-
1
-
-
0027530041
-
Blood levels of organochlorine residues and risk of breast cancer
-
Wolff, M.S., Toniolo, P.G., Lee, E.W., Rivera, M. and Dubin, N. (1993) "Blood levels of organochlorine residues and risk of breast cancer", J. Natl Cancer Inst. 85, 648-652.
-
(1993)
J. Natl Cancer Inst.
, vol.85
, pp. 648-652
-
-
Wolff, M.S.1
Toniolo, P.G.2
Lee, E.W.3
Rivera, M.4
Dubin, N.5
-
2
-
-
0003059076
-
Swimming in a sea of estrogens, chemical hormone disrupters
-
Dibb, S. (1995) "Swimming in a sea of estrogens, chemical hormone disrupters", The Ecologist 25, 27-31.
-
(1995)
The Ecologist
, vol.25
, pp. 27-31
-
-
Dibb, S.1
-
3
-
-
0000649537
-
Environmental estrogens
-
McLachlan, J.A. and Arnold, S.F. (1996) "Environmental estrogens", Am. Sci. 84, 452-461.
-
(1996)
Am. Sci.
, vol.84
, pp. 452-461
-
-
McLachlan, J.A.1
Arnold, S.F.2
-
4
-
-
0031056329
-
In vitro bioassays for assessing estrogenic substances
-
Zacharewski, T. (1997) "In vitro bioassays for assessing estrogenic substances", Environ. Sci. Technol. 31, 613-623.
-
(1997)
Environ. Sci. Technol.
, vol.31
, pp. 613-623
-
-
Zacharewski, T.1
-
5
-
-
0006809325
-
Effects of in vivo administration of 2,3,7,8-TCDD on receptor binding of epidermal growth factor in the hepatic plasma membrane of rat, guinea pig, mouse, and hamster
-
Madhukar, B.V., Brewster, D.W. and Matsumura, F. (1984) "Effects of in vivo administration of 2,3,7,8-TCDD on receptor binding of epidermal growth factor in the hepatic plasma membrane of rat, guinea pig, mouse, and hamster", Proc. Natl Acad. Sci. 81, 7407-7411.
-
(1984)
Proc. Natl Acad. Sci.
, vol.81
, pp. 7407-7411
-
-
Madhukar, B.V.1
Brewster, D.W.2
Matsumura, F.3
-
6
-
-
0029583261
-
Receptor-mediated toxicity
-
Gustaffson, J.A. (1995) "Receptor-mediated toxicity", Toxicol. Lett. 135, 465-470.
-
(1995)
Toxicol. Lett.
, vol.135
, pp. 465-470
-
-
Gustaffson, J.A.1
-
7
-
-
0028006520
-
The Ah receptor: Mediator of the toxicity of 2,3,7,8-tetrachlorodibenzo- p-dioxin (TCDD) and related compounds
-
Okey, A.B., Riddick, D.S. and Harper, P.A. (1994) "The Ah receptor: mediator of the toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and related compounds", Toxicol. Lett. 70, 1-22.
-
(1994)
Toxicol. Lett.
, vol.70
, pp. 1-22
-
-
Okey, A.B.1
Riddick, D.S.2
Harper, P.A.3
-
8
-
-
0006057511
-
Cellular and molecular biology of Aryl hydrocarbon (Ah) receptor-mediated gene expression
-
Degen, D.H., Seiler, J.P. and Bentley, P., eds, Springer, Berlin
-
Safe, S. and Krishnan, K. (1995) "Cellular and molecular biology of Aryl hydrocarbon (Ah) receptor-mediated gene expression", In: Degen, D.H., Seiler, J.P. and Bentley, P., eds, Archives of Toxicology, Supplement 17 (Springer, Berlin) Suppl. 17, pp 116-124.
-
(1995)
Archives of Toxicology, Supplement 17
, Issue.17 SUPPL.
, pp. 116-124
-
-
Safe, S.1
Krishnan, K.2
-
9
-
-
0027729369
-
Detergent compounds in sewage effluents are weakly oestrogenic to fish: An in vitro study using rainbow trout Onchorhyncus mykiss hepatocytes
-
Jobling, S. and Sumpter, J.P. (1993) "Detergent compounds in sewage effluents are weakly oestrogenic to fish: an in vitro study using rainbow trout Onchorhyncus mykiss hepatocytes", Aquat. Toxicol. 27, 361-372.
-
(1993)
Aquat. Toxicol.
, vol.27
, pp. 361-372
-
-
Jobling, S.1
Sumpter, J.P.2
-
10
-
-
0028233813
-
Environmental persistent alkylphenolic compounds are estrogenic
-
Hoare, S.A., Jobling, S., Parker, M.G., Sumpter, J.P. and White, R. (1994) "Environmental persistent alkylphenolic compounds are estrogenic", Endocrinology 135, 175-182.
-
(1994)
Endocrinology
, vol.135
, pp. 175-182
-
-
Hoare, S.A.1
Jobling, S.2
Parker, M.G.3
Sumpter, J.P.4
White, R.5
-
11
-
-
0028849731
-
Organization versus activation: The role of endocrine disrupting contaminants EDCs during embryonic development in wildlife
-
Guillette, L.J., Crain, D.A., Rooney, A.A. and Pickford, D.B. (1995) "Organization versus activation: the role of endocrine disrupting contaminants EDCs during embryonic development in wildlife", Environ. Health Perspect. 103(Suppl. 7), 157-164.
-
(1995)
Environ. Health Perspect.
, vol.103
, Issue.7 SUPPL.
, pp. 157-164
-
-
Guillette, L.J.1
Crain, D.A.2
Rooney, A.A.3
Pickford, D.B.4
-
12
-
-
0028832564
-
Environmental estrogens: Health implications for humans and wildlife
-
Colborn, T. (1995) "Environmental estrogens: health implications for humans and wildlife", Environ. Health Perspect. 103(Suppl. 7), 135-136.
-
(1995)
Environ. Health Perspect.
, vol.103
, Issue.7 SUPPL.
, pp. 135-136
-
-
Colborn, T.1
-
13
-
-
0028857865
-
Estrogens in unexpected places: Possible implications for researchers and consumers
-
Feldman, D. and Krishnan, A. (1995) "Estrogens in unexpected places: possible implications for researchers and consumers", Environ. Health Perspect. 103(Suppl. 7), 129-133.
-
(1995)
Environ. Health Perspect.
, vol.103
, Issue.7 SUPPL.
, pp. 129-133
-
-
Feldman, D.1
Krishnan, A.2
-
14
-
-
0000848054
-
Synthetic estrogens and the relation between their structure and their activity
-
Solmssen, U.V. (1945) "Synthetic estrogens and the relation between their structure and their activity", Chem. Rev. 37, 481-598.
-
(1945)
Chem. Rev.
, vol.37
, pp. 481-598
-
-
Solmssen, U.V.1
-
15
-
-
0023554425
-
Estrogen receptor stereochemistry: Receptor binding and hormonal responses
-
Korach, K.S., Levy, L.A. and Sarver, P.J. (1987) "Estrogen receptor stereochemistry: receptor binding and hormonal responses", J. Steroid Biochem. 27, 281-290.
-
(1987)
J. Steroid Biochem.
, vol.27
, pp. 281-290
-
-
Korach, K.S.1
Levy, L.A.2
Sarver, P.J.3
-
16
-
-
0027021245
-
An 'in culture' bioassay to assess the estrogenicity of xenobiotics E-screen
-
Colburn, T. and Clement, C., eds, Princeton Scientific Publishing, Princeton
-
Soto, A.M., Lin, T.M., Justicia, H., Silvia, R.M. and Sonnennschein, C. (1992) "An 'in culture' bioassay to assess the estrogenicity of xenobiotics E-screen", In: Colburn, T. and Clement, C., eds, Chemically Induced Alterations in Sexual and Functional Development: The Wildliferhuman Connection (Princeton Scientific Publishing, Princeton), pp 295-309.
-
(1992)
Chemically Induced Alterations in Sexual and Functional Development: the Wildliferhuman Connection
, pp. 295-309
-
-
Soto, A.M.1
Lin, T.M.2
Justicia, H.3
Silvia, R.M.4
Sonnennschein, C.5
-
17
-
-
18744421821
-
Wood-derived estrogens: Studies in vitro with breast cancer cell lines and in vivo in trout
-
Mellanen, P., Petanen, T. and Lehtimaki, J. (1996) "Wood-derived estrogens: studies in vitro with breast cancer cell lines and in vivo in trout", Toxicol. Appl. Pharmacol. 136, 381-388.
-
(1996)
Toxicol. Appl. Pharmacol.
, vol.136
, pp. 381-388
-
-
Mellanen, P.1
Petanen, T.2
Lehtimaki, J.3
-
18
-
-
0023751431
-
Comparative molecular field analysis (CoMFA). 1. Effect of shape on binding of steroids to carrier proteins
-
Cramer, R.D., III, Patterson, D.E. and Bunce, J.D. (1988) "Comparative molecular field analysis (CoMFA). 1. Effect of shape on binding of steroids to carrier proteins", J. Am. Chem. Soc. 110, 5959-5967.
-
(1988)
J. Am. Chem. Soc.
, vol.110
, pp. 5959-5967
-
-
Cramer III, R.D.1
Patterson, D.E.2
Bunce, J.D.3
-
19
-
-
0027944195
-
Molecular similarity indices in a comparative analysis (CoMSIA) of drug molecules to correlate and predict their biological potency
-
Klebe, G., Abraham, U. and Mietzner, T. (1994) "Molecular similarity indices in a comparative analysis (CoMSIA) of drug molecules to correlate and predict their biological potency", J. Med. Chem. 37, 4130-4146.
-
(1994)
J. Med. Chem.
, vol.37
, pp. 4130-4146
-
-
Klebe, G.1
Abraham, U.2
Mietzner, T.3
-
20
-
-
0032474873
-
Three-dimensional quantitative similarity-activity relationships (3D QsiAR) from SEAL similarity matrices
-
Kubinyi, H., Hamprecht, F.A. and Mietzner, T. (1998) "Three- dimensional quantitative similarity-activity relationships (3D QsiAR) from SEAL similarity matrices", J. Med. Chem. 41, 2553-2564.
-
(1998)
J. Med. Chem.
, vol.41
, pp. 2553-2564
-
-
Kubinyi, H.1
Hamprecht, F.A.2
Mietzner, T.3
-
21
-
-
0027310371
-
Generating Optimal Linear PLS Estimations (GOLPE): An advanced chemometric tool for handling 3D-QSAR problems
-
Baroni, M., Costantino, G., Cruciani, G., Riganelli, D., Valigi, R. and Clementi, S. (1993) "Generating Optimal Linear PLS Estimations (GOLPE): an advanced chemometric tool for handling 3D-QSAR problems", Quant. Struct. - Act. Relat. 12, 9-20.
-
(1993)
Quant. Struct. - Act. Relat.
, vol.12
, pp. 9-20
-
-
Baroni, M.1
Costantino, G.2
Cruciani, G.3
Riganelli, D.4
Valigi, R.5
Clementi, S.6
-
22
-
-
0034676316
-
Multiple conformation and protonation-state representation in 4D-QSAR: The neurokinin-1 receptor system
-
Vedani, A., Briem, H., Dobler, M., Dollinger, K. and McMasters, D.R. (2000) "Multiple conformation and protonation-state representation in 4D-QSAR: the neurokinin-1 receptor system", J. Med. Chem. 43, 4416-4427.
-
(2000)
J. Med. Chem.
, vol.43
, pp. 4416-4427
-
-
Vedani, A.1
Briem, H.2
Dobler, M.3
Dollinger, K.4
McMasters, D.R.5
-
23
-
-
0037161586
-
5D-QSAR: The key for simulating induced fit?
-
Vedani, A. and Dobler, M. (2002) "5D-QSAR: the key for simulating induced fit?", J. Med. Chem. 45, 2139-2149.
-
(2002)
J. Med. Chem.
, vol.45
, pp. 2139-2149
-
-
Vedani, A.1
Dobler, M.2
-
24
-
-
0034010498
-
Multi-conformational ligand representation in 4D-QSAR: Reducing the bias associated with ligand alignment
-
Vedani, A., McMasters, D.R. and Dobler, M. (2000) "Multi- conformational ligand representation in 4D-QSAR: reducing the bias associated with ligand alignment", Quant. Struct. - Act. Relat. 19, 149-161.
-
(2000)
Quant. Struct. - Act. Relat.
, vol.19
, pp. 149-161
-
-
Vedani, A.1
McMasters, D.R.2
Dobler, M.3
-
25
-
-
85195079920
-
Dual-shell representation in receptor modeling: Quantitative prediction of ligand-protein binding affinities
-
In press
-
Lill, M.A., Dobler, M. and Vedani, A., "Dual-shell representation in receptor modeling: quantitative prediction of ligand-protein binding affinities", J. Med. Chem., In press.
-
J. Med. Chem.
-
-
Lill, M.A.1
Dobler, M.2
Vedani, A.3
-
26
-
-
0038749409
-
From crystal structures and their analysis to the in silico prediction of toxic phenomena
-
Dobler, M., Lill, M.A. and Vedani, A. (2003) "From crystal structures and their analysis to the in silico prediction of toxic phenomena", Helv. Chim. Acta 86, 1554-1568.
-
(2003)
Helv. Chim. Acta
, vol.86
, pp. 1554-1568
-
-
Dobler, M.1
Lill, M.A.2
Vedani, A.3
-
27
-
-
0036794599
-
Multi-dimensional QSAR: Moving from three- To five-dimensional concepts
-
Vedani, A. and Dobler, M. (2002) "Multi-dimensional QSAR: moving from three- to five-dimensional concepts", Quant. Struct. - Act. Relat. 21, 382-390.
-
(2002)
Quant. Struct. - Act. Relat.
, vol.21
, pp. 382-390
-
-
Vedani, A.1
Dobler, M.2
-
28
-
-
9644258919
-
The cost of conformational order: Entropy changes in molecular associations"
-
Searle, M.S. and Williams, D.H. (1992) "The cost of conformational order: entropy changes in molecular associations", J. Am. Chem. Soc. 114, 10690-10697.
-
(1992)
J. Am. Chem. Soc.
, vol.114
, pp. 10690-10697
-
-
Searle, M.S.1
Williams, D.H.2
-
29
-
-
0022865373
-
Future paths for integer programming and links to artificial intelligence
-
Glover, F. (1986) "Future paths for integer programming and links to artificial intelligence", Comput. Oper. Res. 5, 533-549.
-
(1986)
Comput. Oper. Res.
, vol.5
, pp. 533-549
-
-
Glover, F.1
-
30
-
-
0024997614
-
Polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs) and related compounds: Environmental and mechanistic considerations which support the development of toxic equivalency factors (TEFs)
-
Safe, S. (1990) "Polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs) and related compounds: environmental and mechanistic considerations which support the development of toxic equivalency factors (TEFs)", CRC Crit. Rev. Toxicol. 21, 51-88.
-
(1990)
CRC Crit. Rev. Toxicol.
, vol.21
, pp. 51-88
-
-
Safe, S.1
-
31
-
-
0033954256
-
The Protein Data Bank
-
www.rcsb.org, Berman, H.M., Westbrook, J., Feng, Z., Gilliland, G., Bhat, T.N., Weissig, H., Shindyalov, I.N. and Bourne, P.E. (2000) "The Protein Data Bank", Nucleic Acids Res. 28, 235-242.
-
(2000)
Nucleic Acids Res.
, vol.28
, pp. 235-242
-
-
Berman, H.M.1
Westbrook, J.2
Feng, Z.3
Gilliland, G.4
Bhat, T.N.5
Weissig, H.6
Shindyalov, I.N.7
Bourne, P.E.8
-
33
-
-
0034020453
-
The estrogen receptor relative binding affinities of 188 natural and xenochemicals: Structural diversity of ligands
-
Blair, R.M., Fang, H., Branham, W.S., Hass, B.S., Dial, S.L., Moland, C.L., Tong, W., Shi, L., Perkins, R. and Sheehan, D.M. (2000) "The estrogen receptor relative binding affinities of 188 natural and xenochemicals: structural diversity of ligands", Toxicol. Sci. 54, 138-153.
-
(2000)
Toxicol. Sci.
, vol.54
, pp. 138-153
-
-
Blair, R.M.1
Fang, H.2
Branham, W.S.3
Hass, B.S.4
Dial, S.L.5
Moland, C.L.6
Tong, W.7
Shi, L.8
Perkins, R.9
Sheehan, D.M.10
-
34
-
-
0032446607
-
The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen
-
Shiau, A.K., Barstad, D., Loria, P.M., Cheng, L., Kushner, P.J., Agard, D.A. and Greene, G.L. (1998) "The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen", Cell 95, 927-937.
-
(1998)
Cell
, vol.95
, pp. 927-937
-
-
Shiau, A.K.1
Barstad, D.2
Loria, P.M.3
Cheng, L.4
Kushner, P.J.5
Agard, D.A.6
Greene, G.L.7
-
35
-
-
85195101650
-
-
pdb-code: IERR
-
pdb-code: IERR.
-
-
-
-
36
-
-
10744231103
-
Study of 202 natural, synthetic, and environmental chemicals for binding to the androgen receptor
-
Fang, H., Tong, W., Branham, W.S., Moland, C.L., Dial, S.L., Hong, H., Xie, Q., Perkins, R., Owens, W. and Sheehan, D.M. (2003) "Study of 202 natural, synthetic, and environmental chemicals for binding to the androgen receptor", Chem. Res. Toxicol. 16, 1338-1358.
-
(2003)
Chem. Res. Toxicol.
, vol.16
, pp. 1338-1358
-
-
Fang, H.1
Tong, W.2
Branham, W.S.3
Moland, C.L.4
Dial, S.L.5
Hong, H.6
Xie, Q.7
Perkins, R.8
Owens, W.9
Sheehan, D.M.10
-
37
-
-
0035942197
-
Crystallographic structures of the ligand-binding domains of the androgen receptor and its T877A mutant complexed with the natural agonist dihydrotestosterone
-
Sack, J.S., Kish, K.F., Wang, C., Attar, R.M., Kiefer, S.E., An, Y., Wu, G.Y., Scheffler, J.E., Salvati, M.E., Krystek, S.R., Jr., Weinmann, R. and Einspahr, H.M. (2001) "Crystallographic structures of the ligand-binding domains of the androgen receptor and its T877A mutant complexed with the natural agonist dihydrotestosterone", Proc. Natl Acad. Sci. 98, 4904-4909.
-
(2001)
Proc. Natl Acad. Sci.
, vol.98
, pp. 4904-4909
-
-
Sack, J.S.1
Kish, K.F.2
Wang, C.3
Attar, R.M.4
Kiefer, S.E.5
An, Y.6
Wu, G.Y.7
Scheffler, J.E.8
Salvati, M.E.9
Krystek Jr., S.R.10
Weinmann, R.11
Einspahr, H.M.12
-
38
-
-
0025158237
-
A new force field for modeling metalloproteins
-
Vedani, A. and Huhta, D.W. (1990) "A new force field for modeling metalloproteins", J. Am. Chem. Soc. 112, 4759-4767
-
(1990)
J. Am. Chem. Soc.
, vol.112
, pp. 4759-4767
-
-
Vedani, A.1
Huhta, D.W.2
|