The association of age and elimination of isoniazid: An example of median regression with heteroscedasticity

South African Statistical Journal

Volumn 37, Issue 2, 2003, Pages 191-202

  Maritz, J S ^a   Donald, P R ^b   Schaaf, H S ^b   Seifart, H I ^c   Parkin, D P ^c   Werele, C ^b  

^a SOUTH AFRICAN MEDICAL RESEARCH COUNCIL   (South Africa)

^b STELLENBOSCH UNIVERSITY   (South Africa)

^c UNIVERSITY OF STELLENBOSCH   (South Africa)

Author keywords

Estimating equations; Gradient estimation; Heteroscedasticity; Median regression

Indexed keywords

EID: 1842430762     PISSN: 0038271X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

1. BROWN, B.M. (1985). Multiparameter linearization theorems. J. Roy. Statist. Soc.(B), 47, 323-331.
2. FOX, H.H. (1952). The chemical approach to the control of tuberculosis. Science, 116, 129-134.
3. HUGHES, H.B. (1953). On the metabolic rate of Isoniazid. J. Pharmacol. Exp. Ther., 109, 444-452.
4. MITCHISON, D.A. (2000). Role of individual drugs in the chemotherapy of tuberculosis. Int. J. Tuberc. Lung Dis., 4, 796-806.
5. PARKIN, D.P., VANDENPLAS, S., BOTHA, F.J.H. et al. (1997). Trimodality of isoniazid elimination. Am. J. Respir. Crit. Care Med., 155, 1717-1722.
6. PARZEN, E. (1962). On estimation of a probability density function and mode. Ann. Math. Statist., 33, 1065-1076.
7. SCHMIDT, L.H. (1962). The problem of the rapid inactivator of isoniazid. Bull. Int. Union Tuberc., 32, 487-502.
8. STAUDTE, R.G. & SHEATHER, S. J. (1990). Robust Estimation and Testing. Wiley. New York.