Biphenylsulfonamide endothelin receptor antagonists. Part 3: Structure-activity relationship of 4′-heterocyclic biphenylsulfonamides

Bioorganic and Medicinal Chemistry Letters

Volumn 12, Issue 4, 2002, Pages 517-520

  Murugesan, Natesan ^a   Gu, Zhengxiang ^a   Stein, Philip D ^a   Spergel, Steven ^a   Bisaha, Sharon ^a   Liu, Eddie C K ^a   Zhang, Rongan ^a   Webb, Maria L ^a   Moreland, Suzanne ^a   Barrish, Joel C ^a  

^a BRISTOL MYERS SQUIBB PHARMACEUTICAL RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BMS 193884; ENDOTHELIN A RECEPTOR; ENDOTHELIN A RECEPTOR ANTAGONIST; ENDOTHELIN B RECEPTOR; FUNCTIONAL GROUP; HETEROCYCLIC COMPOUND; PYRIMIDINE DERIVATIVE; SULFONAMIDE; BIPHENYL DERIVATIVE; ENDOTHELIN RECEPTOR;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING ASSAY; CHO CELL; CONTROLLED STUDY; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; NONHUMAN; STRUCTURE ACTIVITY RELATION; ANIMAL; CHEMISTRY; DRUG ANTAGONISM; GENETIC TRANSFECTION; GENETICS; HAMSTER; HUMAN; METABOLISM; PROTEIN BINDING; SYNTHESIS;

ANIMALS; BIPHENYL COMPOUNDS; CHO CELLS; CRICETINAE; HUMANS; PROTEIN BINDING; RECEPTOR, ENDOTHELIN A; RECEPTORS, ENDOTHELIN; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONAMIDES; TRANSFECTION;

EID: 18244406845     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(01)00791-0     Document Type: Article

References (13)