Involvement of adenosine A2a receptor in intraocular pressure decrease induced by 2-(1-octyn-1-yl)adenosine or 2-(6-cyano-1-hexyn-1-yl) adenosine

Journal of Pharmacological Sciences

Volumn 97, Issue 4, 2005, Pages 501-509

  Konno, Takashi ^a   Murakami, Akira ^a   Uchibori, Takehiro ^a   Nagai, Akihiko ^a   Kogi, Kentaro ^a   Nakahata, Norimichi ^b  

^a TOA EIYO LTD   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

Author keywords

2 Alkynyladenosine derivative; Adenosine A2a receptor; cAMP; Intraocular pressure; Outflow facility

Indexed keywords

2 (1 OCTYN 1 YL)ADENOSINE; 2 (6 CYANO 1 HEXYN 1 YL)ADENOSINE; 8 (3 CHLOROSTYRYL)CAFFEINE; 8 CYCLOPENTYL 1,3 DIPROPYLXANTHINE; ADENOSINE A1 RECEPTOR; ADENOSINE A2A RECEPTOR; ADENOSINE A2B RECEPTOR ANTAGONIST; ADENOSINE DERIVATIVE; ADENOSINE RECEPTOR BLOCKING AGENT; ALLOXAZINE; CYCLIC AMP; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG; 2 (1 OCTYNYL)ADENOSINE; 2-(6-CYANO-1-HEXYN-1-YL)ADENOSINE; ADENOSINE; ALKYNE; DRUG DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIHYPERTENSIVE ACTIVITY; AQUEOUS HUMOR; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG INHIBITION; DRUG MECHANISM; DRUG RECEPTOR BINDING; DRUG RESPONSE; GLAUCOMA; INTRAOCULAR HYPOTENSION; INTRAOCULAR PRESSURE; MALE; NONHUMAN; RABBIT; ANIMAL; DRUG EFFECT; HUMAN; KINETICS; METABOLISM; PHYSIOLOGY;

ADENOSINE; ALKYNES; ANIMALS; AQUEOUS HUMOR; CYCLIC AMP; GLAUCOMA; HUMANS; INTRAOCULAR PRESSURE; KINETICS; MALE; RABBITS; RECEPTOR, ADENOSINE A2A;

EID: 18244369995     PISSN: 13478613     EISSN: None     Source Type: Journal    
DOI: 10.1254/jphs.FP0040730     Document Type: Article

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