Activation of the adenylate cyclase-dependent protein kinase pathway increases high affinity glutamate uptake into rat striatal synaptosomes

Neuropharmacology

Volumn 35, Issue 5, 1996, Pages 541-547

  Pisano, P ^a,b   Samuel, D ^b   Nieoullon, A ^b   Kerkerian Le Goff, L ^b  

^a AIX MARSEILLE UNIVERSITY   (France)

^b CNRS   (France)

Author keywords

cAMP; Forskolin; Glutamate uptake; Protein kinase A (PKA); Protein kinase C (PKC); Striatum

Indexed keywords

ADENYLATE CYCLASE; ADENYLATE CYCLASE ACTIVATOR; BUCLADESINE; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; CYCLIC AMP DERIVATIVE; FORSKOLIN; GLUTAMIC ACID; N (2 METHYLAMINOETHYL) 5 ISOQUINOLINESULFONAMIDE; OKADAIC ACID; PHORBOL DIBUTYRATE; PHOSPHOPROTEIN PHOSPHATASE INHIBITOR; PROTEIN KINASE; PROTEIN KINASE A ACTIVATOR; PROTEIN KINASE C; PROTEIN KINASE C ACTIVATOR; RADIOISOTOPE; STAUROSPORINE; UNCLASSIFIED DRUG;

AMINO ACID TRANSPORT; ANIMAL CELL; ARTICLE; BINDING AFFINITY; BRAIN HOMOGENATE; BRAIN SYNAPTOSOME; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORPUS STRIATUM; DRUG INHIBITION; DRUG POTENTIATION; ENZYME ACTIVATION; FEMALE; KINETICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; REGULATORY MECHANISM;

EID: 0030152063     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/0028-3908(96)84624-7     Document Type: Article

References (30)

1. Barbour B., Szatkowski M., Ingledew N., Atwell D. Arachidonic acid induces a prolonged inhibition of glutamate uptake in glial cells. Nature. 342:1989;918-920.
2. Bloc A., Samuel D., Forni C., Dusticier N., Kerkerian-Le Goff L. Effects of ionotropic excitatory aminoacid receptor antagonists on glutamate transport and transport-mediated changes in extracellular excitatory aminoacids in the rat striatum. J. Neurochem. 64:1995;1598-1604.
3. Casado M., Zafra F., Aragon C., Gimenez C. Activation of high affinity uptake of glutamate by phorbol esters in primary glial cell cultures. J. Neurochem. 57(4):1991;1185-1190.
4. Casado M., Benhadan A., Zafra F., Danbolt N., Aragon C., Gimenez C., Kanner B.I. Phosphorylation and modulation of brain glutamate transporters by protein kinase C. J. Biol. Chem. 268(36):1993;27313-27317.
5. Castagna M., Yakai Y., Kaibuchi K., Samo K., Kikkawa V., Nishizuka Y. Direct activation of calcium-activated, phospholipid-dependent protein kinase C by tumor promoter phorbol esters. J. Biol. Chem. 257:1982;7847-7857.
6. Colwell C.S., Levine M.S. Excitatory synaptic transmission in neostriatal neurons: regulation by cyclic AMP-dependent mechanisms. J. Neurosci. 15(3):1995;1704-1713.
7. Corey J.L., Davidson N., Lester H.A., Brecha N., Quick M.W. Protein kinase C modulates the activity of a cloned γ-aminobutyric acid transporter expressed in Xenopus oocytes via regulated subcellular redistribution of the transporter. J. Biol. Chem. 260:1994;14759-14767.
8. Erecinska M. The neurotransmitter aminoacid transport systems. Biochem. Pharmacol. 36(21):1987;3547-3555.
9. Fonnum F. Glutamate: a neurotransmitter in mammalian brain. J. Neurochem. 42(1):1984;1-11.
10. Ford B.D. and Townsel J.G. (1994) Protein Kinase C in Limulus Neuronal Tissues and its Involvement in the Regulation of High Affinity Choline Uptake. Part 1, p. 539. Society for Neuroscience, 24th annual meeting, Miami Beach, Florida, 13-18 November, 1994. Abs. No. 229.8.
11. Gereau R.W., Conn P.J. Potentiation of cAMP responses by metabotropic glutamate receptors depresses excitatory synaptic transmission by a kinase-independent mechanism. Neuron. 12:1994;1121-1129.
12. Gilad G.M., Gilad V.H., Wyatt R.J., Tizabi Y. Region-selective stress-induced increase of glutamate uptake and release in rat forebrain. Brain Res. 525:1990;335-338.
13. Hardie D.G. (1993) Use of protein phosphatase inhibitors in intact cells. In Protein Phosphorylation. A Practical Approach. (Hardie D.G., Ed.), pp. 109-119. IRL Press at Oxford University Press, Oxford.
14. 3H]-staurosporine on various protein kinases. Biochem. Biophys. Res. Comm. 171:1990;189-195.
15. Hidaka H. and Kobayashi R. (1993) Use of protein (serine/threonine) kinase activators and inhibitors to study protein phosphorylation in intact cells. In Protein Phosphorylation. A Practical Approach (Hardie D.G., Ed.), pp. 87-107. IRL Press at Oxford University Press, Oxford.
16. Kanai Y., Smith C.G., Hediger M.A. A new family of neurotransmitter transporters: the high affinity glutamate transporters. FASEB J. 8:1993;1450-1459.
17. Laurenza A., McHugh Sutkowski E., Searmon K.B. Forskolin: a specific stimulator of adenylate cyclase or a diterpene with multiple sites of action? Trends Pharmacol. Sci. 10:1989;442-446.
18. Lowry O.H., Rosebrough N.J., Far A.R., Randall R.J. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193:1951;265-275.
19. McBean G., Roberts P.J. Neurotoxicity of L-glutamate and DL-threo-3-hydroxyaspartate in the rat striatum. J. Neurochem. 44:1985;247-254.
20. Nieoullon A., Kerkerian L. Presynaptic control of high affinity glutamate uptake in the striatum. Neurosci. Lett. 43:1983;191-196.
21. Nieoullon A., Kerkerian-Le Goff L. Cellular interactions in the striatum involving neuronal systems using "classical neurotransmitters": possible functions and implication. Mov. Disorders. 7:1992;311-325.
22. Pines G., Dandolt N.C., Bjoras M., Zhang Y., Bendahan A., Eide L., Koepsell H., Storm-Mathisen J., Seeberg E., Kanner B.I. Cloning and expression of a rat brain L-glutamate transporter. Nature. 360:1992;464-467.
23. Reine G., Samuel D., Nieoullon A., Kerkerian-Le Goff L. Effects of lesion of the cholinergic basal forebrain nuclei on the activity of glutamatergic and GABAergic systems in the rat frontal cortex and hippocampus. J. Neural Transm. 87:1992;175-192.
24. Robinson M.B., Djali S., Buchalter J.R. Inhibition of glutamate uptake with L-trans-pyrrolidine-2,4-dicarboxylate potentiates glutamate toxicity in primary hippocampal cultures. J. Neurochem. 61:1993;2099-2103.
25. Rothstein J.D., Jin L., Dykes-Hoberg M., Kuncl R.W. Chronic inhibition of glutamate uptake produces a model of slow neurotoxicity. Proc. Natn. Acad. Sci. U.S.A. 90:1992;6591-6595.
26. Rothstein J.D., Martin L.J., Kuncl R.W. Decreased glutamate transport by brain and spinal cord in amyotrophic lateral sclerosis. N. Engl. J. Med. 326:1993;1464-1468.
27. Seamon K.B., Daly J.W. Activation of adenylate cyclase by the diterpene forskolin does not require the guanine nucleotide regulatory protein. J. Biol. Chem. 256:1981;9799-9801.
28. Tian Y., Kapatos G., Granneman J.G., Banon M.J. Dopamine and γ-aminobutyric acid transporters: differential regulation by agents that promote phosphorylation. Neurosci. Lett. 173:1994;143-146.
29. Volterra A., Trotti D., Racagni G. Glutamate uptake is inhibited by arachidonic acid and oxygen radicals via two distinct and additive mechanisms. Molec. Pharmacol. 46:1994;986-992.
30. Zerangue N., Arriza J.L., Amara S.G., Kavanaugh M.P. Differential modulation of human glutamate transporter subtypes by arachidonic acid. J. Biol. Chem. 270:1995;6433-6435.