Transcription of genes encoding iron and heme acquisition proteins of Haemophilus influenzae during acute otitis media

Infection and Immunity

Volumn 65, Issue 11, 1997, Pages 4696-4700

  Whitby, Paul W ^a   Sim, Kim Eng ^a   Morton, Daniel J ^a   Patel, Janak A ^a   Stull, Terrenck L ^a,b,c  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

^c CHO 2B300 ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; HEME; HEMOGLOBIN; HEMOPEXIN; IRON BINDING PROTEIN; TRANSFERRIN;

ARTICLE; CHILD; GENETIC TRANSCRIPTION; HAEMOPHILUS INFLUENZAE; HUMAN; INFANT; OTITIS MEDIA; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 1842372027     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.65.11.4696-4700.1997     Document Type: Article

References (45)

1. Becker-Andre, M. 1993. Absolute levels of mRNA by polymerase chain reaction-aided transcript titration assay. Methods Enzymol. 218:420-445.
2. Bezkorovainy, A. 1987. Iron proteins, p. 27-68. In J. J. Bullen and E. Griffiths (ed.). Iron and infection: molecular, physiological and clinical aspects. John Wiley & Sons. New York. N.Y.
3. Bluestone, C. D., and J. O. Klein. 1995. Anonymous otitis media in infants and children. W. B. Saunders Company. Philadelphia. Pa.
4. Brown, M. R., H. Anwar, and P. A. Lambert. 1984. Evidence that mucoid Pseudomonas aeruginosa in cystic fibrosis lung grows under iron-restricted conditions. FEMS Microbiol. Lett. 21:113-117.
5. Chonmaitree, T., V. M. Howie, and A. L. Truant. 1986. Presence of respiratory viruses in middle ear fluids and nasal wash specimens from children with acute otitis media. Pediatrics 77:698-702.
6. Cope, L. D., R. Yogev, U. Muller-Eberhard, and E. J. Hansen. 1995. A gene cluster involved in the utilization of both free heme and heme:hemopexin by Haemophilus tnfluenzae type b. J. Bacteriol. 177:2644-2653.
7. Evans, N. M., D. D. Smith, and A. J. Wicken. 1974. Haemin and nicotinamide adenine dinucleotide requirements of Haemophilus influenzae and Haemophilus parainfluenzae. J. Med. Microbiol. 7:359-365.
8. Falla, T. J., S. R. Dobson, D. W. Crook, W. A. Kraak, W. W. Nichols, E. C. Anderson, J. Z. Jordens, M. P. Slack, E. Mayon-White, and E. R. Moxon. 1993. Population-based study of non-typeable Haemophilus influenzae invasive disease in children and neonates. Lancet 341:851-854.
9. Fernandez-Beros, M. E., C. Gonzalez, M. A. McIntosh, and F. C. Cabello. 1989. Immune response to the iron-deprivation-induced proteins of Salmonella typhi in typhoid fever. Infect. Immun. 57:1271-1275.
10. Ferreiros, C. M., L. Ferron, and M. T. Criado. 1994. In vivo human immune response to transferrin-binding protein 2 and other iron-regulated proteins of Neisseria meningitidis. FEMS Immunol. Med Microbiol. 8:63-68.
11. Fleischmann, R. D., M. D. Adams, O. White, R. A. Clayton, E. F. Kirkness, A. R. Kerlavage, C. J. Bult, J. Tomb, B. A. Dougherty, J. M. Merrick, K. McKenney, G. Sutton, W. FitzHugh, C. Fields, J. D. Gocayne, J. Scott, R. Shirley, L. Liu, A. Glodek, J. M. Kelley, J. F. Weidman, C. A. Phillips, T. Spriggs, E. Hedblom, M. D. Cotton, R. C. Utterback, M. C. Hanna, D. T. Nguyen, D. M. Saudek, R. C. Brandon, L. D. Fine, J. L. Fritchman, J. L. Fuhrmann, N. S. M. Geoghagen, C. L. Gnehm, L. A. McDonald, K. V. Small, C. M. Fraser, H. O. Smith, and J. C. Venter. 1995. Whole-genome random sequencing and assembly of Haemophilus influenzae Rd. Science 269:496-512.
12. Frangipane, M. E., D. J. Morton, J. A. Wooten, J. M. Pozsgay, and T. L. Stull. 1994. Binding of human hemoglobin by Haemophilus influenzae. FEMS Microbiol. Lett. 118:243-248.
13. Giebink, G. S., P. B. Betalden, J. N. Rose, and C. T. Le. 1984 Cefaclor versus amoxicillin in the treatment of acute otits media. Am. J. Dis. Child. 138: 287-292.
14. Gray-Owen, S. D., and A. B. Schryvers. 1995. Characterization of transferrin binding proteins 1 and 2 in invasive type b and nontypeable strains of Haemophilus influenzae. Infect. Immun. 63:3809-3815.
15. Griffiths, E., and J. Humphreys. 1980. Isolation of enterochelin from the peritoneal washings of guinea pigs lethally infected with Escherichia coli. Infect. Immun. 28:286-289.
16. Griffiths, E., P. Stevenson, R. Thorpe, and H. Chart. 1985. Naturally occurring antibodies in human sera that react with the iron-regulated outer membrane proteins of Escherichia coli. Infect. Immun. 47:808-813.
17. Haas, B., J. Kraut, J. Marks, S. C. Zanker, and D. Castignetti. 1991. Siderophore presence in sputa of cystic fibrosis patients. Infect. Immun. 59: 3997-4000.
18. Holland, J., P. R. Langford, K. J. Towner, and P. Williams. 1992. Evidence for in vivo expression of transferrin-binding proteins in Haemophilus influenzae type b. Infect. Immun. 60:2986-2991.
19. Holodniy, M. 1994. Clinical application of reverse transcription-polymerase chain reaction for HIV infection. Clin. Lab. Med. 14:335-349.
20. Jin, H., Z. Ren, J. M. Pozsgay, C. Elkins, P. W. Whitby, D. J. Morton, and T. L. Stull. 1996. Cloning of a DNA fragment encoding a heme-repressible hemoglobin-binding outer membrane protein from Haemophilus influence Infect. Immun. 64:3134-3141.
21. Kostman, J. R., B. L. Sherry, C. L. Flinger, S. Egaas, P. Sheeran, L. Baken, J. E. Bauwens, C. Clausen, D. M. Sherer, J. J. Plorde, T. L. Stull, and P. M. Mendelmen. 1993. Invasive Haemophilus influenzae infections in older children and adults in Seattle. Clin. Infect Dis. 17:389-396.
22. Lee, B. C. 1995. Quelling the red menace: haem capture by bacteria. Mol. Microbiol. 18:383-390.
23. Lee, B. C. 1992. Isolation of an outer membrane hemin-binding protein of Haemophilus influence type b. Infect Immun. 60:810-816.
24. Lehker, M. W., and J. F. Alderete. 1992. Iron regulates growth of Trichomonas vaginalis and the expression of immunogenic trichomonad proteins. Mol. Microbiol. 6:123-132.
25. Li, Z., B. Foiry, and M. Jacques. 1995. Growth of Serpulina (Treponema) hyodysenteriae under iron-restricted conditions. Can. J. Vet. Res. 59:149-153.
26. Litwin, C. M., and S. B. Calderwood. 1993 Role of iron in regulation of virulence genes. Clin. Microbiol. Rev. 6:137-149.
27. Maciver, L, J. L. Latimer, H. H. Liem, V. Muller-Eberhard, Z. Hrkal, and E. J. Hansen. 1996. Identification of an outer membrane protein involved in utilization of hemoglobin-haptoglobin complexes by nontypeable Haemophilus influenzae. Infect. Immun. 64:3703-3712.
28. Madorne, D. V., C. L. Johnson, D. C. Phipps, Pennridge Pediatric Associates, L A. Popejoy, R. Eby, and D. H. Smith. 1990 Safety and immunologic response to Haemophilus influenzae type b oligosaccharide-CRM197 conjugate vaccine in 1 to 6-month-old infants. Pediatrics 85:331-337.
29. Masked, D. J., M. J. Szabo, P. D. Butler, A. E. Williams, and E. R. Moxon. 1991. Molecular analysis of a complex locus from Haemophilus influenzae involved in phase-variable lipopolysaccharide biosynthesis. Mol. Microbiol. 5:1013-1022.
30. Morton, D. J., J. M. Musser, and T. L. Stull. 1993. Expression of the Haemophilus influenzae transferrin receptor is repressible by hemin but not elemental iron alone. Infect. Immun. 61:4033-4037.
31. Murphy, T. V., K. E. White, and P. Pastor. 1993. Declining incidence of Haemophilus influenzae type b disease since introduction of vaccination. JAMA 269:246-248.
32. Nwankwo, D. L., L. S. Moran, B. E. Slatko, P. A. Waite-Rees, L. F. Dorner, J. S. Benner, and G. G. Wilson. 1994 Cloning, analysis and expression of the HindIII R-M-encoding genes. Gene 150:75-80.
33. Otto, B. R., A. M. Verweij-van Vught, and D. M. MacLaren. 1992. Transferrins and heme-compounds as iron sources for pathogenic bacteria. Crit. Rev. Microbiol. 18:217-233.
34. Peek, R. M., Jr., G. G. Miller, K. T. Tham, G. I. Perez-Perez, T. L. Cover, J. C. Atherton, G. D. Dunn, and M. J. Blaser. 1995. Detection of Helicobacter pylori gene expression in human gastric mucosa. J. Clin. Microbiol. 33:28-32.
35. Pidcock, K. A., J. A. Wooten, B. A. Daley, and T. L. Stull. 1988. Iron acquisition by Haemophilus influenzae. Infect. Immun. 56:721-725.
36. Reidl, J., and J. J. Mekalanos. 1996. Lipoprotein e(P4) is essential for hemin uptake by Haemophilus influenzae. J. Exp. Med. 183:621-629.
37. Sambrook, T., E. F. Fritsrh, and T. Maniatis. 1989 Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press. Cold Spring Harbor, N.Y.
38. Sorensen, C. H., and H. Moller. 1993. Lactoferrin, secretory IgA, and albumin in upper airway secretions from children with secretory otitis media, p. 424-426. In D. J. Lim, C. D. Bluestone, J. O. Klein, J. D. Nelson, and P. L. Ogra (ed.). Recent advances in otitis media. Decker Periodicals, Hamilton, Ontario, Canada.
39. Stull, T. L. 1987. Protein sources of heme for Haemophilus influenzae. Infect. Immun. 55:148-153.
40. Teele, D. W., J. O. Klein, V. Rosner, and The Greater Boston Otitis Media Study Group. 1989. Epidemiology of otitis media during the first seven years of life in children in Greater Boston: a prospective, cohort study. J. Infect. Dis. 160:83-94.
41. Wallace, R. J., D. M. Musher, and R. J. Martin. 1978. Haemophilus influenzae pneumonia in adults. Am. J. Med. 64:87-93.
42. Wang, A. M., M. V. Doyle, and D. F. Mark. 1989. Quantitation of mRNA by the polymerase chain reaction. Proc. Natl. Acad. Sci. USA 86:9717-9721.
43. Wenger, J. D., R. Pierce, K. Deaver, R. Franklin, G. Bosley, N. Pigott, and C. V. Broome. 1992. Invasive Haemophilus influenzae disease: a population-based evaluation of the role of capsular polysaccharide serotype. J. Infect. Dis. 165:S34-S35.
44. Winston, J. L., C. K. Chen, M. E. Neiders, and D. W. Dyer. 1993 Membrane protein expression by Actinobacillus actinomycetemcomitans in response to iron availability. J. Dent. Res. 72:1366-1373.
45. Zhao, G., C. Pijoan, K. Choi, S. K. Maheswaran, and E. Trigo. 1995. Expression of iron-regulated outer membrane proteins by porcine strains of Pasteurella multocida. Can. J. Vet. Res. 59:46-50.