; 298:540.
3. Morrison PR, Manning DS, Caldwell HD. Immunology of Chlamydia trachomatis infections: immunoprotective and immunopathogenic responses. In: Quinn TC, ed. Sexually Transmitted Diseases. New York: Raven Press, 1992:57.
4. Ward ME. The immunobiology and immunopathology of chlamydial infections. APMIS 1995; 130:769.
5. Yang X, Brunham RC. Role of T-cell mediated immunity in host defence against Chlamydia trachomatis and its implication for vaccine development. Can J Infec Dis 1998; 9:99-108.
6. Rottenberg ME, Gigliotti-Rothfuchs A, Wigzell H. The role of IFN-γ in the outcome of chlamydial infection. Curr Opin Immunol 2002; 14:444-51.
7. Cain TK, Rank RG. Local Th1-like responses are induced by intravaginal infection of mice with the mouse pneumonitis biovar of Chlamydia trachomatis. Infect Immun 1995; 63:1784-9.
8. Landers DV, Erlich K, Sung M, Schatcher J. Role of L3T4-bearing T-cell populations in experimental chlamydial salpingitis. Infect Immun 1991; 59:3744.
9. Su H, Caldwell H. CD4 T cells play a significant role in adoptive immunity to Chlamydia trachomatis infection of the mouse genital tract. Infect Immun 1995; 63:3302.
10. Magee DM, Igietseme JU, Smith JG, Bleicker CA, Grubbs BG, Schachter J, Rank RG, Williams DM. Chlamydia trachomatis pneumonia in the severe combined immunodeficiency (SCID) mouse. Reg Immunol 1993; 5:305.
11. Yang X, HayGlass KT, Brunham RC. Genetically determined differences in IL-10 and IFN-γ responses correlate with clearance of Chlamydia trachomatis mouse pneumonitis infection. J Immunol 1996; 156:4338.
12. Yang X, Brunham RC. Gene knockout B cell-deficient mice demonstrate that B cells play an important role in the initiation of T cell responses to Chlamydia trachomatis (mouse pneumonitis) lung infection. J Immunol 1998; 161:1439.
13. Yang X, Brunham RC. Different roles are played by α/β and γ/δ T cells in acquired immunity to Chlamydia trachomatis mouse pneumonitis pulmonary infection. Immunol 1998; 94:469.
14. Yang X, Gartner J, Zhu L, Wang S, Brunham RC. IL-10 gene knockout mice show enhanced ThI like protective immunity and absent granuloma formation following Chlamydia trachomatis lung infection. J Immunol 1999; 162:1010.
15. Rottenberg ME, Rothfuchs AG, Gigliotti D, Ceausu M, Une C, Levitsky V, Wigzell H. Regulation and role of IFN-γ in the innate resistance to infection with chlamydia pneumoniae. J Immunol 2000; 164:4812.
16. Wang S, Fan Y, Brunham RC, Yang X. IFN-γ knockout mice show Th2-associated delayed-type hypersensitivity and the inflammatory cells fail to localize and control chlamydial infection. Eur J Immunol 1999; 29:3782.
17. Johansson M, Schon K, Ward M, Lycke N. Genital tract infection with Chlamydia trachomatis fails to induce protective immunity in γ interferon receptor-deficient mice despite a strong local immunoglobulin A response. Infect Immun 1997; 65:1032-44.
18. Lu H, Yang X, Takeda K et al. Chlamydia trachomatis mouse pneumonitis lung infection in IL-18 and IL-12 knockout mice: IL-12 is dominant over IL-18 for protective immunity. Mol Med 2000; 6:604-12.
19. Huang J, Wang MD, Lenz S, Gao D, Kaltenboeck B. IL-12 administered during Chlamydia psittaci lung infection in mice confers immediate and long-term protection and reduces macrophage inflammatory protein-2 level and neutrophil infiltration in lung tissue. J Immunol 1999; 162:2217.
20. Holland MJ, Balley RL, Hayes LJ, Whittle HC, Mabey DCW. Conjunctival scarring in trachoma is associated with depressed cell-mediated immune response to chlamydial antigen. J Infect Dis 1993; 168:1528.
21. Holland MJ, Bailey RL, Conway DJ, Culley F, Miranpuri B, Byrne GI, Whittle HC, Mabdy DC. T helper type-1 (Th1) /Th2 profiles of peripheral blood mononuclear cell (PBMC) responses to antigens of Chlamydia trachomatis in subjects with severe trahomatous scarring. Clin Exp Immunol 1996; 105:429.
22. Brunham RC, Peeling RW. Chlamydia trachomatis antigens: role in immunity and pathogenesis. Infect Agents Dis 1994; 3:218-33.
23. Darville T, Andrews CW, Laffoon KK, Shymasani W, Kishen LR, Rank RG. Mouse strain-dependent variation in the course and outcome of chlamydial genital tract infection is associated with differences in host response. Infect Immun 1997; 65:3065.
24. Rottenberg ME, Rothfuchs AG, Gigliotti D, Svanholm C, Bandholtz L, Wigzell H. Role of innate and adaptive immunity in the outcome of primary infection with chlamydia pneumoniae, as analyzed in genetically modified mice. J. Immunol 1999; 162:2829.
25. de la Maza LM, Pal S, Khamesipour A, Peterson EM. Intravaginal inoculation of mice with the Chlamydia trachomatis mouse pneumonitis biovar results in infertility. Infect Immun 1994; 62:2094-7.
26. Darville T, Andrews CW Jr, Sikes JD, Fraley PL, Rank RG. Early local cytokine profiles in strains of mice with different outcomes from chlamydial genital tract infection. Infect Immun 2001; 69:3556.
27. Darville T, Andrews CW Jr, Sikes JD, Fraley PL, Braswell L, Rank RG. Mouse strain-dependent chemokine regulation of the genital tract T helper cell type 1 immune response. Infect Immun 2001; 69:7419.
28. Lewis JM. Isolation of alveolar macrophages, peritoneal macrophages, and Kupffer cells. In: Burleson GR, Dean JH, Munson AE, eds. Methods in Immunotoxicology, Vol 2. New York: Wileyliss, 1995:15-26.
29. Salkowski CA, Barber SA, Detore GR, Vogel SN. Differential dysregulation of nitric oxide production in macrophages with targeted disruptions in IFN regulatory factor-1 and -2 genes. J Immunol 1996; 156:3107-10.
30. Igietseme JU. Molecular mechanism of T-cell control of chlamydia in mice: role of nitric oxide in vivo. Immunology 1996; 88:1-5.
31. Karupiah G, Xie QW, Buller RM, Nathan C, Duarte C, MacMicking JD. Inhibition of viral replication by interferon-γ-induced nitric oxide synthase. Science 1993; 261:1445-8.
32. Stenger S, Thuring H, Rollinghoff M, Bogdan C. Tissue expression of inducible nitric oxide synthase is closely associated with resistance to Leishmania major. J Exp Med 1994; 180:783-93.
33. Igietseme JU, Uriri IM, Hawkins R, Rank RG. Integrin-mediated epithelial-T cell interaction enhances nitric oxide production and increased intracellular inhibition of chlamydia. J Leukoc Biol 1996; 59:656-62.
34. Cobb JP, Danner RL. Nitric oxide and septic shock. JAMA 1996; 275:1192-6.
35. MacMicking J, Xie QW, Nathan C. Nitric oxide and macrophage function. Annu Rev Immunol 1997; 15:323-50.
36. Corbett JA, Mcdaniel ML. Does nitric oxide mediate autoimmune destruction of β-cells? Diabetes 1992; 41:897-903.
37. Huang J, Degraves FJ, Lenz SD, Gao D, Feng P, Li D, Schlapp T, Kaltenboeck B. The quantity of nitric oxide released by macrophages regulates chlamydia-induced disease. Proc Natl Acad Sci USA 2002; 99:3914-19.
38. Der SD, Zhou A, Williams BR, Silverman RH. Identification of genes differentially regulated by interferon α, β or γ using oligonucleotide arrays. Proc Natl Acad Sci USA 1998; 98:6680-5.