Misregulation of 2μm circle copy number in a SUMO pathway mutant

Molecular and Cellular Biology

Volumn 25, Issue 10, 2005, Pages 4311-4320

  Chen, Xiaole L ^a   Reindle, Alison ^a   Johnson, Erica S ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LIGASE; RECOMBINASE; SUMO PROTEIN; DNA BINDING PROTEIN; DNA POLYMERASE; LYSINE; REP2 PROTEIN, S CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEIN; SIZ1 PROTEIN, S CEREVISIAE; SIZ2 PROTEIN, S CEREVISIAE; SUMO 1 PROTEIN; TRANSACTIVATOR PROTEIN; UBIQUITIN PROTEIN LIGASE;

ARTICLE; CELL CYCLE G2 PHASE; CONJUGATION; ENZYME ACTIVITY; ENZYME STRUCTURE; FUNGAL STRAIN; FUNGUS GROWTH; FUNGUS MUTANT; GENE DOSAGE; NONHUMAN; PHENOTYPE; PLASMID; PRIORITY JOURNAL; PROTEIN BINDING; SACCHAROMYCES CEREVISIAE; WILD TYPE; CELL CYCLE; CELL PROLIFERATION; CHEMISTRY; CYTOLOGY; GENETICS; METABOLISM; MUTATION;

CELL CYCLE; CELL PROLIFERATION; DNA NUCLEOTIDYLTRANSFERASES; DNA-BINDING PROTEINS; GENE DOSAGE; LYSINE; MUTATION; PHENOTYPE; PLASMIDS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SUMO-1 PROTEIN; TRANS-ACTIVATORS; UBIQUITIN-PROTEIN LIGASES;

EID: 18144362883     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.25.10.4311-4320.2005     Document Type: Article

References (46)

1. Ausubel, F. M., R. Brent, R. E. Kingston, D. D. Moore, J. A. Smith, J. G. Seidman, and K. Struhl. 2000. Current protocols in molecular biology. Wiley-Interscience, New York, N.Y.
2. Broach, J. R., and F. C. Volkert. 1991. Circular DNA plasmids of yeasts, p. 297-331. In J. R. Broach, E. W. Jones, and J. R. Pringle (ed.), The molecular and cellular biology of the yeast Saccharomyces, vol. 1. Cold Spring Harbor Press, Cold Spring Harbor, N.Y.
3. Chen, Y., U. Narendra, L. E. Iype, M. M. Cox, and P. A. Rice. 2000. Crystal structure of a FIp recombinase-Holliday junction complex: assembly of an active oligomer by helix swapping. Mol. Cell 6:885-897.
4. Chen, Y., and P. A. Rice. 2003. The role of the conserved Trp330 in Flp-mediated recombination. Functional and structural analysis. J. Biol. Chem. 278:24800-24807.
5. Christianson, T. W., R. S. Sikorski, M. Dante, J. H. Shero, and P. Hieter. 1992. Multifunctional yeast high-copy-number shuttle vectors. Gene 110: 119-122.
6. Denison, C., A. D. Rudner, S. A. Gerber, C. E. Bakalarski, D. Moazed, and S. P. Gygi. 2005. A proteomic strategy for gaining insights into protein sumoylation in yeast. Mol. Cell. Proteomics 4:246-254.
7. Dobson, M. J., F. E. Yull, M. Molina, S. M. Kingsman, and A. J. Kingsman. 1988. Reconstruction of the yeast 2 micron plasmid partitioning mechanism. Nucleic Acids Res. 16:7103-7117.
8. Dohmen, R. J., R. Stappen, J. P. McGrath, H. Forrova, J. Kolarov, A. Goffeau, and A. Varshavsky. 1995. An essential yeast gene encoding a homolog of ubiquitin-activating enzyme. J. Biol. Chem. 270:18099-18109.
9. Emili, A. 1998. MEC1-dependent phosphorylation of Rad9p in response to DNA damage. Mol. Cell 2:183-189.
10. Finley, D., E. Özkaynak, and A. Varshavsky. 1987. The yeast polyubiquitin gene is essential for resistance to high temperatures, starvation, and other stresses. Cell 48:1035-1046.
11. Futcher, A. B. 1986. Copy number amplification of the 2 micron circle plasmid of Saccharomyces cerevisiae. 3. Theor. Biol. 119:197-204.
12. Gill, G. 2004. SUMO and ubiquitin in the nucleus: different functions, similar mechanisms? Genes Dev. 18:2046-2059.
13. Hannich, J. T., A. Lewis, M. B. Kroetz, S. J. Li, H. Heide, A. Emili, and M. Hochstrasser. 2005. Defining the SUMO-modified proteome by multiple approaches in Saccharomyces cerevisiae. J. Biol. Chem. 280:4102-4110.
14. Haracska, L., C. A. Torres-Ramos, R. E. Johnson, S. Prakash, and L. Prakash. 2004. Opposing effects of ubiquitin conjugation and SUMO modification of PCNA on replicational bypass of DNA lesions in Saccharomyces cerevisiae. Mol. Cell. Biol. 24:4267-4274.
15. Hershko, A., and A. Ciechanover. 1998. The ubiquitin system. Annu. Rev. Biochem. 67:425-479.
16. Hoege, C., B. Pfander, G. L. Moldovan, G. Pyrowolakis, and S. Jentsch. 2002. RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO. Nature 419:135-141.
17. Hoffman, C. S., and F. Winston. 1987. A ten-minute DNA preparation from yeast efficiently releases autonomous plasmids for transformation of Escherichia coli. Gene 57:267-272.
18. Holm, C. 1982. Clonal lethality caused by the yeast plasmid 2 mu DNA. Cell 29:585-594.
19. Holm, C. 1982. Sensitivity to the yeast plasmid 2mu DNA is conferred by the nuclear allele nib1. Mol. Cell. Biol. 2:985-992.
20. Johnson, E. S. 2004. Protein modification by SUMO. Annu. Rev. Biochem. 73:355-382.
21. Johnson, E. S., and G. Blobel. 1999. Cell cycle-regulated attachment of the ubiquitin-related protein SUMO to the yeast septins. J. Cell Biol. 147: 981-994.
22. Johnson, E. S., and A. A. Gupta. 2001. An E3-like factor that promotes SUMO conjugation to the yeast septins. Cell 106:735-744.
23. Johnson, E. S., I. Schwienhorst, R. J. Dohmen, and G. Blobel. 1997. The ubiquitin-like protein Smt3p is activated for conjugation to other proteins by an Aos1p/Uba2p heterodimer. EMBO J. 16:5509-5519.
24. Li, S. J., and M. Hochstrasser. 1999. A new protease required for cell-cycle progression in yeast. Nature 398:246-251.
25. -ΔΔCT method. Methods 25: 402-408.
26. Mead, D. J., D. C. Gardner, and S. G. Oliver. 1986. The yeast 2 micron plasmid: strategies for the survival of a selfish DNA. Mol. Gen. Genet. 205: 417-421.
27. Mehta, S., X. M. Yang, C. S. Chan, M. J. Dobson, M. Jayaram, and S. Velmurugan. 2002. The 2 micron plasmid purloins the yeast cohesin complex: a mechanism for coupling plasmid partitioning and chromosome segregation? J. Cell Biol. 158:625-637.
28. Müller, S., A. Ledl, and D. Schmidt. 2004. SUMO: a regulator of gene expression and genome integrity. Oncogene 23:1998-2008.
29. Murray, J. A., M. Scarpa, N. Rossi, and G. Cesareni. 1987. Antagonistic controls regulate copy number of the yeast 2 mu plasmid. EMBO J. 6: 4205-4212.
30. Panse, V. G., U. Hardeland, T. Werner, B. Kuster, and E. Hurt. 2004. A proteome-wide approach identifies sumolyated substrate proteins in yeast. J. Biol. Chem. 279:41346-41351.
31. Pickart, C. M. 2001. Mechanisms underlying ubiquitination. Annu. Rev. Biochem. 70:503-533.
32. Reynolds, A. E., A. W. Murray, and J. W. Szostak. 1987. Roles of the 2çéì gene products in stable maintenance of the 2mμ plasmid of Saccharomyces cerevisiae. Mol. Cell. Biol. 7:3566-3573.
33. Schwienhorst, I., E. S. Johnson, and R. J. Dohmen. 2000. SUMO conjugation and deconjugation. Mol. Gen. Genet. 263:771-786.
34. Sengupta, A., K. Blomqvist, A. J. Pickett, Y. Zhang, J. S. Chew, and M. J. Dobson. 2001. Functional domains of yeast plasmid-encoded Rep proteins. J. Bacteriol. 183:2306-2315.
35. Seufert, W., B. Futcher, and S. Jentsch. 1995. Role of a ubiquitin-conjugating enzyme in degradation of S- and M-phase cyclins. Nature 373:78-81.
36. Sherman, F., G. R. Fink, and J. B. Hicks. 1986. Methods in yeast genetics. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
37. Stelter, P., and H. D. Ulrich. 2003. Control of spontaneous and damage-induced mutagenesis by SUMO and ubiquitin conjugation. Nature 425:188-191.
38. Strunnikov, A. V., L. Aravind, and E. V. Koonin. 2001. Saccharomyces cerevisiae SMT4 encodes an evolutionary conserved protease with a role in chromosome condensation regulation. Genetics 158:95-107.
39. Takahashi, Y., A. Toh-e, and Y. Kikuchi. 2001. A novel factor required for the SUMO1/Smt3 conjugation of yeast septins. Gene 275:223-231.
40. Vialard, J. E., C. S. Gilbert, C. M. Green, and N. F. Lowndes. 1998. The budding yeast Rad9 checkpoint protein is subjected to Mec1/Tel1-dependent hyperphosphorylation and interacts with Rad53 after DNA damage. EMBO J. 17:5679-5688.
41. Wohlschlegel, J. A., E. S. Johnson, S. I. Reed, and J. R. Yates III. 2004. Global analysis of protein sumoylation in Saccharomyces cerevisiae. J. Biol. Chem. 279:45662-45668.
42. Wong, M. C., S. R. Scott-Drew, M. J. Hayes, P. J. Howard, and J. A. Murray. 2002. RSC2, encoding a component of the RSC nucleosome remodeling complex, is essential for 2mμ plasmid maintenance in Saccharomyces cerevisiae. Mol. Cell. Biol. 22:4218-4229.
43. Yaffe, M. P., and G. Schatz. 1984. Two nuclear mutations that block mitochondrial protein import in yeast. Proc. Natl. Acad. Sci. USA 81:4819-4823.
44. Yang, X. M., S. Mehta, D. Uzri, M. Jayaram, and S. Velmurugan. 2004. Mutations in a partitioning protein and altered chromatin structure at the partitioning locus prevent cohesin recruitment by the Saccharomyces cerevisiae plasmid and cause plasmid missegregation. Mol. Cell. Biol. 24:5290-5303.
45. Zhao, X., C. Y. Wu, and G. Blobel. 2004. Mlp-dependent anchorage and stabilization of a desumoylating enzyme is required to prevent clonal lethality. J. Cell Biol. 167:605-611.
46. Zhou, W., J. J. Ryan, and H. Zhou. 2004. Global analyses of sumoylated proteins in Saccharomyces cerevisiae. Induction of protein sumoylation by cellular stresses. J. Biol. Chem. 279:32262-32268.