Killing two birds with one RKIP

Trends in Endocrinology and Metabolism

Volumn 15, Issue 3, 2004, Pages 91-92

  Goel, Reema ^a   Baldassare, Joseph J ^a  

^a SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; CYCLIC AMP DEPENDENT PROTEIN KINASE; G PROTEIN COUPLED RECEPTOR KINASE 2; GUANINE NUCLEOTIDE BINDING PROTEIN; ISOPRENALINE; MEMBRANE RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHATIDYLETHANOLAMINE BINDING PROTEIN; PHOSPHOTRANSFERASE; PROTEIN KINASE C; RAF PROTEIN; RECEPTOR; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

BASAL CELL; CELL STIMULATION; CYTOPLASM; DISSOCIATION; ENZYME ACTIVATION; HUMAN; METASTASIS; NEUROTRANSMISSION; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN PHOSPHORYLATION; RECEPTOR DOWN REGULATION; SHORT SURVEY; SIGNAL TRANSDUCTION; STIMULATION; WILD TYPE;

ANDROGEN-BINDING PROTEIN; ANIMALS; HUMANS; MALE; PHOSPHATIDYLETHANOLAMINE BINDING PROTEIN; PHOSPHORYLATION;

EID: 1842418691     PISSN: 10432760     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tem.2004.02.004     Document Type: Short Survey

References (6)

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2. Yeung K., et al. Mechanism of suppression of the Raf/MEK/extracellular signal-regulated kinase pathway by the Raf kinase inhibitor protein. Mol. Cell. Biol. 20:2000;3079-3085.
3. Fu Z., et al. Effects of Raf kinase inhibitor protein expression on suppression of prostate cancer metastasis. J. Natl. Cancer Inst. 95:2003;878-889.
4. Corbit K.C., et al. Activation of Raf-1 signaling by protein kinase C through a mechanism involving Raf kinase inhibitory protein. J. Biol. Chem. 278:2003;13061-13068.
5. Lorenz K., et al. Protein kinase C switches the Raf kinase inhibitor from Raf-1 to GRK-2. Nature. 426:2003;574-579.
6. Krasel C., et al. Phosphorylation of GRK2 by protein kinase C abolishes its inhibition by calmodulin. J. Biol. Chem. 276:2001;1911-1915.