Myocardial oxygenation and adenosine release in isolated guinea pig hearts during changes in contractility

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 288, Issue 5 57-5, 2005, Pages

  Ejike, J Chiaka ^a,e   Arakaki, Lorilee S L ^a   Beard, Daniel A ^b,f   Ciesielski, Wayne A ^d   Feigl, Eric O ^c   Schenkman, Kenneth A ^a,b,c,d  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b University of Washington   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

^d SEATTLE CHILDREN S RESEARCH INSTITUTE   (United States)

^e LOMA LINDA UNIVERSITY   (United States)

^f MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

Buffer perfused heart; Hypoxia; Myoglobin

Indexed keywords

ADENOSINE; ADRENALIN; BUFFER; MYOGLOBIN; POTASSIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COMPUTER MODEL; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; CORONARY VEIN; GUINEA PIG; HEART ARREST; HEART LEFT VENTRICLE PRESSURE; HEART MUSCLE CONTRACTILITY; HEART MUSCLE OXYGEN CONSUMPTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; NEAR INFRARED SPECTROSCOPY; NONHUMAN; PRIORITY JOURNAL; VENOUS OXYGEN TENSION;

ADENOSINE; ANIMALS; ANOXIA; BUFFERS; EPINEPHRINE; GUINEA PIGS; MALE; MYOCARDIAL CONTRACTION; MYOCARDIUM; OXYGEN; OXYGEN CONSUMPTION; POTASSIUM CHLORIDE; SYMPATHOMIMETICS;

EID: 18044381170     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.00777.2004     Document Type: Article

References (31)

1. Altman PL and Dittmer DS. Respiration and Circulation Handbook. Bethesda, MD: FASEB, 1971, p. 18.
2. Bache RJ, Dai XZ, Schwartz JS, and Homans DC. Role of adenosine in coronary vasodilation during exercise. Circ Res 62: 846-853, 1988.
3. Bache RJ, Zhang J, Murakami Y, Zhang Y, Cho YK, Merkle H, Gong G, From AH, and Ugurbil K. Myocardial oxygenation at high workstates in hearts with left ventricular hypertrophy. Cardiovasc Res 42: 616-626, 1999.
4. Bardenheuer H and Schrader J. Relationship between myocardial oxygen consumption, coronary flow, and adenosine release in an improved isolated working heart preparation of guinea pigs. Circ Res 52: 263-271, 1983.
5. Bardenheuer H and Schrader J. Supply-to-demand ratio for oxygen determines formation of adenosine by the heart. Am J Physiol Heart Circ Physiol 250: H173-H180, 1986.
6. Beard DA, Schenkman KA, and Feigl EO. Myocardial oxygenation in isolated hearts predicted by an anatomically realistic microvascular transport model. Am J Physiol Heart Circ Physiol 285: H1826-H1836, 2003.
7. Bunger R, Haddy FJ, and Gerlach E. Coronary responses to dilating substances and competitive inhibition by theophylline in the isolated perfused guinea pig heart. Pflügers Arch 358: 213-224, 1975.
8. Chung Y and Jue T. Regulation of respiration in myocardium in the transient and steady state. Am J Physiol Heart Circ Physiol 277: H1410-H1417, 1999.
9. DeWitt DF, Wangler RD, Thompson CI, and Sparks HV Jr. Phasic release of adenosine during steady state metabolic stimulation in the isolated guinea pig heart. Circ Res 53: 636-643, 1983.
10. Duncker DJ, Stubenitsky R, and Verdouw PD. Autonomic control of vasomotion in the porcine coronary circulation during treadmill exercise: evidence for feed-forward beta-adrenergic control. Circ Res 82: 1312-1322, 1998.
11. Feigl EO. Coronary physiology. Physiol Rev 63: 1-205, 1983.
12. Goldman D and Popel AS. A computational study of the effect of capillary network anastomoses and tortuosity on oxygen transport. J Theor Biol 206: 181-194, 2000.
13. Gorman MW, Tune JD, Richmond KN, and Feigl EO, Feedforward sympathetic coronary vasodilation in exercising dogs. J Appl Physiol 89: 1892-1902, 2000.
14. He MX, Gorman MW, Romig GD, Meyer RA, and Sparks HV Jr. Adenosine formation and energy status during hypoperfusion and 2-deoxyglucose infusion. Am J Physiol Heart Circ Physiol 260: H917-H926, 1991.
15. He MX, Wangler RD, Dillon PF, Romig GD, and Sparks HV. Phosphorylation potential and adenosine release during norepinephrine infusion in guinea pig heart. Am J Physiol Heart Circ Physiol 253: H1184-H1191, 1987.
16. Headrick J, Clarke K, and Willis RJ. Adenosine production and energy metabolism in ischaemic and metabolically stimulated rat heart. J Mol Cell Cardiol 21: 1089-1100, 1989.
17. Headrick JP, Matherne GP, Berr SS, Han DC, and Berne RM. Metabolic correlates of adenosine formation in stimulated guinea pig heart. Am J Physiol Heart Circ Physiol 260: H165-H172, 1991.
18. Heineman FW, Kupriyanov VV, Marshall R, Fralix TA, and Balaban RS. Myocardial oxygenation in the isolated working rabbit heart as a function of work. Am J Physiol Heart Circ Physiol 262: H255-H267, 1992.
19. Kreutzer U, Mekhamer Y, Chung Y, and Jue T. Oxygen supply and oxidative phosphorylation limitation in rat myocardium in situ. Am J Physiol Heart Circ Physiol 280: H2030-H2037, 2001.
20. Kreutzer U, Mekhamer Y, Tran TK, and Jue T. Role of oxygen in limiting respiration in the in situ myocardium. J Mol Cell Cardiol 30: 2651-2655, 1998.
21. Murakami Y, Zhang Y, Cho YK, Mansoor AM, Chung JK, Chu C, Francis G, Ugurbil K, Bache RJ, From AH, Jerosch-Herold M, Wilke N, and Zhang J. Myocardial oxygenation during high work states in hearts with postinfarction remodeling. Circulation 99: 942-948, 1999.
22. Nayler WG, Price JM, and Lowe TE. Inhibition of adenosine-induced coronary vasodilatation. Cardiovasc Res 1: 63-66, 1967.
23. Schenkman KA. Cardiac performance as a function of intracellular oxygen tension in buffer-perfused hearts. Am J Physiol Heart Circ Physiol 281: H2463-H2472, 2001.
24. Schenkman KA, Beard DA, Ciesielski WA, and Feigl EO. Comparison of buffer and red cell perfusion of guinea pig heart oxygenation. Am J Physiol Heart Circ Physiol 285: H1819-H1825, 2003.
25. Schenkman KA and Ciesielski WA. Improved myoglobin saturation measurement made by partial least-squares analysis of optical reflectance spectra. Appl Spectrosc 56: 1215-1221, 2002.
26. Schenkman KA, Marble DR, Burns DH, and Feigl EO. Optical spectroscopic method for in vivo measurement of cardiac myoglobin oxygen saturation. Appl Spectrosc 53: 332-338, 1999.
27. Schenkman KA, Marble DR, Feigl EO, and Burns DH. Near-infrared spectroscopic measurement of myoglobin oxygen saturation in the presence of hemoglobin using partial least-squares analysis. Appl Spectrosc 53: 325-331, 1999.
28. 2 in stimulated rat cardiomyocytes. Am J Physiol Heart Circ Physiol 273: H756-H766, 1997.
29. Tune JD, Gorman MW, and Feigl EO. Matching coronary blood flow to myocardial oxygen consumption. J Appl Physiol 97: 404-415, 2004.
30. Tune JD, Richmond KN, Gorman MW, Olsson RA, and Feigl EO. Adenosine is not responsible for local metabolic control of coronary blood flow in dogs during exercise. Am J Physiol Heart Circ Physiol 278: H74-H84, 2000.
31. Zhang J, Murakami Y, Zhang Y, Cho YK, Ye Y, Gong G, Bache RJ, Ugurbil K, and From AH. Oxygen delivery does not limit cardiac performance during high work states. Am J Physiol Heart Circ Physiol 277: H50-H57, 1999.