Potential use of 2-hydroxypropyl-β-cyclodextrin as a release modifier of a water-soluble drug, metoprolol tartrate, from ethylcellulose tablets

Journal of Drug Delivery Science and Technology

Volumn 14, Issue 1, 2004, Pages 69-76

  Ikeda, Y ^a   Motoune, S ^a   Ono, M ^a   Arima, H ^b   Hirayama, F ^b   Uekama, K ^b  

^a WAKUNAGA PHARMACEUTICAL CO LTD   (Japan)

^b KUMAMOTO UNIVERSITY   (Japan)

Author keywords

2 Hydroxypropyl cyclodextrin; Ethylcellulose; Gel formation; Metoprolol tartrate; Release control

Indexed keywords

2 HYDROXYPROPYL BETA CYCLODEXTRIN; ETHYL CELLULOSE; METOPROLOL TARTRATE;

APPARATUS; ARTICLE; CALCULATION; COMPLEX FORMATION; CONTROLLED DRUG RELEASE; DIFFUSION; DISPERSION; DRUG PENETRATION; DRUG SOLUBILITY; DRUG STORAGE; GELATION; HYDROPHOBICITY; PH; POROSITY; SOLID; STOICHIOMETRY; TABLET; TEMPERATURE DEPENDENCE; VISCOSITY;

EID: 1842451402     PISSN: 11571489     EISSN: None     Source Type: Journal    
DOI: 10.1016/s1773-2247(04)50008-4     Document Type: Article

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