Azidothymidine promotes free radical generation by activated macrophages and hydrogen peroxide-iron-mediated oxidation in a cell-free system

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1688, Issue 3, 2004, Pages 257-264

  Komarov, Andrei M ^a   Hall, Jonathon M ^a   Weglicki, William B ^a  

^a GEORGE WASHINGTON UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Azidothymidine; Azidothymidine, 3 azido 3 deoxythymidine; AZT; AZT glucuronide; AZT phosphate; AZT MP; Chemically deacetylated 2 ,7 dichlorodihydrofluorescein; Free radical; Oxidative stress; Zidovudine

Indexed keywords

3' AMINO 3' DEOXYTHYMIDINE; CATALASE; DEFEROXAMINE MESYLATE; DICHLOROFLUORESCEIN; ENZYME INHIBITOR; HYDROGEN PEROXIDE; IRON COMPLEX; LATEX; PEROXIDASE; SODIUM AZIDE; THYMIDINE; THYMIDINE PHOSPHATE; UNCLASSIFIED DRUG; ZIDOVUDINE; ZIDOVUDINE DERIVATIVE; ZIDOVUDINE GLUCURONIDE; ZIDOVUDINE MONOPHOSPHATE; ZIDOVUDINE TRIPHOSPHATE TETRALITHIUM;

ANIMAL CELL; ARTICLE; CELL FREE SYSTEM; CONCENTRATION (PARAMETERS); DEACETYLATION; IN VITRO STUDY; MACROPHAGE ACTIVATION; NONHUMAN; OXIDATION; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; RAT;

ANIMALS; ANTI-HIV AGENTS; CELL-FREE SYSTEM; FREE RADICALS; HYDROGEN PEROXIDE; IRON; MACROPHAGE ACTIVATION; MACROPHAGES, PERITONEAL; MALE; OXIDATION-REDUCTION; RATS; RATS, SPRAGUE-DAWLEY; RESPIRATORY BURST; THYMINE NUCLEOTIDES; ZIDOVUDINE;

EID: 1842577842     PISSN: 09254439     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbadis.2003.12.012     Document Type: Article

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