Steroidal affinity labels of the estrogen receptor. 3. Estradiol 11β- n-alkyl derivatives bearing a terminal electrophilic group: Antiestrogenic and cytotoxic properties

Journal of Medicinal Chemistry

Volumn 40, Issue 14, 1997, Pages 2217-2227

  Lobaccaro, Carole ^a   Pons, Jean François ^a   Duchesne, Marie Josèphe ^a   Auzou, Gilles ^a   Pons, Michel ^a   Nique, François ^b   Teutsch, Georges ^b   Borgna, Jean Louis ^a  

^a INSERM   (France)

^b SANOFI   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ESTRADIOL; ESTRADIOL DERIVATIVE; ESTROGEN RECEPTOR;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BINDING AFFINITY; BREAST CANCER; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; HUMAN; HUMAN CELL;

AFFINITY LABELS; ALKYLATION; ANIMALS; BREAST NEOPLASMS; CELL SURVIVAL; CLONE CELLS; ESTRADIOL; ESTROGEN ANTAGONISTS; ESTROGENS; FEMALE; HUMANS; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; RECEPTORS, ESTROGEN; RECOMBINANT FUSION PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION; TUMOR CELLS, CULTURED; VITELLOGENINS; XENOPUS;

EID: 0030739230     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm970019l     Document Type: Article

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