Optimization of a Bifidobacterium longum production process

Journal of Biotechnology

Volumn 117, Issue 3, 2005, Pages 299-308

  Kiviharju, Kristiina ^a   Leisola, Matti ^a   Eerikäinen, Tero ^a  

^a AALTO UNIVERSITY   (Finland)

Author keywords

Bifidobacterium longum; Central composite design; Cultivation; Fractional factorial design; Freeze drying; Process optimization

Indexed keywords

BIOREACTORS; CYTOLOGY; DAIRY PRODUCTS; FOOD PROCESSING; GLUCOSE; PROTEINS; YEAST;

BIFIDOBACTERIA; CELL SUSPENSIONS; CYSTEINE; PROBIOTICS;

BACTERIA;

GLUCOSE;

ARTICLE; BACTERIUM CULTURE; BIFIDOBACTERIUM LONGUM; BIOREACTOR; CELL SUSPENSION; CONTROLLED STUDY; FREEZE DRYING; HIGH TEMPERATURE PROCEDURES; LOW TEMPERATURE PROCEDURES; NONHUMAN; PRIORITY JOURNAL; YEAST;

BIFIDOBACTERIUM LONGUM;

EID: 18144400425     PISSN: 01681656     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiotec.2005.02.007     Document Type: Article

References (17)

1. J. Ballongue Bifidobacteria and probiotic action S. Salminen A. von Wright Lactic Acid Bacteria - Microbiology and Functional Aspects 1998 Marcel Dekker New York 519 587
2. C.P. Champagne, F. Mondou, Y. Raymond, and D. Roy Effect of polymers and storage temperature on the stability of freeze-dried lactic acid bacteria Food Res. Int. 29 1996 555 562
3. M.L. Desjardins, D. Roy, C. Toupin, and J. Goulet Uncoupling of growth and acids production in Bifidobacterium spp. J. Dairy Sci. 73 1990 1478 1484
4. K.G. Fandi, H.M. Ghazali, A.M. Yazid, and A.R. Raha Purification and N-terminal amino acid sequence of fructose-6-phosphate phosphoketolase from Bifidobacterium longum BB536 Lett. Appl. Microbiol. 32 2001 235 239
5. R. Foschino, A. Galli, and E. Fiori Behavior of cultures of Bifidobacterium spp. in different conditions of freezing Ann. Microbiol. Enzymol. 45 1995 301 311
6. J. Gabrielsson, N.-O. Lindberg, and T. Lundstedt Multivariate methods in pharmaceutical applications J. Chemometrics 16 2002 141 160 (Review)
7. D.G. Gallaher, and J. Khil The effect of synbiotics on colon carcinogenesis in rats J. Nutr. 129 1999 1483S 1487S
8. R. Hartemink, B.J. Kok, G.H. Weenk, and F.M. Rombouts Raffinose-Bifidobacterium (RB) agar, a new selective medium for bifidobacteria J. Microbiol. Methods 27 1996 33 43
9. M.J. Hopkins, J.H. Cummings, and G.T. Macfarlane Inter-species differences in maximum specific growth rates and cell yields of bifidobacteria cultured on oligosaccharides and other simple carbohydrate sources J. Appl. Microbiol. 85 1998 381 386
10. K. Kiviharju, M. Leisola, and N. von Weymarn Light sensitivity of Bifidobacterium longum in bioreactor cultivations Biotechnol. Lett. 26 2004 539 542
11. J.I. Lombraña, and J.M. Díaz Heat programming to improve efficiency in a batch freeze-drier Chem. Eng. J. 35 1987 B23 B30
12. H. Maitrot, C. Paquin, C. Lacroix, and C.P. Champagne Production of concentrated freeze-dried cultures of Bifidobacterium longum in K-carrageenan-locust bean gum gel Biotechnol. Technol. 11 1997 527 531
13. T. Mattila-Sandholm, P. Myllärinen, R. Crittenden, G. Morgensen, R. Fondén, and M. Saarela Technological challenges for future probiotic foods Int. Dairy J. 12 2002 173 182
14. D.C. Montgomery Design and Analysis of Experiments 4th ed. 1997 John Wiley and Sons New York, NY
15. J. Palmfeldt, and B. Hahn-Hägerdal Influence of culture pH on survival of Lactobacillus reuteri subjected to freeze-drying Int. J. Food Microbiol. 55 2000 235 238
16. K.M.J. Van Laere, R. Hartemink, G. Beldman, S. Pitson, C. Dijkema, H.A. Schols, and A.G.J. Voragen Transglycosidase activity of Bifidobacterium adolescentis DSM 20083 α-galactosidase Appl. Microbiol. Biotechnol. 52 1999 681 688
17. 13C-glucose: a signature for Bifidobacterium fermentation in the intestinal tract J. Nutr. 128 1998 91 96