A novel enzymatic technique for limiting drug mobility in a hydrogel matrix

Journal of Controlled Release

Volumn 104, Issue 1, 2005, Pages 141-153

  Burke, Matthew D ^a   Park, Jung O ^b   Srinivasarao, Mohan ^b   Khan, Saad A ^c  

^a GLAXOSMITHKLINE   (United States)

^b GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^c North Carolina State University   (United States)

Author keywords

Diffusion; Enzyme; Guar; Hydrogel; Oral drug delivery

Indexed keywords

BACTERIA; CROSSLINKING; DEGRADATION; DIFFUSION; ENZYMES; HYDROGELS; LASER APPLICATIONS; OLIGOMERS; OPTICAL MICROSCOPY;

DRUG DELIVERY; DRUG MOBILITY; HYDROGEL MATRIX; MOLECULAR ARCHITECTURE;

DRUG PRODUCTS;

ALPHA GALACTOSIDASE; BACTERIAL ENZYME; BETA MANNANASE; FLUORESCEIN ISOTHIOCYANATE DEXTRAN; GALACTOMANNAN; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL MODIFICATION; CHEMICAL STRUCTURE; COLON; CONJUGATION; CROSS LINKING; DIFFUSION COEFFICIENT; DRUG DEGRADATION; DRUG DELIVERY SYSTEM; DRUG DIFFUSION; DRUG RELEASE; ENZYME ANALYSIS; ENZYME STABILITY; HYDROGEL; PHYSICAL CHEMISTRY; PRIORITY JOURNAL;

EID: 18144369994     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2005.01.017     Document Type: Article

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