Evidence of androgen receptor expression in lichen sclerosus: An immunohistochemical study

Journal of the Society for Gynecologic Investigation

Volumn 5, Issue 6, 1998, Pages 331-333

  Kohlberger, Petra D ^a   Joura, Elmar A ^b   Bancher, Dagmar ^b   Gitsch, Gerald ^b   Breitenecker, Gerhard ^b   Kieback, Dirk G ^b  

^a UNIVERSITY OF FREIBURG   (Germany)

^b NONE

Author keywords

Androgen receptor; Immunohistochemistry; Lichen sclerosus

Indexed keywords

ANDROGEN RECEPTOR; ESTROGEN RECEPTOR; PROGESTERONE RECEPTOR; TESTOSTERONE;

ADULT; AGED; ANDROGEN THERAPY; ARTICLE; CLINICAL ARTICLE; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LICHEN SCLEROSUS ET ATROPHICUS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PUNCH BIOPSY; TISSUE PREPARATION; TOPICAL DRUG ADMINISTRATION;

ADULT; AGED; AGED, 80 AND OVER; BIOPSY; CELL NUCLEUS; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; LICHEN SCLEROSUS ET ATROPHICUS; MIDDLE AGED; RECEPTORS, ANDROGEN; RECEPTORS, ESTROGEN; RECEPTORS, PROGESTERONE; SKIN; TESTOSTERONE; VULVAR DISEASES;

EID: 0032211399     PISSN: 10715576     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1071-5576(98)00033-1     Document Type: Article

References (15)

1. Paslin D. Treatment of lichen sclerosus with topical dihydrotestosterone. Obstet Gynecol. 78:1991;1046-1049.
2. Joura E.A., Zeisler H., Bancher-Todesca D., Sator M.O., Schneider B., Gitsch G. Short-term effects of topical testosterone in vulvar lichen sclerosus. Obstet Gynecol. 89:1997;297-299.
3. Sideri M., Origoni M., Spinaci L., Ferrari A. Topical testosterone in the treatment of vulvar lichen sclerosus. Int J Gynaecol Obstet. 46:1994;53-56.
4. Bracco G.L., Carli P., Sonni L., et al. Clinical and histologic effect of topical treatments of vulval lichen sclerosus a critical evaluation . Reprod Med. 38:1993;36-40.
5. Kehoe S., Luesley D. Pathology and management of vulval pain and pruritus. Curr Opin Obstet Gynecol. 7:1995;16-19.
6. Tremaine R.D., Miller R.A. Lichen sclerosus et atrophicus. Int J Dermatol. 28:1989;10-16.
7. Cantwell A.R. Histologic observations of pleomorphic variably acid-fast bacteria in scleroderma, morphea, and lichen sclerosus et atrophicus. Int J Dermatol. 23:1984;45-52.
8. Jeffcoate T.N. Chronic vulval dystrophies. Am J Obstet Gynecol. 95:1966;61-74.
9. Kaufman M., Straisfeld C., Pinsky L. Expression of androgen-responsive properties in human skin fibroblast strains of genital and nongenital origin. Somat Cell Mol Genet. 3:1977;17-25.
10. Carli P., Bracco G., Taddei G., et al. Vulvar lichen sclerosus immunohistologic evaluation before and after therapy . J Reprod Med. 39:1994;110-114.
11. Choudhry R., Hodgins M.B., Van der Kwast T.H., Brinkmann A.O., Boersma W.J. Localization of androgen receptors in human skin by immunohistochemistry implications for the hormonal regulation of hair growth, sebaceous glands and sweat glands . J Endocrinol. 133:1992;467-475.
12. Liang T., Hoyer S., Yu R., et al. Immunocytochemical localization of androgen receptors in human skin using monoclonal antibodies against the androgen receptor. J Invest Dermatol. 100:1993;663-666.
13. Itami S., Kurata S., Sonoda T., Takayasu S. Interaction between dermal papilla cells and follicular epithelial cells in vitro effect of androgen . Br J Dermatol. 132:1995;527-532.
14. Schmidt J.B., Lindmaier A., Spona J. Hormone receptors in pubic skin of premenopausal and postmenopausal females. Gynecol Obstet Invest. 30:1990;97-100.
15. Garau J.M., di Paola G.R., Charreau E.H. Estrogen and progesterone receptor assays on the vulvar epithelium. J Reprod Med. 31:1986;987-991.