메뉴 건너뛰기




Volumn 94, Issue 2, 2005, Pages

Nonequilibrium thermodynamics and nonlinear kinetics in a cellular signaling switch

Author keywords

[No Author keywords available]

Indexed keywords

CELLULAR SIGNALING SWITCH; NONEQUILIBRIUM THERMODYNAMICS; NONLINEAR KINETICS; PHOSPHORYLATION;

EID: 18144407314     PISSN: 00319007     EISSN: 10797114     Source Type: Journal    
DOI: 10.1103/PhysRevLett.94.028101     Document Type: Article
Times cited : (108)

References (39)
  • 1
    • 2642661483 scopus 로고    scopus 로고
    • D. E. Koshland, Science 280, 852 (1998); L. H. Hartwell, J. J. Hopfield, S. Leibler, and A. W. Murray, Nature (London) 402, C47 (1999).
    • (1998) Science , vol.280 , pp. 852
    • Koshland, D.E.1
  • 4
    • 0036285634 scopus 로고    scopus 로고
    • R. Heinrich, B. G. Neel, and T. A. Rapoport, Mol. Cell 9, 957 (2002); E. Lee et al., PLoS Biol. 1, 116 (2003).
    • (2003) PLoS Biol. , vol.1 , pp. 116
    • Lee, E.1
  • 8
    • 0019996706 scopus 로고
    • A. Goldbeter and D. E. Koshland, Proc. Natl. Acad. Sci. U.S.A. 78, 6840 (1981); D. E. Koshland, A. Goldbeter, and J. B. Stock, Science 271, 220 (1982).
    • (1982) Science , vol.271 , pp. 220
    • Koshland, D.E.1    Goldbeter, A.2    Stock, J.B.3
  • 9
    • 1242274449 scopus 로고    scopus 로고
    • D. Angeli, J. E. Ferrell, and E. D. Sontag, Proc. Natl. Acad. Sci. U.S.A. 101, 1822 (2004); M. F. Testorf, A. M. Karlsson, S. P. Svensson, P. A. Oberg, and I. Lundstrom, Biophysical Chemistry 94, 1 (2001); A. Becskei and L. Serrano, Nature (London) 405, 590 (2000).
    • (2004) Proc. Natl. Acad. Sci. U.S.A. , vol.101 , pp. 1822
    • Angeli, D.1    Ferrell, J.E.2    Sontag, E.D.3
  • 11
    • 0034212551 scopus 로고    scopus 로고
    • D. Angeli, J. E. Ferrell, and E. D. Sontag, Proc. Natl. Acad. Sci. U.S.A. 101, 1822 (2004); M. F. Testorf, A. M. Karlsson, S. P. Svensson, P. A. Oberg, and I. Lundstrom, Biophysical Chemistry 94, 1 (2001); A. Becskei and L. Serrano, Nature (London) 405, 590 (2000).
    • (2000) Nature (London) , vol.405 , pp. 590
    • Becskei, A.1    Serrano, L.2
  • 12
    • 0029790351 scopus 로고    scopus 로고
    • C-Y.F. Huang and J. E. Ferrell, Proc. Natl. Acad. Sci. U.S.A. 93, 10078 (1996); J. E. Ferrell and E. M. Machleder, Science 280, 895 (1998); J. E. Ferrell and W. Xiong, Chaos 11, 227 (2001).
    • (1996) Proc. Natl. Acad. Sci. U.S.A. , vol.93 , pp. 10078
    • Huang, C.-Y.F.1    Ferrell, J.E.2
  • 13
    • 0032496358 scopus 로고    scopus 로고
    • C-Y.F. Huang and J. E. Ferrell, Proc. Natl. Acad. Sci. U.S.A. 93, 10078 (1996); J. E. Ferrell and E. M. Machleder, Science 280, 895 (1998); J. E. Ferrell and W. Xiong, Chaos 11, 227 (2001).
    • (1998) Science , vol.280 , pp. 895
    • Ferrell, J.E.1    Machleder, E.M.2
  • 14
    • 0037605637 scopus 로고    scopus 로고
    • C-Y.F. Huang and J. E. Ferrell, Proc. Natl. Acad. Sci. U.S.A. 93, 10078 (1996); J. E. Ferrell and E. M. Machleder, Science 280, 895 (1998); J. E. Ferrell and W. Xiong, Chaos 11, 227 (2001).
    • (2001) Chaos , vol.11 , pp. 227
    • Ferrell, J.E.1    Xiong, W.2
  • 17
    • 0004155427 scopus 로고
    • W. H. Freeman, San Francisco, 2nd ed.
    • L. Stryer, Biochemistry (W. H. Freeman, San Francisco, 1981), 2nd ed.
    • (1981) Biochemistry
    • Stryer, L.1
  • 19
    • 18144383410 scopus 로고    scopus 로고
    • note
    • 2 becomes implicit. The approximation, which can be made mathematically rigorous, preserves the thermodynamic consistency.
  • 20
    • 0036213422 scopus 로고    scopus 로고
    • G. P. Li and H. Qian, Traffic 3, 249 (2002); G. P. Li and H. Qian, Cell Biochem. Biophys. 39, 45 (2003).
    • (2002) Traffic , vol.3 , pp. 249
    • Li, G.P.1    Qian, H.2
  • 22
  • 23
    • 0029822793 scopus 로고    scopus 로고
    • H. R. Bourne, D. A. Sanders, and F. McCormick, Nature (London) 348, 125 (1990); V. Rybin et ed., Nature (London) 383, 266 (1996); P. Brennwald, J. Cell Biol. 149, 1 (2000).
    • (1996) Nature (London) , vol.383 , pp. 266
    • Rybin, V.1
  • 24
    • 0034599758 scopus 로고    scopus 로고
    • H. R. Bourne, D. A. Sanders, and F. McCormick, Nature (London) 348, 125 (1990); V. Rybin et ed., Nature (London) 383, 266 (1996); P. Brennwald, J. Cell Biol. 149, 1 (2000).
    • (2000) J. Cell Biol. , vol.149 , pp. 1
    • Brennwald, P.1
  • 25
    • 18144421789 scopus 로고    scopus 로고
    • note
    • Being more precise, the mechanism in (3) differs from the zero-order ultrasensitivity originally proposed by [5] which requires a saturation of kinase by A and phosphatase by A*. In (3) both enzymes are assumed in the nonsaturated linear regime (first order). The ultrasensitivity in this case is derived from the feedback, which represents the cascade behavior of the MAPK pathway. This type of ultrasensitivity could be more selective against nonspecific cross-talks. See [13] for more discussion.
  • 26
    • 18144406397 scopus 로고    scopus 로고
    • note
    • 3
  • 27
    • 0037187085 scopus 로고    scopus 로고
    • H. Qian, J. Phys. Chem. 106, 2065 (2002); H. Qian, D. A. Beard, and S. D. Liang, Eur. J. Biochem. 270, 415 (2003); D. A. Beard et al., J. Theor. Biol. 228, 327 (2004).
    • (2002) J. Phys. Chem. , vol.106 , pp. 2065
    • Qian, H.1
  • 28
    • 0037315604 scopus 로고    scopus 로고
    • H. Qian, J. Phys. Chem. 106, 2065 (2002); H. Qian, D. A. Beard, and S. D. Liang, Eur. J. Biochem. 270, 415 (2003); D. A. Beard et al., J. Theor. Biol. 228, 327 (2004).
    • (2003) Eur. J. Biochem. , vol.270 , pp. 415
    • Qian, H.1    Beard, D.A.2    Liang, S.D.3
  • 29
    • 2342627280 scopus 로고    scopus 로고
    • H. Qian, J. Phys. Chem. 106, 2065 (2002); H. Qian, D. A. Beard, and S. D. Liang, Eur. J. Biochem. 270, 415 (2003); D. A. Beard et al., J. Theor. Biol. 228, 327 (2004).
    • (2004) J. Theor. Biol. , vol.228 , pp. 327
    • Beard, D.A.1
  • 30
    • 0035926434 scopus 로고    scopus 로고
    • D. Gonze and A. Goldbeter, J. Theor. Biol. 210, 167 (2001); J. M. Vilar et al., Proc. Natl. Acad. Sci. U.S.A. 99, 5988 (2002); H. Qian, S. Saffarian, and E. L. Elson, Proc. Natl. Acad. Sci. U.S.A. 99, 10 376 (2002).
    • (2001) J. Theor. Biol. , vol.210 , pp. 167
    • Gonze, D.1    Goldbeter, A.2
  • 31
    • 0037197850 scopus 로고    scopus 로고
    • D. Gonze and A. Goldbeter, J. Theor. Biol. 210, 167 (2001); J. M. Vilar et al., Proc. Natl. Acad. Sci. U.S.A. 99, 5988 (2002); H. Qian, S. Saffarian, and E. L. Elson, Proc. Natl. Acad. Sci. U.S.A. 99, 10 376 (2002).
    • (2002) Proc. Natl. Acad. Sci. U.S.A. , vol.99 , pp. 5988
    • Vilar, J.M.1
  • 32
    • 0036679175 scopus 로고    scopus 로고
    • D. Gonze and A. Goldbeter, J. Theor. Biol. 210, 167 (2001); J. M. Vilar et al., Proc. Natl. Acad. Sci. U.S.A. 99, 5988 (2002); H. Qian, S. Saffarian, and E. L. Elson, Proc. Natl. Acad. Sci. U.S.A. 99, 10 376 (2002).
    • (2002) Proc. Natl. Acad. Sci. U.S.A. , vol.99 , pp. 10376
    • Qian, H.1    Saffarian, S.2    Elson, E.L.3
  • 35
    • 0018294282 scopus 로고
    • M. A. Savageau and R. R. Freter, Biochemistry 18, 3486 (1979); Proc. Natl. Acad. Sci. U.S.A. 76, 4507 (1979).
    • (1979) Proc. Natl. Acad. Sci. U.S.A. , vol.76 , pp. 4507
  • 37
    • 16444366591 scopus 로고
    • R. Landauer, Nature (London) 335, 779 (1988); Maxwell's Demon: Entropy, Information, Computing, edited by H. S. Leff and A. F. Rex (IoP Publishing, Bristol, 1990); P. B. Detwiler, S. Ramanathan, A. Sengupta, and B. I. Shraiman, Biophys. J. 79, 2801 (2000).
    • (1988) Nature (London) , vol.335 , pp. 779
    • Landauer, R.1
  • 38
    • 16444366591 scopus 로고
    • IoP Publishing, Bristol
    • R. Landauer, Nature (London) 335, 779 (1988); Maxwell's Demon: Entropy, Information, Computing, edited by H. S. Leff and A. F. Rex (IoP Publishing, Bristol, 1990); P. B. Detwiler, S. Ramanathan, A. Sengupta, and B. I. Shraiman, Biophys. J. 79, 2801 (2000).
    • (1990) Maxwell's Demon: Entropy, Information, Computing
    • Leff, H.S.1    Rex, A.F.2
  • 39
    • 0033637433 scopus 로고    scopus 로고
    • R. Landauer, Nature (London) 335, 779 (1988); Maxwell's Demon: Entropy, Information, Computing, edited by H. S. Leff and A. F. Rex (IoP Publishing, Bristol, 1990); P. B. Detwiler, S. Ramanathan, A. Sengupta, and B. I. Shraiman, Biophys. J. 79, 2801 (2000).
    • (2000) Biophys. J. , vol.79 , pp. 2801
    • Detwiler, P.B.1    Ramanathan, S.2    Sengupta, A.3    Shraiman, B.I.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.