Inhibition of recombinant human neutrophil collagenase by doxycycline is pH dependent

Journal of Rheumatology

Volumn 24, Issue 9, 1997, Pages 1769-1773

  Smith Jr , Gerald N ^a   Brandt, Kenneth D ^a   Mickler, Elizabeth A ^a   Hasty, Karen A ^b  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Univ Tennessee Ctr the Hlth Sci   (United States)

Author keywords

Collagenase; Doxycycline; pH

Indexed keywords

COLLAGEN TYPE 2; COLLAGENASE; DOXYCYCLINE; ENZYME PRECURSOR; TRYPSIN;

ARTICLE; ARTICULAR CARTILAGE; COLORIMETRY; CONTROLLED STUDY; DRUG BINDING; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME INHIBITION; ENZYME STABILITY; ENZYME SYNTHESIS; EXTRACELLULAR MATRIX; HYDROLYSIS; MOLECULAR WEIGHT; NEUTROPHIL; OSTEOARTHRITIS; PH; PRIORITY JOURNAL;

ANTI-BACTERIAL AGENTS; BLOTTING, WESTERN; COLLAGENASES; DOXYCYCLINE; ENZYME INHIBITORS; HUMANS; HYDROGEN-ION CONCENTRATION; MATRIX METALLOPROTEINASE 8; NEUTROPHILS; PHENYLMERCURIC ACETATE; RECOMBINANT PROTEINS;

EID: 1842405998     PISSN: 0315162X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

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