Systemic adjuvant effect of cholera toxin in the chicken

Veterinary Immunology and Immunopathology

Volumn 70, Issue 1-2, 1999, Pages 135-141

  Quéré, Pascale ^a   Girard, Fabienne ^a  

^a CEMAGREF   (France)

Author keywords

Antibody production; Chicken; Cholera toxin; Intravenous adjuvant activity; Lymphocyte proliferation

Indexed keywords

ADJUVANT; CHOLERA TOXIN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN A ANTIBODY; KEYHOLE LIMPET HEMOCYANIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY PRODUCTION; ANTIBODY RESPONSE; ARTICLE; CHICKEN; CONTROLLED STUDY; IMMUNE RESPONSE; IMMUNIZATION; IMMUNOMODULATION; INTRAVENOUS DRUG ADMINISTRATION; LYMPHOCYTE PROLIFERATION; NONHUMAN;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; CELLS, CULTURED; CHICKENS; CHOLERA TOXIN; ENZYME-LINKED IMMUNOSORBENT ASSAY; HEMOCYANIN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN CLASS SWITCHING; LYMPHOCYTE ACTIVATION;

GALLUS GALLUS; MAMMALIA;

EID: 17944402904     PISSN: 01652427     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-2427(99)00060-4     Document Type: Article

References (16)

1. Bromander A.K., Holmgren J., Lycke N. Cholera toxin stimulates IL-1 production and enhances antigen presentation by macrophages in vitro. J. Immunol. 146:1991;2908-2914.
2. Bromander A.K., Kjerrulf M., Holmgren J., Lycke N. Cholera toxin enhances alloantigen presentation by cultured intestinal epithelial cells. Scand. J. Immunol. 37:1993;452-458.
3. Cong Y., Weaver C.T., Elson C.O. The mucosal adjuvanticity of cholera toxin involves enhancement of costimulatory activity by selective up-regulation of B7.2 expression. J. Immunol. 159:1997;5301-5308.
4. Elson C.O., Holland S.P., Dertzbaugh M.T., Cuff C.F., Anderson A.O. Morphologic and functional alterations of mucosal T cells by cholera toxin and its B subunit. J. Immunol. 154:1995;1032-1040.
5. Hornquist C.E., Lycke N. Cholera toxin adjuvant greatly promotes antigen priming of T cells. Eur. J. Immunol. 23:1993;2136-2143.
6. Hornquist C.E., Grdic D., Mak T., Lycke N. CD8-deficient mice exhibit augmented mucosal immune responses and intact adjuvant effects to cholera toxin. Immunology. 87:1996;220-229.
7. Hornquist C.E., Ekman L., Grdic K.D., Schon K., Lycke N.Y. Paradoxical IgA immunity in CD4-deficient mice. Lack of cholera toxin-specific protective immunity despite normal gut mucosal IgA differentiation. J. Immunol. 155:1995;2877-2887.
8. Hoshi S., Nakamura T., Nunoya T., Ueda S. Induction of protective immunity in chickens orally immunized with inactivated infectious bursal disease virus. Vaccine. 13:1995;245-252.
9. Hyun C.S., Kimmich G.A. Interaction of cholera toxin and Escherichia coli enterotoxin with isolated intestinal epithelial cells. Am. J. Physiol. 247:1984;G623-G631.
10. Lycke N.Y. Cholera toxin promotes B cell isotype switching by two different mechanisms. cAMP induction augments germ-line Ig H-chain RNA transcripts whereas membrane ganglioside GM1-receptor binding enhances later events in differentiation. J. Immunol. 150:1993;4810-4821.
11. Meinersmann R.J., Porter R.E. Effect of Vibrio cholerae toxin on oral immunization of chickens. Avian Dis. 37:1993;427-432.
12. Papadimitriou E., Mintzas A., Skoutari M., Dimitracopoulos G., Anastassiou E.D. Cholera toxin stimulates human B-cell DR antigen biosynthesis at the level of translation. Cell. Immunol. 180:1997;176-184.
13. Snider D.P. The mucosal adjuvant activities of ADP-ribosylating bacterial enterotoxins. Crit. Rev. Immunol. 15:1995;317-348.
14. Vajdy M., Kosko-Vilbois M.H., Kopf M., Kohler G., Lycke N. Impaired mucosal immune responses in interleukin 4-targeted mice. J. Exp. Med. 181:1995;41-53.
15. Vervelde L., Janse E.M., Vermeulen A.N., Jeurissen S.H. Induction of a local and systemic immune response using cholera toxin as vehicle to deliver antigen in the lamina propria of the chicken intestine. Vet. Immunol. Immunopathol. 62:1998;261-272.
16. Xu-Amano J., Jackson R.J., Fujihashi K., Kiyono H., Staats H.F., McGhee J.R. Helper Th1 and Th2 cell responses following mucosal or systemic immunization with cholera toxin. Vaccine. 12:1994;903-911.