Indirect determination of the irinotecan metabolite 7-ethyl-10-O- glucuronyl-camptothecin in human samples

Analytical Biochemistry

Volumn 328, Issue 1, 2004, Pages 84-86

  De Bruijn, Peter ^a   Willems, Edwin W ^a   Loos, Walter J ^a   Verweij, Jaap ^a   Sparreboom, Alex ^a,b  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CHEMISTRY;

CAMPTOTHECIN (CPT); IRINOTECAN;

METABOLITES;

7 ETHYL 10 HYDROXYCAMPTOTHECIN; 7 ETHYL 10 HYDROXYCAMPTOTHECIN GLUCURONIDE; 7 ETHYL 10 O GLUCURONYLCAMPTOTHECIN; CAMPTOTHECIN DERIVATIVE; DRUG METABOLITE; IRINOTECAN; UNCLASSIFIED DRUG;

ACCURACY; ARTICLE; DRUG BLOOD LEVEL; HUMAN; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

EID: 1842635686     PISSN: 00032697     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ab.2004.01.007     Document Type: Article

References (7)

1. Vanhoefer U., Harstrick A., Achterrath W., Cao S., Seeber S., Rustum Y.M. J. Clin. Oncol. 19:2001;1501-1518.
2. Mathijssen R.H., van Alphen R.J., Verweij J., Loos W.J., Nooter K., Stoter G., Sparreboom A. Clin. Cancer Res. 7:2001;2182-2194.
3. Iyer L., Das S., Janisch L., Wen M., Ramirez J., Karrison T., Fleming G.F., Vokes E.E., Schilsky R.L., Ratain M.J. Pharmacogenomics J. 2:2002;43-47.
4. Rivory L.P., Robert J. Cancer Chemother. Pharmacol. 36:1995;176-179.
5. Byrd G.D., Caldwell W.S., Bhatti B.S., Ravard A., Crooks P.A. Drug Metabol. Drug Interact. 16:2000;281-297.
6. Bedford C.T. J. Chromatogr. B. 717:1998;313-326.
7. de Bruijn P., Verweij J., Loos W.J., Nooter K., Stoter G., Sparreboom A. J. Chromatogr. B Biomed. Sci. Appl. 698:1997;277-285.