Cytogenetic and molecular analysis of early stage renal cell carcinomas in a family with a translocation (2;3)(q35;q21)

Cancer Genetics and Cytogenetics

Volumn 134, Issue 1, 2002, Pages 6-12

  Bodmer, Danielle ^a   Eleveld, Marc ^a   Ligtenberg, Marjolijn ^a   Weterman, Marian ^a   Van der Meijden, Adrian ^b   Koolen, Marianne ^b   Smits, Arie ^a   Smeets, Dominique ^a   Van Kessel, Ad Geurts ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b JEROEN BOSCH HOSPITAL   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CANCER GROWTH; CANCER STAGING; CHROMOSOME 3; CHROMOSOME LOSS; CHROMOSOME TRANSLOCATION; CONTROLLED STUDY; FAMILIAL CANCER; FAMILY STUDY; GENE MUTATION; HETEROZYGOSITY LOSS; HISTOLOGY; HUMAN; HUMAN TISSUE; KARYOTYPE; KIDNEY CARCINOMA; PEDIGREE; PRIORITY JOURNAL; SOMATIC MUTATION; TUMOR BIOPSY; VON HIPPEL LINDAU DISEASE;

BASE SEQUENCE; CARCINOMA, RENAL CELL; CHROMOSOMES, HUMAN, PAIR 2; CHROMOSOMES, HUMAN, PAIR 3; CYTOGENETIC ANALYSIS; DNA MUTATIONAL ANALYSIS; DNA, NEOPLASM; FAMILY HEALTH; FEMALE; HUMANS; KARYOTYPING; KIDNEY NEOPLASMS; LIGASES; LOSS OF HETEROZYGOSITY; MALE; MICROSATELLITE REPEATS; NEOPLASM STAGING; PEDIGREE; POINT MUTATION; TRANSLOCATION, GENETIC; TUMOR SUPPRESSOR PROTEINS; UBIQUITIN-PROTEIN LIGASES; VON HIPPEL-LINDAU TUMOR SUPPRESSOR PROTEIN;

EID: 18344395129     PISSN: 01654608     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-4608(01)00585-4     Document Type: Article

References (29)

1. Renal-cell carcinoma
2. Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas
3. Inherited carcinomas of the kidney
4. Hereditary renal cell carcinoma associated with chromosomal translocation
5. Loss of der(3) in renal carcinoma cells of a patient with constitutional t(3;12)
6. Tissue-specific expression of a constitutional 3;6 translocation: Development of multiple bilateral renal-cell carcinomas
7. A familial case of renal cell carcinoma and a t(2;3) chromosome translocation
8. Renal cell cancer: Chromosome 3 translocations as risk factors
9. Familial renal cancer (CRCC) associated with a constitutional reciprocal translocation t(2;3)(q33;q21)
10. Association of a novel constitutional translocation t(1q;3q) with familial renal cell carcinoma
11. Familial non-VHL non-papillary clear-cell renal cancer
12. Reviews on chromosome studies in urological tumours
13. Cytogenetic classification of renal cell cancer
14. Cytogenetics of renal cell carcinomas associated with von Hippel-Lindau disease
15. Mutations of the VHL tumour suppressor gene mutations in renal carcinoma tumorigenesis
16. Molecular cytogenetics of renal cell tumours
17. Involvement of multiple loci on chromosome 3 in renal cell cancer development
18. Definition of a tumour suppressor locus within human
19. A tumor suppressor locus within 3p14-12 mediates rapid cell death of renal cell carcinoma in vivo
20. Deletion of two separate regions on chromosome 3 in breast cancer
21. Silincing of the VHL tumour suppressor gene by DNA methylation in renal carcinoma
22. Inactivation of the von Hippel-Lindau (VHL) tumour suppressor gene and allelic losses at chromosome arm 3p in primary renal cell carcinoma: Evidence for a VHL-independent pathway in clear cell renal tumourigenesis
23. Combined LOH/CGH analyses proves the existence of interstitial 3p deletions in renal cell carcinoma
24. An alternative route for multi-step tumorigenesis in a novel case of hereditary renal cell cancer and a t(2;3)(q35;q21) chromosome translocation
25. Clinical and genetic studies of renal cell carcinomas in a family with a constitutional chromosome 3;8 translocation: Genetics of familial renal carcinoma
26. Mechanisms of tumorigenesis of renal carcinomas associated with the constitutional chromosome 3;8 translocation
27. Molecular analysis of a familial case of renal cell cancer and a t(3;6)(q12;q15)
28. Sensitivity to genotoxic effects of bleomycin in humans: Possible relationship to environmental carcinogenesis