Effects of Oral Adsorbent AST-120 in Patients with Chronic Renal Failure with or without Diabetes

Renal Failure

Volumn 26, Issue 1, 2004, Pages 99-101

  Nakamura, Tsukasa ^a   Kawagoe, Yasuhiro ^a   Ueda, Yoshihiko ^b   Ebihara, Isao ^c   Koide, Hikaru ^c  

^a Shinmatsudo Central General Hospital   (Japan)

^b DOKKYO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c KOTO HOSPITAL   (Japan)

Author keywords

Chronic renal failure; Diabetes; Oral adsorbent AST 120

Indexed keywords

AST 120;

ADULT; CHRONIC KIDNEY FAILURE; CONTROLLED STUDY; DIABETES MELLITUS; DIABETIC NEPHROPATHY; FEMALE; HUMAN; LETTER; MAJOR CLINICAL STUDY; MALE; MOLECULAR MECHANICS; PRIORITY JOURNAL; STATISTICAL ANALYSIS;

EID: 1842429484     PISSN: 0886022X     EISSN: None     Source Type: Journal    
DOI: 10.1081/JDI-120028563     Document Type: Letter

References (8)

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2. Aoyama, I.; Shimokata, K.; Niwa, T. An oral adsorbent down regulates renal expression of genes that promote interstitial inflammation and fibrosis in diabetic rats. Nephron 2002, 92, 635-651.
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4. Niwa, T.; Nomura, T.; Sugiyama, S.; Miyazaki, T.; Tsukushi, S.; Tsutsui, S. The protein metabolite hypothesis, a model for the progression of renal failure: an oral adsorbent lowers indoxyl sulfate levels in undialyzed uremic patients. Kidney Int. 1997, 52 (suppl 62), S23-S28.
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6. Tsubakihara, Y.; Takabatake, Y.; Oka, K.; Shoji, T.; Togawa, M.; Okada, N.; Takahito, I.; Imai, E. Effects of the oral adsorbent AST-120 on tryptophan metabolism in uremic patients. Am. J. Kidney Dis. 2003, 41 (suppl 2), S38-S41.
7. Aoyama, I.; Enomoto, A.; Niwa, T. Effects of oral adsorbent on gene expression profile in uremic rat kidney: cDNA array analysis. Am. J. Kidney Dis. 2003, 41 (suppl 2), S8-S14.
8. Yorioka, N.; Ito, T.; Masaki, T.; Ogata, S.; Asakimori, Y.; Tanji, C.; Kyuden, Y.; Komiya, Y.; Kumagai, J.; Taniguchi, Y.; Kohno, N. Dose-dependent effect of an oral adsorbent, AST-120, in patients with early chronic renal failure. J. Int. Med. Res. 2002, 30, 467-475.