Efforts to broaden HIV-1-specific immunity by boosting with heterologous peptides or envelope protein and the influence of prior exposure to virus

Journal of Medical Primatology

Volumn 28, Issue 4-5, 1999, Pages 224-232

  Verschoor, Ernst J ^a   Davis, David ^b   Van Gils, Mariëlle ^a   Koopman, Gerrit ^a   Mooij, Petra ^a   Oostermeijer, Herman ^a   Ten Haaft, Peter ^a   Verstrepen, Babs ^a   Rosenwirth, B ^a   Morein, Bror ^c   Barnett, Susan W ^d   Heeney, Jonathan L ^a  

^a BIOMEDICAL PRIMATE RESEARCH CENTRE   (Netherlands)

^b INSTITUTE OF TROPICAL MEDICINE   (Belgium)

^c NATIONAL VETERINARY INSTITUTE   (Sweden)

^d NOVARTIS PHARMA AG   (Switzerland)

Author keywords

AIDS vaccine; Antigenic sin; Broadening immunity; Live attenuated effect; Rhesus macaque

Indexed keywords

EPITOPE; GLYCOPROTEIN GP 120; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; LIVE VACCINE; PEPTIDE FRAGMENT; VIRUS ENVELOPE PROTEIN;

ANIMAL; ANIMAL DISEASE; ARTICLE; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNIZATION; IMMUNOLOGY; MACACA; ORTHOMYXOVIRUS; SIMIAN IMMUNODEFICIENCY VIRUS; VIRUS LOAD;

AIDS VACCINES; ANIMALS; EPITOPES; HIV ENVELOPE PROTEIN GP120; HIV-1; IMMUNIZATION; MACACA MULATTA; ORTHOMYXOVIRIDAE; PEPTIDE FRAGMENTS; SIMIAN IMMUNODEFICIENCY VIRUS; VACCINES, ATTENUATED; VIRAL ENVELOPE PROTEINS; VIRAL LOAD;

EID: 18344398416     PISSN: 00472565     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0684.1999.tb00273.x     Document Type: Article

References (40)

1. ALMOND N, KENT K, CRANAGE M, RUD E, CLARKE B, STOTT EJ: Protection by attenuated simian immunodeficiency virus in macaques against challenge with virus-infected cells (see comments). Lancet 345:1342-1344, 1995.
2. BERGLUND P, QUESADA-ROLANDER M, PUTKONEN P, BIBERFELD G, THORSTENSSON R, LILJESTROM P: Outcome of immunization of cynomolgus monkeys with recombinant Semliki Forest virus encoding human immunodeficiency virus type 1 envelope protein and challenge with a high dose of SHIV-4 virus. AIDS Res Hum Retroviruses 13:1487-1495, 1997.
3. BERMAN PW, MURTHY KK, WRIN T, VENNARI JC, COBB EK, EASTMAN DJ, CHAMPE M, NAKAMURA GR, DAVISON D, POWELL MF, BUSSIERE J, FRANCIS DP, MATTHEWS T, GREGORY TJ, OBIJESKI JF: Protection of MN-rgp120-immunized chimpanzees from heterologous infection with a primary isolate of human immunodeficiency virus type I. J Infect Dis 173:52-59, 1996.
4. BOGERS WM, DUBBES R, TEN HAAFT P, NIPHUIS H, CHENG-MAYER C, STAHL-HENNIG C, HUNSMANN G, KUWATA T, HAYAMI M, JONES S, RANJBAR S, ALMOND N, STOTT J, ROSENWIRTH B, HEENEY JL: Comparison of in vitro and in viro infectivity of different clade B HIV-1 envelope chimeric simian/human immunodeficiency viruses in Macaca mulatta. Virology 236:110-117, 1997.
5. BOGERS WM, NIPHUIS H, TEN HAAFT P, LAMAN JD, KOORNSTRA W, HEENEY JL: Protection from HIV-1 envelope-bearing chimeric simian immunodeficiency virus (SHIV) in rhesus macaques infected with attenuated SIV: Consequences of challenge. AIDS 9:F13-18, 1995.
6. BOYER JD, UGEN KE, WANG B, AGADJANYAN M, GILBERT L, BAGARAZI ML, CHATTERGOON M, FROST P, JAVADIAN A, WILLIAMS WV, REFAELI Y, CICCARELLI RB, MCCALLUS D, CONEY L, WEINER DB: Protection of chimpanzees from high-dose heterologous HIV-1 challenge by DNA vaccination. Nat Med 3:526-532, 1997.
7. BOYER JD, WANG B, UGEN KE, AGADJANYAN M, JAVADIAN A, FROST P, DANG K, CARRANO RA, CICCARELLI R, CONEY L, WILLIAMS WV, WEINER DB: In vivo protective anti-HIV immune responses in non-human primates through DNA immunization. J Med Primatol 25:242-250, 1996.
8. BRUCK C, THIRIART C, FABRY L, FRANCOTTE M, PALA P, VAN OPSTAL O, CULP J, ROSENBERG M, DE WILDE M, HEIDT P, HEENEY JL: HIV-1 envelope-elicited neutralizing antibody titres correlate with protection and virus load in chimpanzees. Vaccine 12:1141-1148, 1994.
9. CHENG-MAYER C, SHIODA T, LEVY JA: Host range, replicative, and cytopathic properties of human immunodeficiency virus type 1 are determined by very few amino acid changes in tat and gp120. J Virol 65:6931-6941, 1991.
10. CRANAGE MP, WHATMORE AM, SHARPE SA, COOK N, POLYANSKAYA N, LEECH S, SMITH JD, RUD EW, DENNIS MJ, HALL GA: Macaques infected with live attenuated SIVmac are protected against superinfection via the rectal mucosa. Virology 229:143-154, 1997.
11. DANIEL MD, KIRCHHOFF F, CZAJAK SC, SEHGAL PK, DESROSIERS RC: Protective effects of a live attenuated SIV vaccine with a deletion in the nef gene (see comments). Science 258:1938-1941, 1992.
12. DAVIS D, MOREIN B, ÅKERBLOM L, VAN GILS ME, BOGERS W, TEEUWSEN V, HEENEY JL: A recombinant prime, peptide boost vaccination strategy can focus the immune response on to more than one epitope even though these may not be immunodominant in the complex immunogen. Vaccine 15:1661-1669, 1997.
13. DUNN CS, HURTREL B, BEYER C, GLOECKLER L, LEDGER TN, MOOG C, KIENY MP, MEHTALI M, SCHMITT D, GUT JP, KIRN A, AUBERTIN AM: Protection of SIVmac-infectcd macaque monkeys against superinfection by a simian immunodeficiency virus expressing envelope glycoproteins of HIV type 1. AIDS Res Hum Retroviruses 13:913-922, 1997.
14. FAZEKAS DE ST G, WEBSTER RG: Disquisitions of Original Antigenic Sin. I. Evidence in man. J Exp Med 124:331-345, 1966.
15. FAZEKAS DE ST G, WEBSTER RG: Disquisitions on Original Antigenic Sin. II. Proof in lower creatures. J Exp Med 124:347-361, 1966.
16. GOODENOW M, HUET T, SAURIN W, KWOK S, SNINSKY J, WAIN-HOBSON S: HIV-1 isolates are rapidly evolving quasispecies: Evidence for viral mixtures and preferred nucleotide substitutions. J Acquir Immune Defic Syndr 2:344-352, 1989.
17. HEENEY JL, TEEUWSEN VJ, VAN GILS M, BOGERS WM, DE GIULI MORGHEN C, RADAELLI A, BARNETT S, MOREIN B, AKERBLOM L, WANG Y, LEHNER T, DAVIS D: Beta-chemokines and neutralizing antibody titers correlate with sterilizing immunity generated in HIV-1 vaccinated macaques. Proc Natl Acad Sci USA 95:10803-10808, 1998.
18. HEENEY JL, VAN ELS C, DE VRIES P, TEN HAAFT P, OTTING N, KOORNSTRA W, BOES J, DUBBES R, NIPHUIS H, DINGS M et al.: Major histocompatibility complex class I-associated vaccine protection from simian immunodeficiency virus-infected peripheral blood cells. J Exp Med 180:769-774, 1994.
19. HEENEY JL, VAN GILS ME, VAN DER MEIDE P, DE GIULI MORGHEN C, GHIONI C, GIMELLI M, RADDELLI A, DAVIS D, AKERBLOM L, MOREIN B: The role of type-1 and type-2 T-helper immune responses in HIV-1 vaccine protection. J Med Primatol 27:50-58, 1998.
20. HOLLAND J, SPINDLER K, HORODYSKI F, GRABAU E, NICHOL S, VANDEPOL S: Rapid evolution of RNA genomes. Science 215:1577-1585, 1982.
21. KLENERMAN P, ZINKERNAGEL RM: Original antigenic sin impairs cytotoxic T lymphocyte responses to viruses bearing variant epitopes (see comments). Nature 394:482-485, 1998.
22. LEHNER T, WANG Y, CRANAGE M, BERGMEIER LA, MITCHELL E, TAO L, HALL G, DENNIS M, COOK N, BROOKES R, KLAVINSKIS L, JONES I, DOYLE C, WARD R: Protective mucosal immunity elicited by targeted iliac lymph node immunization with a subunit SIV envelope and core vaccine in macaques (see comments). Nat Med 2:767-775, 1996.
23. LETVIN NL, MONTEFIORI DC, YASUTOMI Y, PERRY HC, DAVIES ME, LEKUTIS C, ALROY M, FREED DC, LORD CI, HANDT LK, LIU MA, SHIVER JW: Potent, protective anti-HIV immune responses generated by bimodal HIV envelope DNA plus protein vaccination. Proc Natl Acad Sci USA 94:9378-9383, 1997.
24. LOCHER CP, BLACKBOURN DJ, BARNETT SW, MURTHY KK, COBB EK, ROUSE S, GRECO G, REYES-TERAN G, BRASKY KM, CAREY KD, LEVY JA: Superinfection with human immunodeficiency virus type 2 can reactivate virus production in baboons but is contained by a CD8 T cell antiviral response. J Infect Dis 176:948-959, 1997.
25. LU Y, SALVATO MS, PAUZA CD, LI J, SODROSKI J, MANSON K, WYAND M, LETVIN N, JENKINS S, TOUZJIAN N, CHUTKOWSKI C, KUSHNER N, LEFAILE M, PAYNE LG, ROBERTS B: Utility of SHIV for testing HIV-1 vaccine candidates in macaques. J Acquir Immune Defic Syndr Hum Retrovirol 12:99-106, 1996.
26. LUCIW PA, PRATT-LOWE E, SHAW KE, LEVY JA, CHENG-MAYER C: Persistent infection of rhesus macaques with T-cell-line-tropic and macrophage-tropic clones of simian/human immunodeficiency viruses (SHIV). Proc Natl Acad Sci USA 92:7490-7494, 1995.
27. MOOIJ P, VAN DER KOLK M, BOGERS WM, TEN HAAFT PJ, VAN DER MEIDE P, ALMOND N, STOTT J, DESCHAMPS M, LABBE D, MOMIN P, VOSS G, VON HOEGEN P, BRUCK C, HEENEY JL: A clinically relevant HIV-1 subunit vaccine protects rhesus macaques from in vivo passaged simian-human immunodeficiency virus infection. Aids 12:FI5-22, 1998.
28. NARA PL, SMIT L, DUNLOP N, HATCH W, MERGES M, WATERS D, KELLIHER J, GALLO RC, FISCHINGER PJ, GOUDSMIT J: Emergence of viruses resistant to neutralization by V3-specific antibodies in experimental human immunodeficiency virus type 1 IIIB infection of chimpanzees. J Virol 64:3779-3791, 1990.
29. ROBERT-GUROFF M, KAUR H, PATTERSON LJ, LENO M, CONLEY AJ, MCKENNA PM, MARKHAM PD, RICHARDSON E, ALDRICH K, ARORA K, MURTY L, CARTER L, ZOLLA-PAZNER S, SINANGIL F: Vaccine protection against a heterologous, non-syncytium-inducing, primary human immunodeficiency virus. J Virol 72:10275-10280, 1998.
30. SHIBATA R, KAWAMURA M, SAKAI H, HAYAMI M, ISHIMOTO A, ADACHI A: Generation of a chimeric human and simian immunodeficiency virus infectious to monkey peripheral blood mononuclear cells. J Virol 65:3514-3520, 1991.
31. SHIBATA R, SEIMON C, CHO MW, ARTHUR LO, NIGIDA SJR, MATTHEWS T, SAWYER LA, SCHULTZ A, MURTHY KK, ISRAEL Z, JAVADIAN A, FROST P, KENNEDY RC, LANE HC, MARTIN MA: Resistance of previously infected chimpanzees to successive challenges with a heterologous intraclade B strain of human immunodeficiency virus type 1. J Virol 70:4361-4369, 1996.
32. SJOLANDER A, VAN'S LAND B, LOVGREN BENGTSSON K: Iscoms containing purified Quillaja saponins upregulate both Th1-like and Th2-like immune responses. Cell Immunol 177:6976, 1997.
33. STEINUAUER DA, HOLLAND JJ: Rapid evolution of RNA viruses. Annu Rev Microbiol 41:409-433, 1987.
34. STEPHENS EB, JOAG SV, ATKINSON B, SAHNI M, LI Z, FORESMAN L, ADANY I, NARAYAN O: Infected macaques that controlled replication of SIVmac or nonpathogenic SHIV developed sterilizing resistance against pathogenic SHIV(KU-1). Virology 234:328-339, 1997.
35. STOTT EJ, ALMOND N, KENT K, WALKER B, HULL R, ROSE J, SILVERA P, SANGSTER R, CORCORAN T, LINES J, SILVERA K, LUCIW P, MURPHY-CORB M, MOMIN P, BRUCK C: Evaluation of a candidate human immunodefi-ciency virus type 1 (HIV-1) vaccine in macaques: effect of vaccination with HIV-1 gp120 on subsequent challenge with heterologous simian immunodeficiency virus-HIV-1 chimeric virus. J Gen Virol 79:423-432, 1998.
36. TEN HAAFT P, VERSTREPEN B, UBERLA K, ROSENWIRTH B, HEENEY J: A pathogenic threshold of virus load defined in simian immunodeficiency virus- or simian-human immunodeficiency virus-infected macaques. J Virol 72:10281-10285, 1998.
37. TITTI F, SERNICOLA L, GERACI A, PANZINI G, DI FABIO S, BELLI R, MONARDO F, BORSETTI A, MAGGIORELLA MT, KOANGA-MOGTOMO M, CORRIAS F, ZAMARCHI R, AMADORI A, CHIECOBIANCHI L, VERANI P: Live attenuated simian immunodeficiency virus prevents superinfection by cloned SIVmac251 in cvnomolgus monkeys. J Gen Virol 78:2529-2539, 1997.
38. TRAQUINA P, MORANDI M, CONTORNI M, VAN NEST G: MF59 adjuvant enhances the antibody response to recombinant hepatitis B surface antigen vaccine in primates. J Infect Dis 174:1168-1175, 1996.
39. VERSCHOOR EJ, MOOIJ P, OOSTERMEIJER H, VAN DER KOLK M, TEN HAAFT P, VERSTREPEN B, SUN Y, MOREIN B, AKERBLOM L, FULLER DH, BARNETT SW, HEENEY JL: Comparison of immunity generated by nucleic acid, MF59 and ISCOM-formulated HIV-1 gp120 vaccines in rhesus macaques: Evidence for viral clearance. J Virol 73:3292-3300, 1999.
40. WAGNER R, TEEUWSEN VJ, DEML L, NOTKA F, HAAKSMA AG, JHAGJHOORSINGH SS, NIPHUIS H, WOLF H, HEENEY JL: Cytotoxic T cells and neutralizing antibod-ies induced in rhesus monkeys by virus-like particle HIV vaccines in the absence of protection from SHIV infection. Virology 245:65-74, 1998.