Genetic Alterations in Brain Tumors Following 1,3-Butadiene Exposure in B6C3F1 Mice

Toxicologic Pathology

Volumn 33, Issue 3, 2005, Pages 307-312

  Kim, Yongbaek ^a   Hong, Hue Hua L ^a   Lachat, Yan ^b   Clayton, Natasha P ^a   Devereux, Theodora R ^a   Melnick, Ronald L ^a   Hegi, Monika E ^b   Sills, Robert C ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

Author keywords

1,3 butadiene; B6C3F1 mouse; brain tumors; Ink4a Arf; loss of heterozygosity; mutation; neurocarcinogenesis; p53

Indexed keywords

1,3 BUTADIENE; ADENINE; GENE PRODUCT; GUANINE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN P53;

AMINO ACID SUBSTITUTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARF GENE; ARTICLE; BRAIN TUMOR; CARCINOGENESIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; FEMALE; GENE; GENE DELETION; GENE LOCUS; GENOTOXICITY; GLIOMA; HETEROZYGOSITY LOSS; INK4A GENE; MALE; MISSENSE MUTATION; MOUSE; MOUSE STRAIN; NEUROBLASTOMA; NONHUMAN; ONCOGENE H RAS; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE;

ANIMALS; BRAIN NEOPLASMS; BUTADIENES; CARCINOGENS; CODON; DNA, NEOPLASM; DOSE-RESPONSE RELATIONSHIP, DRUG; EXONS; FEMALE; GENE DELETION; GLIOMA; IMMUNOHISTOCHEMISTRY; LOSS OF HETEROZYGOSITY; MALE; MICE; MICE, INBRED STRAINS; MUTATION, MISSENSE; NEUROBLASTOMA; POLYMERASE CHAIN REACTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 18144396527     PISSN: 01926233     EISSN: None     Source Type: Journal    
DOI: 10.1080/01926230590922848     Document Type: Article

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