Industrial synthesis of 4-chloro, 11β-arylestradiol: How to circumvent a poor diastereoselectivity

Organic Process Research and Development

Volumn 8, Issue 2, 2004, Pages 219-228

  Prat, Denis ^a   Benedetti, Françoise ^a   Girard, Gilles Franc ^a   Bouda, Lahlou Nait ^a   Larkin, John ^a   Wehrey, Christian ^a   Lenay, Jacques ^a  

^a SANOFI   (France)

Author keywords

[No Author keywords available]

Indexed keywords

11BETA ARYL 17ALPHA METHYLESTRADIOL; 4 CHLORO 11BETA ARYLESTRADIOL; COPPER DERIVATIVE; EPOXIDE; ESTRADIOL DERIVATIVE; ESTRONE DERIVATIVE; POLYCYCLIC AROMATIC HYDROCARBON DERIVATIVE; UNCLASSIFIED DRUG;

AROMATIZATION; ARTICLE; ARYLATION; CATALYSIS; CHLORINATION; DRUG STRUCTURE; DRUG SYNTHESIS; HYDROLYSIS; ISOMERISM; STEREOCHEMISTRY; STRUCTURE ANALYSIS; TECHNIQUE;

EID: 1842558917     PISSN: 10836160     EISSN: None     Source Type: Journal    
DOI: 10.1021/op0341622     Document Type: Article

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