Synthesis and biological evaluation of new biphalin analogues with non-hydrazine linkers

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 10, 2005, Pages 2471-2475

  Mollica, Adriano ^a,b   Davis, Peg ^c   Ma, Shou Wu ^c   Lai, Josephine ^c   Porreca, Frank ^c   Hruby, Victor J ^a  

^a University of Arizona   (United States)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

Author keywords

Biphalin analogues; Linkers; Opioid agonists; Structure activity relationship

Indexed keywords

BIPHALIN; OPIATE PEPTIDE; PEPTIDE; PEPTIDE DERIVATIVE; TYROSYLALANYLGLYCYLPHENYLALANINAMIDE; UNCLASSIFIED DRUG;

AGONIST; ARTICLE; BINDING AFFINITY; DRUG ACTIVITY; DRUG POTENCY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; IN VITRO STUDY; PHARMACOPHORE; STRUCTURE ANALYSIS;

EID: 18144421193     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.03.067     Document Type: Article

References (21)

1. A.W. Lipkowski, A.M. Koneka, and I. Sroczynska Peptides 3 1982 697 700
2. A.W. Lipkowski, M. Konopka, B. Osipiak, and W.S. Gumulka K. Bláha P. Maloň Peptides 1982 1983 de Gruyter Berlin 481 486
3. P.J. Horan, A. Mattia, E.J. Bilsky, S.J. Weber, T.P. Davis, H.I. Yamamura, E. Malatynska, S.M. Appleyard, J. Slaninova, A. Misicka, A.W. Lipkowski, V.J. Hruby, and F. Porreca J. Pharmacol. Exp. Ther. 265 1993 1446 1454
4. J. Abbruscato, S.A. Thomas, V.J. Hruby, and T.P. Davis J. Neurochem. 69 1997 1236 1245
5. T.J. Abbruscato, S.A. Williams, A. Misicka, A.W. Lipkowski, V.J. Hruby, and T.P. Davis J. Pharmacol. Exp. Ther. 276 1996 1049 1057
6. M. Yamazaki, T. Suzuki, M. Nanta, and A.W. Lipkowski Life Sci. 69 2001 1023 1028
7. V.J. Hruby, T.P. Davis, R. Polt, H. Bartosz-Bechowski, A. Misicka, A. Lipkowski, S.D. Sharma, G. Li, and G. Bonner P.T.P. Kaumaya R.S. Hodges Peptides: Chemistry, Structure and Biology 1996 Mayflower Scientific Kingswinford 154 156
8. A. Misicka, A.W. Lipkowski, R. Horvath, P. Davis, F. Porreca, H.I. Yamamura, and V.J. Hruby Life Sci. 60 1997 1263 1269
9. G. Li, W. Haq, L. Xiang, B.-S. Lou, R. Hughes, I.A. De Leon, P. Davis, T.J. Gillespie, M. Romanowski, X. Zhu, A. Misicka, A.W. Lipkowski, F. Porreca, T.P. Davis, H.I. Yamamura, D.F. O'Brien, and V.J. Hruby Bioorg. Med. Chem. Lett. 8 1998 555 560
10. A.W. Lipkowski, A. Misicka, P. Davis, D. Stropova, J. Janders, M. Lachwa, F. Porreca, H.I. Yamamura, and V.J. Hruby Bioorg. Med. Chem. Lett. 9 1999 2763 2766
11. A. Misicka, A.W. Lipkowski, D. Stropova, H.I. Yamamura, P. Davis, F. Porreca, and V.J. Hruby Peptide Sci. 1999 726 727
12. A.W. Lipkowski, A.M. Konecka, I. Sroczynska, R. Przewlocki, L. Stala, and S.W. Tam Life Sci. 40 1987 2283 2388
13. So-Y. Han, and Y.-A. Kim Tetrahedron 60 2004 2447 2467
14. 2O)
15. +)
16. V. Sklenar, M. Piotto, R. Leppik, and V. Saudek J. Magn. Reson., Ser A 102 1993 241 245
17. A. Bax, and D.G. Davis J. Magn. Reson. 65 1985 355 360
18. D. Marion, M. Ikura, and A. Bax J. Magn. Reson. 84 1989 425 430
19. R. Polt, F. Porreca, L. Szabo, E.J. Bilsky, T. Davis, R. Horvath, T.J. Abbruscato, H.J. Yamamura, and V.J. Hruby Proc. Natl. Acad. Sci. U.S.A. 91 1994 7114 7118
20. A. Misicka, A.W. Lipkowski, R. Horvath, P. Davis, T.H. Kramer, H.I. Yamamura, and V.J. Hruby Life Sci. 51 1992 1025 1032
21. T.H. Kramer, P. Davis, V.J. Hruby, T.F. Burks, and F. Porreca J. Pharmacol. Exp. Ther. 266 1993 577 584