Halogenoalkyl isocyanates as bifunctional reagents in an Aza-Wittig/heterocyclization reaction on the solid phase: Efficient entry into new tetracyclic benzimidazole systems

Journal of Combinatorial Chemistry

Volumn 6, Issue 2, 2004, Pages 220-223

  Hoesl, Cornelia E ^a   Nefzi, Adel ^a   Houghten, Richard A ^a  

^a TORREY PINES INSTITUTE FOR MOLECULAR STUDIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

8 (AMINOCARBONYL) 1 (2 BROMOETHYL) 11 HEXYL 5 OXO 2,3 DIHYDRO 1H IMIDAZO[2',1':4,5][1,3,5]TRIAZINO[1,2 A]BENZIMIDAZOL 11 IUM TRIFLUOROACETATE; 8 (AMINOCARBONYL) 1 (2 CHLOROETHYL) 11 (3 METHOXYPROPYL) 5 OXO 2,3 DIHYDRO 1H IMIDAZO[2',1':4,5][1,3,5]TRIAZINO[1,2 A]BENZIMIDAZOL 12 IUM TRIFLUOROACETATE; 8 (AMINOCARBONYL) 1 (2 CHLOROETHYL) 11 CYCLOHEXYL 5 OXO 2,3 DIHYDRO 1H IMIDAZO[2',1':4,5][1,3,5]TRIAZINO[1,2 A]BENZIMIDAZOL 11 IUM TRIFLUOROACETATE; 8 (AMINOCARBONYL) 1 (2 CHLOROETHYL) 11 HEXYL 5 OXO 2,3 DIHYDRO 1H IMIDAZO[2',1':4,5][1,3,5]TRIAZINO[1,2 A]BENZIMIDAZOL 11 IUM TRIFLUOROACETATE; 8 (AMINOCARBONYL) 1 [2 (BUTYLAMINO)ETHYL] 11 HEXYL 5 OXO 2,3 DIHYDRO 1H IMIDAZO[2',1':4,5][1,3,5]TRIAZINO[1,2 A]BENZIMIDAZOL 11 IUM TRIFLUOROACETATE; 8 (AMINOCARBONYL) 11 BUTYL 1 (2 CHLOROETHYL) 5 OXO 2,3 DIHYDRO 1H IMIDAZO[2',1':4,5][1,3,5]TRIAZINO[1,2 A]BENZIMIDAZOL 11 IUM TRIFLUOROACETATE; 9 (AMINOCARBONYL) 1 (3 CHLOROPROPYL) 12 CYCLOHEXYL 6 OXO 1,2,3,4 TETRAHYDROPYRIMIDO[2',1':4,5][1,3,5]TRIAZINO[1,2 A]BENZIMIDAZOL 12 IUM TRIFLUOROACETATE; BENZIMIDAZOLE DERIVATIVE; ISOCYANIC ACID DERIVATIVE; REAGENT; UNCLASSIFIED DRUG;

ARTICLE; AZA WITTIG REACTION; CHEMICAL REACTION; DRUG STRUCTURE; DRUG SYNTHESIS; HETEROCYCLIZATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SOLID; STRUCTURE ANALYSIS; SUBSTITUTION REACTION; X RAY ANALYSIS;

ALKYLATION; BENZIMIDAZOLES; CRYSTALLOGRAPHY, X-RAY; CYCLIZATION; HALOGENS; ISOCYANATES; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, CHEMICAL; MOLECULAR STRUCTURE; POLYCYCLIC COMPOUNDS; RESINS, SYNTHETIC; STEREOISOMERISM;

EID: 1842454317     PISSN: 15204766     EISSN: None     Source Type: Journal    
DOI: 10.1021/cc030036y     Document Type: Article

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