Immunodetection and clinico-pathological correlates of two tumour growth regulators in laryngeal carcinoma

Histology and Histopathology

Volumn 17, Issue 1, 2002, Pages 131-138

  Lazaris, Andreas Ch ^a   Rigopoulou, A ^a   Tseleni Balafouta, S ^a   Kavantzas, N ^a   Thimara, I ^a   Zorzos, H S ^a   Eutychiadis, C A ^a   Petraki, K ^a   Kandiloros, D ^a   Davaris, P ^a  

^a UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

Author keywords

Immunohistochemistry; Ki67; Larynx; Squamous cell carcinoma; TRF1

Indexed keywords

KI 67 ANTIGEN; PEROXIDASE; POLYCLONAL ANTIBODY; TELOMERASE; TELOMERIC REPEAT BINDING FACTOR 1; UNCLASSIFIED DRUG;

ADULT; AGE; ARTICLE; CANCER CELL; CANCER INVASION; CANCER RECURRENCE; CANCER SIZE; CANCER SURVIVAL; CELL IMMORTALIZATION; CELL PROLIFERATION; CLINICAL FEATURE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; FEMALE; HISTOPATHOLOGY; HUMAN; IMMUNODETECTION; IMMUNOPEROXIDASE STAINING; LARYNGECTOMY; LARYNX CARCINOMA; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; MORPHOMETRICS; MULTIVARIATE ANALYSIS; PREDICTION; PROGNOSIS; PROTEIN EXPRESSION; SQUAMOUS CELL CARCINOMA; STATISTICAL ANALYSIS; TELOMERE; TELOMERIC REPEAT AMPLIFICATION PROTOCOL; TUMOR GROWTH;

ADOLESCENT; ADULT; AGED; CARCINOMA, SQUAMOUS CELL; CHILD; DNA-BINDING PROTEINS; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; KI-67 ANTIGEN; LARYNGEAL NEOPLASMS; LOGISTIC MODELS; MALE; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; PARAFFIN EMBEDDING; PREDICTIVE VALUE OF TESTS; PROGNOSIS; SURVIVAL; TELOMERE; TELOMERIC REPEAT BINDING PROTEIN 1; TISSUE FIXATION;

EID: 18244399643     PISSN: 02133911     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Replicative senescence and cell immortality: The role of telomeres and telomerase
2. A human telomeric protein
3. Telomerase activity is upregulated in laryngeal squamous cell carcinoma
4. Immunogold labelling of PCNA and Ki-67 antigen at the ultrastructural level in laryngeal squamous cell carcinoma and its correlation with lymph node metastasis and histological grade
5. Telomerase activity in human laryngeal squamous cell carcinomas
6. Expression of topoisomerase II alpha, Ki-67 and p53 in early stage laryngeal carcinomas not featuring vocal cord fixation
7. Specific association of human telomerase activity with immortal cells and cancer
8. Sequences-specific DNA recognition by the Myb-like domain of the human telomere binding protein TRF1: A model for the protein-DNA complex
9. Reactivation of telomerase in squamous epithelial carcinomas in the area of the head and neck
10. Telomerase activity in cancer as a diagnostic and therapeutic target
11. The relationship between survival and cell proliferation index in squamous cell carcinoma of larynx
12. The predictive value of p53, MDM-2, cyclin D1 and Ki67 in the progression from low-grade dysplasia towards carcinoma of the larynx
13. Cervical lymph node status and survival in laryngeal carcinoma: Prognostic factors
14. Telomeres, telomerase and cancer: Is the magic bullet real?
15. Telomerase in human development and cancer
16. Characterization and cell cycle regulation of the related human telomeric proteins Pin2 and TRF1 suggest a role in mitosis
17. Ki-67 (MIB1), p53 and Lewis-X (Leu M1) as prognostic factors of recurrence in T1 and T2 laryngeal carcinoma
18. Telomerase components as a diagnostic tool in human oral lesions
19. Non-radioactive semiquantitative testing for the expression levels of telomerase activity in head and neck squamous cell carcinomas may be indicative for biological tumour behaviour
20. Immunohistochemical markers of cell proliferation in laryngeal carcinoma
21. High prognostic impact of growth fraction parameters in advanced stage laryngeal squamous cell carcinoma
22. Control of telomere length by the human telomeric protein TRF1
23. Cell cycle-dependent modulation of telomerase activity in tumor cells
24. Expression of Ki67 antigen and proliferative cell nuclear antigen in benign and malignant epithelial lesions of the larynx