5-Lipoxygenase inhibitors: Convenient synthesis of 4-[3-(4- heterocyclylphenylthio)phenyl]-3,4,5,6-tetrahydro-2H-pyran-4-carboxamide analogues

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 10, 2005, Pages 2611-2615

  Mano, Takashi ^a   Stevens, Rodney W ^a   Okumura, Yoshiyuki ^a   Kawai, Makoto ^a   Okumura, Takako ^a   Sakakibara, Minoru ^a  

^a PFIZER INC   (United States)

Author keywords

Inhibitor; Leukotriene; Lipoxygenase; Structure activity relationship; Unsymmetric thioether

Indexed keywords

AMIDE; CALCIMYCIN; LEUKOTRIENE B4; LIPOXYGENASE INHIBITOR; PYRAN DERIVATIVE;

ARTICLE; CATALYSIS; COLUMN CHROMATOGRAPHY; CROSS COUPLING REACTION; DRUG POTENCY; DRUG SYNTHESIS; NUCLEAR OVERHAUSER EFFECT; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION;

SIGANUS;

EID: 18144425512     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.03.041     Document Type: Article

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