Conformational analysis of two inhibitors of prolyl-endopeptidase: Comparison of 4-phenyl-butyryl- and octanoyl-prolyl-pyrrolidine

Quantitative Structure-Activity Relationships

Volumn 16, Issue 2, 1997, Pages 136-141

  Fehér, Miklós ^a   Kánai, Károly ^a   Podányi, Benjámin ^a   Hermecz, István ^a  

^a CHEMICAL RESEARCH CENTER   (Hungary)

Author keywords

3D QSAR; 4 phenyl butyryl prolyl pyrolidine; Conformational search; NMR; Octanoyl prolyl pyrolidine; PEP inhibitors; Pharmacophore; Propyl endopeptidase inhibitors

Indexed keywords

COMPUTATIONAL CHEMISTRY; PHARMACODYNAMICS;

3D-QSAR; 4-PHENYL-BUTYRYL-PROLYL-PYROLIDINE; CONFORMATIONAL ANALYSIS; CONFORMATIONAL SEARCH; OCTANOYL-PROLYL-PYROLIDINE; PHARMACOPHORES; PROLYL ENDOPEPTIDASE; PROLYL-ENDOPEPTIDASE INHIBITOR; PROPYL-ENDOPEPTIDASE INHIBITOR; PYRROLIDINES;

CONFORMATIONS;

PROLYL ENDOPEPTIDASE INHIBITOR; PYRROLIDINE DERIVATIVE;

ARTICLE; DRUG CONFORMATION; PRIORITY JOURNAL;

EID: 1842331464     PISSN: 09318771     EISSN: None     Source Type: Journal    
DOI: 10.1002/qsar.19970160206     Document Type: Article

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