Osteoblasts and Osteocytes Express MMP2 and -8 and TIMP1, -2, and -3 Along with Extracellular Matrix Molecules during Appositional Bone Formation

Anatomical Record - Part A Discoveries in Molecular, Cellular, and Evolutionary Biology

Volumn 277, Issue 2, 2004, Pages 262-271

  Hatori, Kouki ^a   Sasano, Yasuyuki ^a   Takahashi, Ichiro ^a   Kamakura, Shinji ^b   Kagayama, Manabu ^a   Sasaki, Keiichi ^a  

^a TOHOKU UNIVERSITY   (Japan)

^b TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Bone; Extracellular matrix; Matrix metalloproteinases; Osteoblast; Osteocyte; Rat; Tissue inhibitors of metalloproteinases

Indexed keywords

COLLAGEN TYPE 1; COLLAGENASE 3; GELATINASE A; MATRIX METALLOPROTEINASE; NEUTROPHIL COLLAGENASE; OSTEOCALCIN; OSTEOPONTIN; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TISSUE INHIBITOR OF METALLOPROTEINASE 3;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BONE DEVELOPMENT; BONE MATRIX; ENZYME ACTIVITY; ENZYME DEGRADATION; EXTRACELLULAR MATRIX; IN SITU HYBRIDIZATION; MALE; NONHUMAN; OSSIFICATION; OSTEOBLAST; OSTEOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

EID: 1842457814     PISSN: 0003276X     EISSN: None     Source Type: Journal    
DOI: 10.1002/ar.a.20007     Document Type: Article

References (45)

1. Aimes RT, Quigley JP. 1995. Matrx metalloproteinase-2 is an interstitial collagenase. J Biol Chem 270:5852-5876.
2. Airora K, Ahonen M, Johansson I, Heikkilä P, Kere J, Kähäri V-M, Saarialho-Kere U. 1998. Human TIMP-3 is expressed during fetal development, hair growth cycle, and cancer progression. J Histochem Cytochem 46:437-447.
3. Birkedal-Hansen H, Moore WGI, Bodden MK, Windsor LJ, Birkedal-Hansen B, DeCarlo A, Enger JA. 1993. Matrixmetalloproteinases: a review. Crit Rev Oral Biol Med 4:197-250.
4. Bord S, Horner A, Hembry RM, Compston JE. 1998. Stromelysin-1 (MMP-3) and Stromelysin-2 (MMP-10) expression in developing human bone: potential roles in skeletal development. Bone 23:7-12.
5. Bord S, Horner A, Beeton CA, Hembry RM, Compston JE. 1999. Tissue inhibitor of matrix metaloproteinase-1 (TIMP-1) distribution in normal and pathological human bone. Bone 24:229-235.
6. Boyde A, Jones SJ. 1985. Bone modelling in the implantation bed. J Biomed Mater Res 19:199-224.
7. Chang C, Werb Z. 2001. The many faces of metalloproteinases: cell growth, invasion, angiogenesis and metastasis. Trends Cell Biol 11:37-43.
8. Caplan AI. 2002. In vivo remodeling. Ann NY Acad Sci 961:307-308.
9. Caplan AI. 2003. Embryonic development and the principles of tissue engineering. Novartis Found Symp 249:17-25.
10. Chin JR, Werb Z. 1997. Matrix metalloproteinases regulate morphogenesis, migration and remodeling of epithelium, tongue skeletal muscle and cartilage in the mandibular arch. Development 124: 1519-1530.
11. Cohen MM. 1993. Sutural biology and the correlates of craniosynostosis. Am J Med Gen 47:581-616.
12. Davies JE. 1996. In vitro modeling of the bone/implant interface. Anat Rec 245:426-445.
13. Dew G, Murphy G, Stanton H, Vallon R, Angel P, Reynolds JJ, Hembry RM. 2000. Localisation of matrix metalloproteinases and TIMP-2 in resorbing mouse bone. Cell Tissue Res 299:385-394.
14. Freemont AJ, Hampson V, Tilman R, Goupille P, Taiwo Y, Hoyland JA. 1997. Gene expression of matrix metalloproteinases 1, 3 and 9 by chondrocytes in osteoarthritic human knee articular cartilage is zone and grade specific. Ann Rheum Dis56:542-549.
15. Gack S, Vallon R, Schmidt J, Grigoriadis A, Tuckermann J, Schenkel J, Weiher H, Wagner EF, Angel P. 1995. Expression of interstitial collagenase during skeletal development of the mouse is restricted to osteoblast-like cells and hypertrophic chondrocytes. Cell Growth Differ 6:759-767.
16. Gomez DE, Alonso DF, Yoshiji H, Thorgeirsson UP. 1997. Tissue inhibitors of metalloproteinases: structure, regulation, and biological functions. Eur J Cell Biol 74:111-122.
17. Gorski JP. 1998. Is all bone the same? distinctive distributions and properties of non-collagenous matrix proteins in lamellar vs. woven bone imply the existence of different undelying osteogenic mechanisms. Crit Rev Oral Biol Med 9:201-223.
18. Herring SW. 1993. Epigenetic and functional influences on skull growth. In: Hanken J, Hall BK, editors. The vertebrate skull, vol. 1. Chicago: University of Chicago Press. p 153-206.
19. Hirakawa K, Hirota S, Ikeda T, Yamaguchi A, Takemura T, Nagoshi J, Yoshiki S, Suda T, Kitamura Y, Nomura S. 1994. Localization of the mRNA for bone matrix proteins during fracture healing as determined by in situ hybridization. J Bone Miner Res 9:1551-1557.
20. Holmbeck K, Bianco P, Caterina J, Yamada S, Kromer M, Kuznetsov SA, Mankani M, Robey PG, Poole AR, Pidoux I, Ward JM, Birkedal-Hansen H. 1999. MT1-MMP-deficient mice develop dwarfism, osteopenia, arthritis, and connective tissue disease due to inadequate collagen turnover. Cell 99:81-92.
21. Jee WWS. 1988. The skeletal tissues. In: Weiss L, editor. Cell and tissue biology, 6th ed. Munich: Urban and Schwarzenburg. p 211-254.
22. Jeffrey JJ. 1998. Collagenase 3. In: Barrett AJ, Rawlings ND, Wosssner JF, editors. Handbook of proteolytic enzyme. San Diego: Academic Press. p 1167-1170.
23. Johansson N, Saarialho-Kere U, Airora K, Herva R, Nissinen L, Westermarck J, Vuorio E, Heino J, Kähäri V-M. 1997. Collagenase-3(MMP-13) is expressed by hypertrophic chondrocytes, periosteal cells, and osteoblasts during human fetal bone development. Dev Dyn 206:367-397.
24. Kamakura S, Sasano Y, Homma-Ohki H, Nakamura M, Suzuki O, Kagayama M, Motegi K. 1997. Multinucleated giant cell srecruited by implantation of octacalcium phosphate (OCP) in rat bone marrow share ultrastructural characteristics with osteoclasts. J Electron Microsc 46:397-403.
25. Kamakura S, Sasano Y, Homma H, Suzuki O, Kagayama M, Motegi K. 1999. Implantation of octacalcium phosphate (OCP) in rat skull defects enhances bone repair. J Dent Res 78:1682-1687.
26. Kamakura S, Sasano Y, Homma H, Suzuki O, Kagayama M, Motegi K. 2001. Implantation of octacalcium phosphate nucleates isolated bone formation in rat skull defects. Oral Dis 7:259-265.
27. Karaplis AC. 2002. Embryonic development of bone and the molecular regulation of intramembranous and endochondral bone formation. In: Bilezikian JP, Raisz LG, Rodan GA, editors. Principles of bone biology, 2nd ed. San Diego: Academic Press. p 33-58.
28. Kawashima-Ohya Y, Satakeda H, Kurata Y, Kawamoto T, Yan W, Akagawa Y, Hayakawa T, Noshiro M, Okada Y, Nakamura S, Kato Y. 1998. Effects of parathroid hormone (PTH) and PTH-related peptide on expressions of matrix matalloproteinase-2, -3, and -9 in growth plate chondrocytes cultures. Endocrinology 139:2120-2127.
29. Kieswetter K, Schwartz Z, Dean DD, Boyan BD. 1996. The role of implant surface characteristics in the healing of bone. Crit Rev Oral Biol Med 7:329-345.
30. Mattot V, Raes MB, Henriet P, Eeckhout Y, Stehelin D, Vandenbunder B, Desbiens X. 1995. Expression of interstitial collagenase is restricted to skeletal tissue during mouse embryogenesis. J Cell Sci 108:529-535.
31. Murai K, Takeshita F, Ayukawa Y, Kiyoshima T, Suetsugu T, Tanaka T. 1996. Light and electron microscopic studies of bone-implant interface in the tibiae of young and mature rats. J Biomed Mater Res 30:523-533.
32. Nagase H, Woessner JF. 1999. Matrix metalloproteinases. J Biol Chem 274:21491-21494.
33. NIH Animal Research Advisory Committee. 1995. Using animals in intramural research Guidelines for investigators and Guidelines for animal users.
34. Nomura S, Wills AJ, Edwards DR, Heath JK, Hogan BLM. 1988. Developmental expression of 2ar(osteopontin) and SPARK(osteonectin) RNA as revealed by in situ hybridization. J Cell Biol 106:441-450.
35. Puleo DA, Nanci A. 1999. Understanding and controlling the bone-implant interface. Biomaterials 20:2311-2321.
36. Sasano Y, Kamakura S, Nakamura M, Suzuki O, Mizoguchi I, Akita H, Kagayama M. 1995. Subperiosteal implantation of octacalcium phosphate(OCP) stimulates both chondrogenesis and osteogenesis in the tibia, but only osteogenesis in the parietal bone of a rat. Anat Rec 242:40-46.
37. Sasano Y, Kamakura S, Homma H, Suzuki O, Mizoguchi I, Kagayama M. 1999. Implanted octacalcium phosphate(OCP) stimulates osteogenesis by osteoblastic cells or committed osteoprogenitors in rat calvarial periosteum. Anat Rec 256:1-6.
38. Sasano Y, Li HC, Zhu JX, Imanaka-Yoshida K, Mizoguchi I, Kagayama M. 2000a. Immunohistochemical localization of type I collagen, fibronectin, and tenascin C during embryonic osteogenesis in the dentary of mandibles and tibias in rats. Histochem J 32:591-598.
39. Sasano Y, Zhu JX, Kamakura S, Kusunoki S, Mizoguchi I, Kagayama M. 2000b. Expression of major bone extracellular matrix proteins during embryonic osteogenesis in rat mandibles. Anat Embryol 202:31-37.
40. Sasano Y, Maruya Y, Sato H, Zhu JX, Takahashi I, Mizoguchi I, Kagayama M. 2001. Distinctive expression of extracellular matrix molecules at mRNA and protein levels during formation of cellular and acellular cementum in the rat. Histochem J 33:91-99.
41. Sasano Y, Zhu JX, Tsubota M, Takahashi I, Onodera K, Mizoguchi I, Kagayama M. 2002. Gene expression of MMP8 and MMP13 during embryonic development of bone and cartilage in the rat mandible and hind limb. J Histochem Cytochem 50:325-332.
42. Shimizu T, Sasano Y, Nakajo S, Kagayama M, Shimauchi H. 2001. Osteoblastic differentiation of periosteum-derived cells is promoted by the physical contact with the bone matrix in vivo. Anat Rec 264:72-81.
43. Woessner JF. 1998. The matrix metalloproteinase family. In: Parks WC, Mecham RP, editors. Matrix metalloproteinases. San Diego: Academic Press. p 1-14.
44. Woessner JF, Nagase H. 2000. Matrix metalloproteinases and TIMPs. Oxford: Oxford University Press.
45. Zhu JX, Sasano Y, Takahashi I, Mizoguchi I, Kagayama M. 2001. Temporal and spatial gene expression of major bone extracellular matrix molecules during embryonic mandibular osteogenesis in rats. Histochem J 33:25-35.